Circular RNAs in heart failureEuropean Journal of Heart Failure - Tập 19 Số 6 - Trang 701-709 - 2017
Yvan Devaux, Esther E. Creemers, Reinier A. Boon, Stanislas Werfel, Thomas Thum, Stefan Engelhardt, Stefanie Dimmeler, Iain Squire
AbstractCardiovascular disease, and particularly heart failure, is still a
serious health care issue for which novel treatments and biomarkers are needed.
The RNA family comprises different subgroups, among which the small‐sized
microRNAs and the larger long non‐coding RNAs have shown some potential to aid
in moving personalized health care of heart failure patients a step forward.
Here, members o... hiện toàn bộ
Sympathetic activation in congestive heart failure: Reproducibility of neuroadrenergic markersEuropean Journal of Heart Failure - Tập 10 Số 12 - Trang 1186-1191 - 2008
Guıdo Grassı, G. Bolla, Fosca Quartı-Trevano, Francesca Arenare, Gianmaria Brambilla, Giuseppe Mancia
AbstractObjective:To assess the reproducibility of the two markers of adrenergic
drive, venous plasma norepinephrine (NE) and efferent postganglionic muscle
sympathetic nerve activity (MSNA), in reflecting the sympathetic activation
characterizing congestive heart failure (CHF).Methods and measurements:In 19 CHF
male normotensive patients (mean age: 53.0±2.1 years, NYHA classes II and III,
left ve... hiện toàn bộ
Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of CardiologyEuropean Journal of Heart Failure - Tập 21 Số 3 - Trang 272-285 - 2019
Rudolf A. de Boer, Mihai Gheorghiade, Johann Bauersachs, Dirk L. Brutsaert, John G.F. Cleland, Javier Dı́ez, Xiao-Jun Du, Paul Ford, Frank R. Heinzel, Kenneth E. Lipson, Theresa A. McDonagh, Natalia López‐Andrés, Ida G. Lunde, Alexander R. Lyon, Piero Pollesello, Sanjay Prasad, Carlo G. Tocchetti, Manuel Mayr, Joost P. G. Sluijter, Thomas Thum, Carsten Tschöpe, Faı̈ez Zannad, Wolfram‐Hubertus Zimmermann, Frank Ruschitzka, Gerasimos Filippatos, Merry L. Lindsey, Christoph Maack, Stéphane Heymans
AbstractFibrosis is a pivotal player in heart failure development and
progression. Measurements of (markers of) fibrosis in tissue and blood may help
to diagnose and risk stratify patients with heart failure, and its treatment may
be effective in preventing heart failure and its progression. A lack of
pathophysiological insights and uniform definitions has hampered the research in
fibrosis and hea... hiện toàn bộ
Epidemiology and clinical course of heart failure with preserved ejection fractionEuropean Journal of Heart Failure - Tập 13 Số 1 - Trang 18-28 - 2011
Carolyn S.P. Lam, Erwan Donal, Elisabeth Kraigher‐Krainer, Ramachandran S. Vasan
Heart failure with preserved ejection fraction (HFPEF) is increasingly
recognized as a major public health problem worldwide. Significant advances have
been made in our understanding of the epidemiology of HFPEF over the past two
decades, with the publication of numerous population‐based epidemiological
studies, large heart failure registries, and randomized clinical trials. These
recent studies h... hiện toàn bộ
Circulating heart failure biomarkers beyond natriuretic peptides: review from the Biomarker Study Group of the Heart Failure Association (HFA), European Society of Cardiology (ESC)European Journal of Heart Failure - Tập 23 Số 10 - Trang 1610-1632 - 2021
Wouter C. Meijers, Antoni Bayés‐Genís, Alexandre Mebazaa, Johann Bauersachs, John G.F. Cleland, Andrew J.S. Coats, James L. Januzzi, Alan S. Maisel, Kenneth McDonald, Thomas Mueller, Mark Richards, Petar Seferović, Christian Mueller, Rudolf A. de Boer
AbstractNew biomarkers are being evaluated for their ability to advance the
management of patients with heart failure. Despite a large pool of interesting
candidate biomarkers, besides natriuretic peptides virtually none have succeeded
in being applied into the clinical setting. In this review, we examine the most
promising emerging candidates for clinical assessment and management of patients
wit... hiện toàn bộ
Intramyocardial inflammation predicts adverse outcome in patients with cardiac AL amyloidosisEuropean Journal of Heart Failure - Tập 20 Số 4 - Trang 751-757 - 2018
Christine S. Siegismund, Felicitas Escher, Dirk Laßner, Uwe Kühl, Ulrich Gross, Friedrich Fruhwald, Philip Wenzel, Thomas Münzel, Norbert Frey, Reinhold P. Linke, Heinz‐Peter Schultheiß
AimsTo evaluate the influence of endomyocardial biopsy (EMB)‐proven
intramyocardial inflammation on mortality in patients with cardiac transthyretin
amyloid (ATTR) or amyloid light‐chain (AL) amyloidosis.Methods and resultsWe
included 54 consecutive patients (mean age 68.83 ± 9.59 years; 45 men) with
EMB‐proven cardiac amyloidosis. We followed up patients from first diagnostic
biopsy to as long as... hiện toàn bộ
Long‐term outcome and its predictors in giant cell myocarditisEuropean Journal of Heart Failure - Tập 18 Số 12 - Trang 1452-1458 - 2016
Kaj Ekström, Jukka Lehtonen, Riina Kandolin, Anne Räisänen‐Sokolowski, Kaisa Salmenkivi, Markku Kupari
AbstractAimsThere are no studies focusing on prognostic factors in giant cell
myocarditis (GCM). We aimed to identify predictors of transplant‐free survival
in GCM.Methods and resultsWe analysed the details of 46 patients with GCM (31
women, mean age 51 ± 12 years) seen at our hospital since 1991 and followed for
the occurrence of cardiac death or transplantation till May 2015. The
association of ... hiện toàn bộ