NASH: A global health problem Tập 41 Số 7 - Trang 670-674 - 2011
Arun J. Sanyal
Non‐alcoholic fatty liver disease (NAFLD) is a major public health problem both
in the Western world and in the East. This is mainly due to the high prevalence
of the disease and its effects on the individual with NAFLD. In the USA, it is
estimated that approximately a third of the general population has NAFLD.
Increasing age, obesity and the presence of multiple features of metabolic
syndrome, es... hiện toàn bộ
Hiệu quả của rosuvastatin trong điều trị viêm gan nhiễm mỡ không do rượu kèm theo rối loạn lipid máu: Nghiên cứu thí điểm, công khai Dịch bởi AI Tập 42 Số 11 - Trang 1065-1072 - 2012
Hideyuki Hyogo, Tadashi Ikegami, Katsutoshi Tokushige, Etsuko Hashimoto, Kazuo Inui, Yasushi Matsuzaki, Hironori Tokumo, Fumiaki Hino, Susumu Tazuma
Mục tiêu: Statin, một chất ức chế 3‐hydroxy‐3‐methylglutaryl‐coenzyme A
(HMG‐CoA) reductase, được báo cáo có ích trong việc điều trị viêm gan nhiễm mỡ
không do rượu (NASH). Hiện nay, chưa có liệu pháp đã được chứng minh cho NASH.
Trong nghiên cứu này, chúng tôi đã đánh giá hiệu quả của rosuvastatin ở bệnh
nhân NASH có rối loạn lipid máu.Phương pháp: Mười chín bệnh nhân có chẩn đoán
sinh thiết NA... hiện toàn bộ
#Rosuvastatin #Viêm gan nhiễm mỡ không do rượu #Rối loạn lipid máu #Nghiên cứu thí điểm #Sinh thiết mô học
Pathogenesis of alcoholic liver disease Tập 47 Số 1 - Trang 70-79 - 2017
Kazushi Sugimoto, Yoshiyuki Takei
Alcoholic liver disease (ALD) has become one of the most critical health
problems in many countries, including Japan. Liver injury in ALD ranges from
steatosis and steatohepatitis to fibrosis, cirrhosis, and hepatocellular
carcinoma. Many factors are thought to contribute to the development and
progression of ALD, particularly insulin resistance, generation of reactive
oxygen species during alcoho... hiện toàn bộ
Impact of tumor size, number of tumors and neutrophil‐to‐lymphocyte ratio in liver transplantation for recurrent hepatocellular carcinoma Tập 43 Số 7 - Trang 709-716 - 2013
Tomoharu Yoshizumi, Toru Ikegami, Shohei Yoshiya, Takashi Motomura, Yohei Mano, Jun Muto, Tetsuo Ikeda, Yuji Soejima, Ken Shirabe, Yoshihiko Maehara
AimHepatocellular carcinoma (HCC) is primarily treated with hepatic resection
and/or locoregional therapy. When HCC recurs and further treatment is no longer
possible owing to poor liver function, liver transplantation (LT) or
living‐donor LT (LDLT) is considered. The aim of this study was to clarify risk
factors for tumor recurrence after LDLT in patients with recurrent
HCC.MethodsThe study compr... hiện toàn bộ
Efficacy of pitavastatin for the treatment of non‐alcoholic steatohepatitis with dyslipidemia: An open‐label, pilot study Tập 41 Số 11 - Trang 1057-1065 - 2011
Hideyuki Hyogo, Tadashi Ikegami, Katsutoshi Tokushige, Etsuko Hashimoto, Kazuo Inui, Yasushi Matsuzaki, Hironori Tokumo, Fumiaki Hino, Susumu Tazuma
Aim: Non‐alcoholic fatty liver disease (NAFLD) that encompasses a spectrum of
liver disorders characterized by simple steatosis, non‐alcoholic steatohepatitis
(NASH) through cirrhosis, is becoming an important chronic liver disease in
Japan. Currently, there is no proven therapy for NASH. In this study, we
assessed the efficacy of statin therapy in NASH patients with
dyslipidemia.Methods: Twenty... hiện toàn bộ
Carnosic acid prevents obesity and hepatic steatosis in ob/ob mice Tập 41 Số 1 - Trang 87-92 - 2011
Ting Wang, Yasuhiro Takikawa, Takumi Satoh, Yoshichika Yoshioka, Kunio Kosaka, Yoshinori Tatemichi, Kazuyuki Suzuki
Aim: Carnosic acid (CA) inhibits adipogenesis in vitro. The present study
evaluated the therapeutic effects of CA in ob/ob mice.Methods: The experimental
animals were given a standard chow diet with or without CA for 5 weeks.
Bodyweight gain and food intake were measured during this period. Magnetic
resonance imaging analysis, histological examination, serum chemistry analysis
and intraperitonea... hiện toàn bộ
Microbubble-induced increase in ablation of liver tumors by high-intensity focused ultrasound Tập 36 - Trang 308-314 - 2006
Kazuyuki Hanajiri, Toshiyuki Maruyama, Yukio Kaneko, Hiroshi Mitsui, Shunsuke Watanabe, Masataka Sata, Ryozo Nagai, Takeshi Kashima, Junji Shibahara, Masao Omata, Yoichiro Matsumoto