European Journal of Heart Failure

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Sympathetic activation in congestive heart failure: Reproducibility of neuroadrenergic markers
European Journal of Heart Failure - Tập 10 Số 12 - Trang 1186-1191 - 2008
Guıdo Grassı, G. Bolla, Fosca Quartı-Trevano, Francesca Arenare, Gianmaria Brambilla, Giuseppe Mancia
AbstractObjective:To assess the reproducibility of the two markers of adrenergic drive, venous plasma norepinephrine (NE) and efferent postganglionic muscle sympathetic nerve activity (MSNA), in reflecting the sympathetic activation characterizing congestive heart failure (CHF).Methods and...... hiện toàn bộ
Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology
European Journal of Heart Failure - Tập 21 Số 3 - Trang 272-285 - 2019
Rudolf A. de Boer, Mihai Gheorghiade, Johann Bauersachs, Dirk L. Brutsaert, John G.F. Cleland, Javier Dı́ez, Xiao-Jun Du, Paul Ford, Frank R. Heinzel, Kenneth E. Lipson, Theresa A. McDonagh, Natalia López‐Andrés, Ida G. Lunde, Alexander R. Lyon, Piero Pollesello, Sanjay Prasad, Carlo G. Tocchetti, Manuel Mayr, Joost P. G. Sluijter, Thomas Thum, Carsten Tschöpe, Faı̈ez Zannad, Wolfram‐Hubertus Zimmermann, Frank Ruschitzka, Gerasimos Filippatos, Merry L. Lindsey, Christoph Maack, Stéphane Heymans
AbstractFibrosis is a pivotal player in heart failure development and progression. Measurements of (markers of) fibrosis in tissue and blood may help to diagnose and risk stratify patients with heart failure, and its treatment may be effective in preventing heart failure and its progression. A lack of pathophysiological insights and uniform definitions has hampered...... hiện toàn bộ
Epidemiology and clinical course of heart failure with preserved ejection fraction
European Journal of Heart Failure - Tập 13 Số 1 - Trang 18-28 - 2011
Carolyn S.P. Lam, Erwan Donal, Elisabeth Kraigher‐Krainer, Ramachandran S. Vasan
Heart failure with preserved ejection fraction (HFPEF) is increasingly recognized as a major public health problem worldwide. Significant advances have been made in our understanding of the epidemiology of HFPEF over the past two decades, with the publication of numerous population‐based epidemiological studies, large heart failure registries, and randomized clinical trials. These recent s...... hiện toàn bộ
The strengths and limitations of E/e' in heart failure with preserved ejection fraction
European Journal of Heart Failure - Tập 20 Số 9 - Trang 1312-1314 - 2018
Masaru Obokata, Barry A. Borlaug
Time to end the war on cell therapy
European Journal of Heart Failure - Tập 22 Số 5 - Trang 893-897 - 2020
Roberto Bolli, Arunpreet Kahlon
Long‐term prognosis, subsequent pregnancy, contraception and overall management of peripartum cardiomyopathy: practical guidance paper from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy
European Journal of Heart Failure - Tập 20 Số 6 - Trang 951-962 - 2018
Karen Sliwa, Mark C. Petrie, Denise Hilfiker‐Kleiner, Alexandre Mebazaa, Alice M. Jackson, Mark R. Johnson, Peter van der Meer, Amam Mbakwem, Johann Bauersachs
Peripartum cardiomyopathy is an idiopathic cardiomyopathy presenting with heart failure secondary to left ventricular systolic dysfunction towards the end of pregnancy or in the months following delivery, where no other cause for heart failure is identified. Outcome varies from full recovery to residual left ventricular systolic dysfunction and even death. Many women return to their physic...... hiện toàn bộ
The Dapagliflozin And Prevention of Adverse‐outcomes in Heart Failure (DAPA‐HF) trial: baseline characteristics
European Journal of Heart Failure - Tập 21 Số 11 - Trang 1402-1411 - 2019
John J.V. McMurray, David L. DeMets, Silvio E. Inzucchi, Lars Køber, Mikhail Kosiborod, Anna Maria Langkilde, Felipe A. Martínez, Olof Bengtsson, Piotr Ponikowski, Marc S. Sabatine, Mikaela Sjöstrand, Scott D. Solomon
BackgroundThe aims of this study were to: (i) report the baseline characteristics of patients enrolled in the Dapagliflozin And Prevention of Adverse‐outcomes in Heart Failure (DAPA‐HF) trial, (ii) compare DAPA‐HF patients to participants in contemporary heart failure (HF) registries and in other recent HF trials, and (iii) compare individuals with diabet...... hiện toàn bộ
Prevalence and prognostic impact of the coexistence of multiple frailty domains in elderly patients with heart failure: the FRAGILE‐HF cohort study
European Journal of Heart Failure - Tập 22 Số 11 - Trang 2112-2119 - 2020
Yuya Matsue, Kentaro Kamiya, Hiroshi Saitô, Kazuya Saito, Yuki Ogasahara, Emi Maekawa, Masaaki Konishi, Takeshi Kitai, K. Iwata, Kentaro Jujo, Hiroshi Wada, Takatoshi Kasai, Hirofumi Nagamatsu, Tetsuya Ozawa, Katsuya Izawa, Shuhei Yamamoto, Naoki Aizawa, Ryusuke Yonezawa, Kazuhiro Oka, Shin‐ichi Momomura, Nobuyuki Kagiyama
AbstractAimsTo describe the prevalence, overlap, and prognostic implications of physical and social frailties and cognitive dysfunction in hospitalized elderly patients with heart failure.Methods and resultsThe FRAGILE‐HF study was a prospective multicentre cohort stud...... hiện toàn bộ
Clinical correlates and outcome associated with changes in 6‐minute walking distance in patients with heart failure: findings from the BIOSTAT‐CHF study
European Journal of Heart Failure - Tập 21 Số 2 - Trang 218-226 - 2019
João Pedro Ferreira, Marco Metra, Stefan D. Anker, Kenneth Dickstein, Chim C. Lang, Leong L. Ng, Nilesh J. Samani, John G.F. Cleland, Dirk J. van Veldhuisen, Adriaan A. Voors, Faı̈ez Zannad
AbstractBackgroundThe 6‐minute walk test (6MWT) is a simple and inexpensive way of measuring exercise capacity in patients with heart failure (HF) that predicts morbidity and mortality. However, there are few reports from large multicentre cohorts assessing the predictive value of baseline and changing walk distance.... hiện toàn bộ
AKT signalling in the failing heart
European Journal of Heart Failure - Tập 13 Số 8 - Trang 825-829 - 2011
Antoine H. Chaanine, Roger J. Hajjar
AKT is a serine/threonine protein kinase, also known as protein kinase B, which regulates cardiac growth, myocardial angiogenesis, glucose metabolism, and cell death in cardiac myocytes. AKT is activated by its phosphorylation at Thr 308 and ser 473 by PDK1 and mTORC2, respectively, in response to trophic stimuli such as insulin and insulin growth factor. c‐Jun N‐Terminal Kinases (JNKs) ph...... hiện toàn bộ
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