TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunityImmunological Reviews - Tập 235 Số 1 - Trang 172-189 - 2010
Gordon J. Freeman, José M. Casasnovas, Dale T. Umetsu, Rosemarie H. DeKruyff
Summary: The TIM (T cell/transmembrane, immunoglobulin, and mucin) gene family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity, and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific recognition of ph...... hiện toàn bộ
Inflammasomes: guardians of cytosolic sanctityImmunological Reviews - Tập 227 Số 1 - Trang 95-105 - 2009
Mohamed Lamkanfi, Vishva M. Dixit
Summary: The innate immune system is critical in recognizing bacterial and viral infections to evoke a proper immune response. Certain members of the intracellular nucleotide‐binding and oligomerization domain (NOD)‐like receptor (NLR) family detect microbial components in the cytosol and trigger the assembly of large caspase‐1‐activating complexes termed inflammaso...... hiện toàn bộ
The role of B cells and alloantibody in the host response to human organ allograftsImmunological Reviews - Tập 196 Số 1 - Trang 197-218 - 2003
Attapong Vongwiwatana, Adis Tasanarong, Luis Hidalgo, Philip F. Halloran
Summary: Some human organ transplants deteriorate slowly over a period of years, often developing characteristic syndromes: transplant glomerulopathy (TG) in kidneys, bronchiolitis obliterans in lungs, and coronary artery disease in hearts. In the past, we attributed late graft deterioration to ‘chronic rejection’, a distinct but mysterious immunologic process diffe...... hiện toàn bộ
A bacteriophages journey through the human bodyImmunological Reviews - Tập 279 Số 1 - Trang 106-122 - 2017
Jeremy J. Barr
SummaryThe human body is colonized by a diverse collective of microorganisms, including bacteria, fungi, protozoa and viruses. The smallest entity of this microbial conglomerate are the bacterial viruses. Bacteriophages, or phages for short, exert significant selective pressure on their bacterial hosts, undoubtedly influencing the human microbiome and its impact on...... hiện toàn bộ