State of the art in selection of variables and functional forms in multivariable analysis—outstanding issues Tập 4 Số 1 - 2020
Willi Sauerbrei, Aris Perperoglou, Matthias Schmid, Michal Abrahamowicz, Heiko Becher, Harald Binder, Daniela Dunkler, Frank E. Harrell, Patrick Royston, Georg Heinze
AbstractBackgroundHow to select variables and identify functional forms for continuous variables is a key concern when creating a multivariable model. Ad hoc ‘traditional’ approaches to variable selection have been in use for at least 50 years. Similarly, methods for determining functional forms for continuous variables were first...... hiện toàn bộ
Continual updating and monitoring of clinical prediction models: time for dynamic prediction systems? Tập 5 Số 1 - 2021
David Jenkins, Glen P. Martin, Matthew Sperrin, Richard D Riley, Thomas P A Debray, Gary S. Collins, Niels Peek
AbstractClinical prediction models (CPMs) have become fundamental for risk stratification across healthcare. The CPM pipeline (development, validation, deployment, and impact assessment) is commonly viewed as a one-time activity, with model updating rarely considered and done in a somewhat ad hoc manner. This fails to address the fact that the performance of a CPM ...... hiện toàn bộ
A generic nomogram for multinomial prediction models: theory and guidance for construction Tập 1 - Trang 1-7 - 2017
Maarten van Smeden, Joris AH de Groot, Stavros Nikolakopoulos, Loes CM Bertens, Karel GM Moons, Johannes B. Reitsma
The use of multinomial logistic regression models is advocated for modeling the associations of covariates with three or more mutually exclusive outcome categories. As compared to a binary logistic regression analysis, the simultaneous modeling of multiple outcome categories using a multinomial model often better resembles the clinical setting, where a physician typically must distinguish between ...... hiện toàn bộ
Predictors of the effects of treatment for shoulder pain: protocol of an individual participant data meta-analysis Tập 3 Số 1 - 2019
D.A.W.M. van der Windt, Danielle L. Burke, Opeyemi Babatunde, Miriam Hattle, Cliona McRobert, Chris Littlewood, Gwenllian Wynne‐Jones, Linda S Chesterton, Geert J. M. G. van der Heijden, Jan C. Winters, Daniel I. Rhon, Kim L Bennell, Edward Roddy, Carl Heneghan, David Beard, Jonathan Rees, Richard D Riley
A prediction model for the decline in renal function in people with type 2 diabetes mellitus: study protocol Tập 5 Số 1 - 2021
Mariella Gregorich, Andreas Heinzel, Michael Kammer, Heike Meiselbach, Carsten A. Böger, Kai‐Uwe Eckardt, Gert Mayer, Georg Heinze, Rainer Oberbauer
Abstract
Background
Chronic kidney disease (CKD) is a well-established complication in people with diabetes mellitus. Roughly one quarter of prevalent patients with diabetes exhibit a CKD stage of 3 or higher and the individual course of progression is highly variable. Therefore, there is a clear ne...... hiện toàn bộ