Diagnostic and Prognostic Research

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A study protocol for the development and internal validation of a multivariable prognostic model to determine lower extremity muscle injury risk in elite football (soccer) players, with further exploration of prognostic factors
Diagnostic and Prognostic Research - Tập 3 - Trang 1-13 - 2019
Tom Hughes, Richard Riley, Jamie C. Sergeant, Michael J. Callaghan
Indirect muscle injuries (IMIs) are a considerable burden to elite football (soccer) teams, and prevention of these injuries offers many benefits. Preseason medical, musculoskeletal and performance screening (termed periodic health examination (PHE)) can be used to help determine players at risk of injuries such as IMIs, where identification of PHE-derived prognostic factors (PF) may inform IMI pr... hiện toàn bộ
Prognosis and prediction of antibiotic benefit in adults with clinically diagnosed acute rhinosinusitis: an individual participant data meta-analysis
Diagnostic and Prognostic Research - - 2023
Jeroen Hoogland, Toshihiko Takada, Maarten van Smeden, Maroeska M. Rovers, An I. de Sutter, Daniel Merenstein, Laurent Kaiser, Helena Liira, Paul Little, Heiner C. Bucher, Karel G. M. Moons, Johannes B. Reitsma, Roderick P. Venekamp
A previous individual participant data meta-analysis (IPD-MA) of antibiotics for adults with clinically diagnosed acute rhinosinusitis (ARS) showed a marginal overall effect of antibiotics, but was unable to identify patients that are most likely to benefit from antibiotics when applying conventional (i.e. univariable or one-variable-at-a-time) subgroup analysis. We updated the systematic review a... hiện toàn bộ
So sánh các chiến lược cập nhật động cho các mô hình dự đoán lâm sàng Dịch bởi AI
Diagnostic and Prognostic Research - Tập 5 - Trang 1-10 - 2021
Erin M. Schnellinger, Wei Yang, Stephen E. Kimmel
Các mô hình dự đoán đóng vai trò quan trọng trong nhiều quyết định y tế, nhưng hiệu suất của chúng thường suy giảm theo thời gian. Nhiều chiến lược cập nhật theo thời gian rời rạc đã được đề xuất trong tài liệu, bao gồm điều chỉnh lại mô hình và sửa đổi. Tuy nhiên, các chiến lược này chưa được so sánh trong bối cảnh cập nhật động. Chúng tôi đã sử dụng dữ liệu sống sau phẫu thuật ghép phổi trong gi... hiện toàn bộ
#cập nhật động #mô hình dự đoán lâm sàng #Điểm Brier #điều chỉnh mô hình #dữ liệu sống sau phẫu thuật ghép
Prognostic factors for change in memory test performance after memory training in healthy older adults: a systematic review and outline of statistical challenges
Diagnostic and Prognostic Research - Tập 4 - Trang 1-23 - 2020
Mandy Roheger, Ann-Kristin Folkerts, Fabian Krohm, Nicole Skoetz, Elke Kalbe
The goal is to investigate prognostic factors for change in memory test performance in healthy older adults and to report and discuss the different statistical procedures used for investigating this topic in the literature. Prognostic factors were here understood as any measures that were investigated to estimate change in memory test performance. MEDLINE, Web of Science Core Collection, CENTRAL, ... hiện toàn bộ
TOMAS-R: A template to identify and plan analysis for clinically important variation and multiplicity in diagnostic test accuracy systematic reviews
Diagnostic and Prognostic Research - Tập 6 Số 1
Susan Mallett, Jacqueline Dinnes, Yemisi Takwoingi, Lavinia Ferrante di Ruffano
AbstractThe Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy (DTA) provides guidance on important aspects of conducting a test accuracy systematic review. In this paper we present TOMAS-R (Template of Multiplicity and Analysis in Systematic Reviews), a structured template to use in conjunction with current Cochrane DTA guidance, to help identify complexities in the review quest... hiện toàn bộ
Development of a clinical prediction rule for sepsis in primary care: protocol for the TeSD-IT study
Diagnostic and Prognostic Research - Tập 4 - Trang 1-9 - 2020
Feike J. Loots, Rogier Hopstaken, Kevin Jenniskens, Geert W. J. Frederix, Alma C. van de Pol, Ann Van den Bruel, Jan Jelrik Oosterheert, Arthur R. H. van Zanten, Marleen Smits, Theo J. M. Verheij
Early recognition and treatment of sepsis is crucial to prevent detrimental outcomes. General practitioners (GPs) are often the first healthcare providers to encounter seriously ill patients. The aim of this study is to assess the value of clinical information and additional tests to develop a clinical prediction rule to support early diagnosis and management of sepsis by GPs. We will perform a di... hiện toàn bộ
The calibrated model-based concordance improved assessment of discriminative ability in patient clusters of limited sample size
Diagnostic and Prognostic Research - Tập 3 - Trang 1-13 - 2019
David van Klaveren, Ewout W. Steyerberg, Mithat Gönen, Yvonne Vergouwe
Discriminative ability is an important aspect of prediction model performance, but challenging to assess in clustered (e.g., multicenter) data. Concordance (c)-indexes may be too extreme within small clusters. We aimed to define a new approach for the assessment of discriminative ability in clustered data. We assessed discriminative ability of a prediction model for the binary outcome mortality af... hiện toàn bộ
Development and validation of clinical prediction models to risk stratify patients presenting with small pulmonary nodules: a research protocol
Diagnostic and Prognostic Research - Tập 2 Số 1 - Trang 1-6 - 2018
Oke, Jason L., Pickup, Lyndsey C., Declerck, Jérôme, Callister, Matthew E., Baldwin, David, Gustafson, Jennifer, Peschl, Heiko, Ather, Sarim, Tsakok, Maria, Exell, Alan, Gleeson, Fergus
Lung cancer is a common cancer, with over 1.3 million cases worldwide each year. Early diagnosis using computed tomography (CT) screening has been shown to reduce mortality but also detect non-malignant nodules that require follow-up scanning or alternative methods of investigation. Practical and accurate tools that can predict the probability that a lung nodule is benign or malignant will help re... hiện toàn bộ
The Brier score does not evaluate the clinical utility of diagnostic tests or prediction models
Diagnostic and Prognostic Research - Tập 1 - Trang 1-7 - 2017
Melissa Assel, Daniel D. Sjoberg, Andrew J. Vickers
A variety of statistics have been proposed as tools to help investigators assess the value of diagnostic tests or prediction models. The Brier score has been recommended on the grounds that it is a proper scoring rule that is affected by both discrimination and calibration. However, the Brier score is prevalence dependent in such a way that the rank ordering of tests or models may inappropriately ... hiện toàn bộ
Quality and transparency of reporting derivation and validation prognostic studies of recurrent stroke in patients with TIA and minor stroke: a systematic review
Diagnostic and Prognostic Research - Tập 6 - Trang 1-13 - 2022
Kasim E. Abdulaziz, Jeffrey J. Perry, Krishan Yadav, Dar Dowlatshahi, Ian G. Stiell, George A. Wells, Monica Taljaard
Clinical prediction models/scores help clinicians make optimal evidence-based decisions when caring for their patients. To critically appraise such prediction models for use in a clinical setting, essential information on the derivation and validation of the models needs to be transparently reported. In this systematic review, we assessed the quality of reporting of derivation and validation studi... hiện toàn bộ
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