Current Oncology
SCOPUS (1998-2023)SCIE-ISI
1718-7729
1198-0052
Canada
Cơ quản chủ quản: MDPI , Multidisciplinary Digital Publishing Institute (MDPI)
Lĩnh vực:
Oncology
Các bài báo tiêu biểu
A Review of Cancer Immunotherapy: From the Past, to the Present, to the FutureCompared with previous standards of care (including chemotherapy, radiotherapy, and surgery), cancer immunotherapy has brought significant improvements for patients in terms of survival and quality of life. Immunotherapy has now firmly established itself as a novel pillar of cancer care, from the metastatic stage to the adjuvant and neoadjuvant settings in numerous cancer types. In this re... ... hiện toàn bộ
Tập 27 Số 12 - Trang 87-97
Immune Checkpoint Inhibitors in Cancer TherapyThe discovery of immune checkpoint proteins such as PD-1/PDL-1 and CTLA-4 represents a significant breakthrough in the field of cancer immunotherapy. Therefore, humanized monoclonal antibodies, targeting these immune checkpoint proteins have been utilized successfully in patients with metastatic melanoma, renal cell carcinoma, head and neck cancers and non-small lung cancer. The US FDA has... ... hiện toàn bộ
Tập 29 Số 5 - Trang 3044-3060
Nonsurgical Treatment of Recurrent GlioblastomaStandard treatment for glioblastoma multiforme is surgery followed by radiotherapy and chemotherapy, generally with temozolomide. However, disease recurs in almost all patients. Diagnosis of progression is complex given the possibility of pseudoprogression. The Response Assessment in Neuro-Oncology criteria increase the sensitivity for detecting progression. Most patients will not be candi... ... hiện toàn bộ
Tập 22 Số 4 - Trang 273-281
Survival of Patients with Non-Small-Cell Lung Cancer after a Diagnosis of Brain MetastasesBackground: The prognosis of patients with brain metastases from non-small-cell lung cancer (NSCLC) is poor. However, some reports suggest that patients with brain metastases at the time of initial diagnosis have a more favourable survival than do patients with advanced NSCLC without brain metastases. Methods: In a retrospective cohort of all new lung cancer patients seen at a Canadian ter... ... hiện toàn bộ
Tập 20 Số 4 - Trang 300-306
Treatment Paradigms for Patients with Metastatic Non-Small-Cell Lung Cancer: First-, Second-, and Third-LineMetastatic non-small-cell lung cancer (NSCLC) is the leading cause of cancer mortality in Canada. Although treatment outcomes in advanced disease remain modest, with paradigm shifts in the approach to treatment, they are steadily improving. Customizing treatment based on histology and molecular typing has become the standard of care. EGFR genotyping and pathology subtyping should be consid... ... hiện toàn bộ
Tập 19 Số 11 - Trang 52-58
Multidisciplinary Management of Cancer Patients: Chasing a Shadow or Real Value? An Overview of the LiteraturePurpose: Multidisciplinary cancer conferences (mccs) are designed to optimize patient outcomes. It appears intuitive that mccs are essential to clinical decision-making and patient management; however, it is unclear whether that belief is supported by evidence. Our objectives were to assess the currently published literature addressing the impact of mccs on clinical decision-making and pat... ... hiện toàn bộ
Tập 19 Số 4 - Trang 232-238
Cancer and Venous Thromboembolic Disease: From Molecular Mechanisms to Clinical ManagementVenous thromboembolism (VTE) represents a major challenge in the management of patients with cancer. The malignant phenotype is associated with derangements in the coagulation cascade that can manifest as thrombosis, hemorrhage, or disseminated intravascular coagulation. The risk of VTE is increased by a factor of approximately 6 in patients with cancer compared with non-cancer patients, a... ... hiện toàn bộ
Tập 21 Số 3 - Trang 134-143
A Systematic Review of Acupuncture for Chemotherapy-Induced Peripheral NeuropathyObjectives: In cancer patients, chemotherapy-induced peripheral neuropathy (cipn) is a common complication, characterized by pain, loss of sensation, and numbness. Medical treatment for peripheral neuropathies has been shown to be ineffective for cipn. Acupuncture has been shown to be safe and effective in treating cancer-related symptoms and other peripheral neuropathies. For the present ... ... hiện toàn bộ
Tập 26 Số 2 - Trang 4261
ALK Inhibitors, Resistance Development, Clinical TrialsThe treatment of advanced non-small-cell lung cancer (NSCLC) has undergone a paradigm shift since the early 2000s. The identification of molecular subtypes of the disease, based on oncogenic drivers, has led to the development of personalized medicine and the ability to deliver molecularly targeted therapies to patients. In the 10 years that have elapsed since the discovery of the ALK gene... ... hiện toàn bộ
Tập 25 Số 11 - Trang 59-67
Association of Preoperative Anemia and Perioperative Allogenic Red Blood Cell Transfusion with Oncologic Outcomes in Patients with Nonmetastatic Colorectal CancerBackground: We investigated whether preoperative anemia and perioperative blood transfusion (PBT) are associated with overall survival and recurrence-free survival in patients with nonmetastatic colorectal cancer. Methods: From 1 January 2009 to 31 December 2014, 1003 patients with primary colorectal cancer were enrolled in the study. Perioperative clinical and oncologic outcomes were anal... ... hiện toàn bộ
Tập 26 Số 3 - Trang 357-366