International Journal of Endocrinology
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Ectopic Fat and Insulin Resistance: Pathophysiology and Effect of Diet and Lifestyle Interventions
International Journal of Endocrinology - Tập 2012 - Trang 1-18 - 2012
The storage of triglyceride (TG) droplets in nonadipose tissues is called
ectopic fat storage. Ectopic fat is associated with insulin resistance and type
2 diabetes mellitus (T2DM). Not the triglycerides per se but the accumulation of
intermediates of lipid metabolism in organs, such as the liver, skeletal muscle,
and heart seem to disrupt metabolic processes and impair organ function. We
describe...
Systematic Review of Primary Hyperparathyroidism in India: The Past, Present, and the Future Trends
International Journal of Endocrinology - Tập 2011 - Trang 1-7 - 2011
Primary hyperparathyroidism (PHPT) has become an asymptomatic disease in the
Western world with the introduction of routine calcium screening. However, the
same phenomenon is not observed in India. We have now systematically reviewed
the status of PHPT in India. While there is a paucity of literature on PHPT from
India when compared to Western countries, some information can be gleaned upon.
Most ...
Update on Anaplastic Thyroid Carcinoma: Morphological, Molecular, and Genetic Features of the Most Aggressive Thyroid Cancer
International Journal of Endocrinology - Tập 2014 - Trang 1-13 - 2014
Anaplastic thyroid carcinoma (ATC) is the most aggressive form of thyroid
cancer. It shows a wide spectrum of morphological presentations and the
diagnosis could be challenging due to its high degree of dedifferentiation.
Molecular and genetic features of ATC are widely heterogeneous as well and many
efforts have been made to find a common profile in order to clarify its
cancerogenetic process. A ...
GnRH Agonist versus hCG Trigger in Ovulation Induction with Intrauterine Insemination: A Randomized Controlled Trial
International Journal of Endocrinology - Tập 2019 - 2019
This study is aimed at comparing clinical pregnancy rates (CPRs) in patients who
are administered either gonadotropin-releasing hormone agonist (GnRHa) or human
chorionic gonadotropin (hCG) for ovulation trigger in intrauterine insemination
(IUI) cycles. A prospective randomized comparative study was conducted at Hue
University Hospital in Vietnam. A total of 197 infertile women were randomly
assi...
Gamma Knife Radiosurgery for Acromegaly
International Journal of Endocrinology - Tập 2012 - Trang 1-7 - 2012
Acromegaly is debilitating disease occasionally refractory to surgical and
medical treatment. Stereotactic radiosurgery, and in particular Gamma Knife
surgery (GKS), has proven to be an effective noninvasive adjunct to traditional
treatments, leading to disease remission in a substantial proportion of
patients. Such remission holds the promise of eliminating the need for expensive
medications, alo...
Stereotactic Irradiation of GH-Secreting Pituitary Adenomas
International Journal of Endocrinology - Tập 2012 - Trang 1-7 - 2012
Radiotherapy (RT) is often employed in patients with acromegaly refractory to
medical and/or surgical interventions in order to prevent tumour regrowth and
normalize elevated GH and IGF-I levels. It achieves tumour control and hormone
normalization up to 90% and 70% of patients at 10–15 years. Despite the
excellent tumour control, conventional RT is associated with a potential risk of
developing l...
Surgery and Radiosurgery for Acromegaly: A Review of Indications, Operative Techniques, Outcomes, and Complications
International Journal of Endocrinology - Tập 2012 - Trang 1-7 - 2012
Among multimodality treatments for acromegaly, the goals of surgical
intervention are to balance maximal tumor resection while preserving normal
pituitary function and maintaining patient safety. The resection of growth
hormone-(GH-) secreting pituitary adenomas in the hands of experienced surgeons
results in hormonal remission in 50–70% of patients. Acromegalic patients often
have medical comorbi...
Challenges of Diabetes Self-Management in Adults Affected by Food Insecurity in a Large Urban Centre of Ontario, Canada
International Journal of Endocrinology - Tập 2015 - Trang 1-9 - 2015
Objective.To explore how food insecurity affects individuals’ ability to manage
their diabetes, as narrated by participants living in a large, culturally
diverse urban centre.Design.Qualitative study comprising of in-depth interviews,
using a semistructured interview guide.Setting.Participants were recruited from
the local community, three community health centres, and a community-based
diabetes e...
GnRH Agonist versus hCG Trigger in Ovulation Induction with Intrauterine Insemination: A Randomized Controlled Trial
International Journal of Endocrinology - Tập 2019 - Trang 1-6 - 2019
This study is aimed at comparing clinical pregnancy rates (CPRs) in patients who
are administered either gonadotropin-releasing hormone agonist (GnRHa) or human
chorionic gonadotropin (hCG) for ovulation trigger in intrauterine insemination
(IUI) cycles. A prospective randomized comparative study was conducted at Hue
University Hospital in Vietnam. A total of 197 infertile women were randomly
assi...
Comparison of QCT and DXA: Osteoporosis Detection Rates in Postmenopausal Women
International Journal of Endocrinology - Tập 2013 - Trang 1-5 - 2013
Objective. To compare the osteoporosis detection rates in postmenopausal women
when measuring bone mineral density (BMD) with quantitative computed tomography
(QCT) in the spine versus dual X-ray absorptiometry (DXA) in the spine and hip
and to investigate the reasons for the discrepancy between the two
techniques.Methods. Spinal volumetric BMD was measured with QCT, and areal
spinal and hip BMDs ...
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