Ectopic Fat and Insulin Resistance: Pathophysiology and Effect of Diet and Lifestyle Interventions Tập 2012 - Trang 1-18 - 2012
Marieke Snel, Jacqueline T. Jonker, Jan W. Schoones, Hildo J. Lamb, Albert de Roos, Hanno Pijl, Johannes W. A. Smit, A E Meinders, Ingrid M. Jazet
The storage of triglyceride (TG) droplets in nonadipose tissues is called
ectopic fat storage. Ectopic fat is associated with insulin resistance and type
2 diabetes mellitus (T2DM). Not the triglycerides per se but the accumulation of
intermediates of lipid metabolism in organs, such as the liver, skeletal muscle,
and heart seem to disrupt metabolic processes and impair organ function. We
describe... hiện toàn bộ
Comparison of QCT and DXA: Osteoporosis Detection Rates in Postmenopausal Women Tập 2013 - Trang 1-5 - 2013
Na Li, Xinmin Li, Xu Li, Wei Sun, Xiaoguang Cheng, Wei Tian
Objective. To compare the osteoporosis detection rates in postmenopausal women
when measuring bone mineral density (BMD) with quantitative computed tomography
(QCT) in the spine versus dual X-ray absorptiometry (DXA) in the spine and hip
and to investigate the reasons for the discrepancy between the two
techniques.Methods. Spinal volumetric BMD was measured with QCT, and areal
spinal and hip BMDs ... hiện toàn bộ
Update on Anaplastic Thyroid Carcinoma: Morphological, Molecular, and Genetic Features of the Most Aggressive Thyroid Cancer Tập 2014 - Trang 1-13 - 2014
Moira Ragazzi, Alessia Ciarrocchi, Valentina Sancisi, Greta Gandolfi, Alessandra Bisagni, Simonetta Piana
Anaplastic thyroid carcinoma (ATC) is the most aggressive form of thyroid
cancer. It shows a wide spectrum of morphological presentations and the
diagnosis could be challenging due to its high degree of dedifferentiation.
Molecular and genetic features of ATC are widely heterogeneous as well and many
efforts have been made to find a common profile in order to clarify its
cancerogenetic process. A ... hiện toàn bộ
Systematic Review of Primary Hyperparathyroidism in India: The Past, Present, and the Future Trends Tập 2011 - Trang 1-7 - 2011
P. V. Pradeep, B. Jayashree, Anjali Mishra, Saroj Kanta Mishra
Primary hyperparathyroidism (PHPT) has become an asymptomatic disease in the
Western world with the introduction of routine calcium screening. However, the
same phenomenon is not observed in India. We have now systematically reviewed
the status of PHPT in India. While there is a paucity of literature on PHPT from
India when compared to Western countries, some information can be gleaned upon.
Most ... hiện toàn bộ
Metabolic and Clinical Consequences of Hyperthyroidism on Bone Density Tập 2013 - Trang 1-11 - 2013
Jagoda Gorka, Regina M. Taylor‐Gjevre, Terra Arnason
In 1891, Von Recklinghausen first established the association between the
development of osteoporosis in the presence of overt hyperthyroidism. Subsequent
reports have demonstrated that BMD loss is common in frank hyperthyroidism, and,
to a lesser extent, in subclinical presentations. With the introduction of
antithyroid medication in the 1940s to control biochemical hyperthyroidism, the
accompany... hiện toàn bộ
Surgery and Radiosurgery for Acromegaly: A Review of Indications, Operative Techniques, Outcomes, and Complications Tập 2012 - Trang 1-7 - 2012
Yvette Marquez, Alexander Tuchman, Gabriel Zada
Among multimodality treatments for acromegaly, the goals of surgical
intervention are to balance maximal tumor resection while preserving normal
pituitary function and maintaining patient safety. The resection of growth
hormone-(GH-) secreting pituitary adenomas in the hands of experienced surgeons
results in hormonal remission in 50–70% of patients. Acromegalic patients often
have medical comorbi... hiện toàn bộ
Challenges of Diabetes Self-Management in Adults Affected by Food Insecurity in a Large Urban Centre of Ontario, Canada Tập 2015 - Trang 1-9 - 2015
Justine Chan, Margaret DeMelo, Jacqui Gingras, Enza Gucciardi
Objective.To explore how food insecurity affects individuals’ ability to manage
their diabetes, as narrated by participants living in a large, culturally
diverse urban centre.Design.Qualitative study comprising of in-depth interviews,
using a semistructured interview guide.Setting.Participants were recruited from
the local community, three community health centres, and a community-based
diabetes e... hiện toàn bộ
Stereotactic Irradiation of GH-Secreting Pituitary Adenomas Tập 2012 - Trang 1-7 - 2012
Giuseppe Minniti, Claudia Scaringi, Dante Amelio, R. Maurizi Enrici
Radiotherapy (RT) is often employed in patients with acromegaly refractory to
medical and/or surgical interventions in order to prevent tumour regrowth and
normalize elevated GH and IGF-I levels. It achieves tumour control and hormone
normalization up to 90% and 70% of patients at 10–15 years. Despite the
excellent tumour control, conventional RT is associated with a potential risk of
developing l... hiện toàn bộ
GnRH Agonist versus hCG Trigger in Ovulation Induction with Intrauterine Insemination: A Randomized Controlled Trial Tập 2019 - Trang 1-6 - 2019
Minh Tâm Lê, Đắc Nguyên Nguyễn, Jessica R. Zolton, Vũ Quốc Huy Nguyễn, Quang Vinh Truong, Ngọc Thành Cao, Alan H. DeCherney, Micah J. Hill
This study is aimed at comparing clinical pregnancy rates (CPRs) in patients who
are administered either gonadotropin-releasing hormone agonist (GnRHa) or human
chorionic gonadotropin (hCG) for ovulation trigger in intrauterine insemination
(IUI) cycles. A prospective randomized comparative study was conducted at Hue
University Hospital in Vietnam. A total of 197 infertile women were randomly
assi... hiện toàn bộ