Epidemiology and clinical course of heart failure with preserved ejection fraction

European Journal of Heart Failure - Tập 13 Số 1 - Trang 18-28 - 2011
Carolyn S.P. Lam1, Erwan Donal2, Elisabeth Kraigher‐Krainer3, Ramachandran S. Vasan4,1
1National Heart, Lung, and Blood Institute's Framingham Heart Study, 73 Mt Wayte Ave., Framingham, MA, 01702 USA
2Department of Cardiology, Rennes University Hospital, Rennes, France
3Department of Cardiology, Medical University of Graz, Graz, Austria
4Cardiology Section and section of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, MA, USA

Tóm tắt

Heart failure with preserved ejection fraction (HFPEF) is increasingly recognized as a major public health problem worldwide. Significant advances have been made in our understanding of the epidemiology of HFPEF over the past two decades, with the publication of numerous population‐based epidemiological studies, large heart failure registries, and randomized clinical trials. These recent studies have provided detailed characterization of larger numbers of patients with HFPEF than ever before. This review summarizes the state of current knowledge with regards to the disease burden, patient characteristics, clinical course, and outcomes of HFPEF. Despite the wealth of available data, substantive gaps in knowledge were identified. These gaps represent opportunities for further research in HFPEF, a syndrome that is clearly a rising societal burden and that is associated with substantial morbidity and mortality.

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European Journal of Heart Failure

Tập 13 Số 1

18-28

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