IUBMB Life
SCIE-ISI SCOPUS (1999-2023)
1521-6543
1521-6551
Mỹ
Cơ quản chủ quản: WILEY , Wiley-Blackwell
Lĩnh vực:
Molecular BiologyClinical BiochemistryGeneticsBiochemistryCell Biology
Các bài báo tiêu biểu
The extraordinary ligand binding properties of human serum albumin
Tập 57 Số 12 - Trang 787-796 - 2005
Mammalian polyamine metabolism and functionAbstract Polyamines are ubiquitous small basic molecules that play multiple essential roles in mammalian physiology. Their cellular content is highly regulated and there is convincing evidence that altered metabolism is involvement in many disease states. Drugs altering polyamine levels may therefore have a variety of important targets. This review will summarize th... ... hiện toàn bộ
Tập 61 Số 9 - Trang 880-894 - 2009
Đường đi Kennedy—Tổng hợp De novo của phosphatidylethanolamine và phosphatidylcholine Dịch bởi AI Tóm tắt Các glycerophospholipid phosphatidylcholine (PC) và phosphatidylethanolamine (PE) chiếm hơn 50% tổng số loài phospholipid trong màng eukaryote và do đó đóng vai trò quan trọng trong cấu trúc và chức năng của các màng này. Trong hầu hết các tế bào eukaryote, PC và PE được tổng hợp thông qua phản ứng aminocoholphosphotransferase, sử dụng sn... hiện toàn bộ
Tập 62 Số 6 - Trang 414-428 - 2010
The monocarboxylate transporter family—Role and regulationAbstract Monocarboxylate transporter (MCT) isoforms 1–4 catalyze the proton‐linked transport of monocarboxylates such as L ‐lactate across the plasma membrane, whereas MCT8 and MCT10 are thyroid hormone and aromatic amino acid transporters, respectively. The importance of MCTs is becoming increasingly evident as their extensive physiological and pa... ... hiện toàn bộ
Tập 64 Số 2 - Trang 109-119 - 2012
DDT, pyrethrins, pyrethroids and insect sodium channelsAbstract The long term use of many insecticides is continually threatened by the ability of insects to evolve resistance mechanisms that render the chemicals ineffective. Such resistance poses a serious threat to insect pest control both in the UK and worldwide. Resistance may result from either an increase in the ability of the insect to detoxify the insecticide or... ... hiện toàn bộ
Tập 59 Số 3 - Trang 151-162 - 2007
Glucose‐6‐phosphate dehydrogenase, NADPH, and cell survivalAbstract Glucose‐6‐phosphate dehydrogenase (G6PD) is the rate‐limiting enzyme of the pentose phosphate pathway. Many scientists think that the roles and regulation of G6PD in physiology and pathophysiology have been well established as the enzyme was first identified 80 years ago. And that G6PD has been extensively studied especially with respect to G6PD deficiency ... ... hiện toàn bộ
Tập 64 Số 5 - Trang 362-369 - 2012
From JNK to Pay Dirt: Jun Kinases, their Biochemistry, Physiology and Clinical ImportanceAbstract The c‐Jun N‐terminal kinases (JNKs) were originally identified by their ability to phosphorylate c‐Jun in response to UV‐irradiation, but now are recognized as critical regulators of various aspects of mammalian physiology, including: cell proliferation, cell survival, cell death, DNA repair and metabolism. JNK‐mediated phosphorylation enhances the ability ... ... hiện toàn bộ
Tập 57 Số 4-5 - Trang 283-295 - 2005
Antibacterial components of honeyAbstract The antibacterial activity of honey has been known since the 19th century. Recently, the potent activity of honey against antibiotic‐resistant bacteria has further increased the interest for application of honey, but incomplete knowledge of the antibacterial activity is a major obstacle for clinical applicability. The high sugar concentration, hydrogen pero... ... hiện toàn bộ
Tập 64 Số 1 - Trang 48-55 - 2012
Reactive Oxygen Species and Signal TransductionAbstract Increasing evidence suggests a role for intracellular reactive oxygen species (ROS) as mediators of normal and pathological signal transduction pathways. In particular, a growing list of recent reports have demonstrated a rapid and significant increases in intracellular ROS following growth factor or cytokine stimulation. These ROS appear essential for a ho... ... hiện toàn bộ
Tập 52 Số 1 - Trang 3-6 - 2001