Current Oncology

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Lazarus-Type Tumour Response to Therapy with Nivolumab for Sarcomatoid Carcinomas of the Lung
Current Oncology - Tập 26 Số 2 - Trang 270-273
Christian Roesel, Kato Kambartel, Uldis Kopeika, Arvids Berzins, Thomas Voshaar, Thomas Krbek
Pulmonary sarcomatoid carcinoma (PSC) is a rare subtype of non-small-cell lung carcinoma with a poor prognosis and poor response to chemotherapy and radiotherapy. A previous study reported that psc expresses high levels of PD-L1, suggesting the potential efficacy of immune checkpoint inhibitors in these tumours. We report 2 cases of patients with a lung sarcomatoid carcinoma. Both patients...... hiện toàn bộ
Evaluation of a routine screening program with tuberculin skin testing on rates of detection of latent tuberculosis infection and prevention of active tuberculosis in patients with multiple myeloma at a Canadian cancer centre
Current Oncology - Tập 27 Số 3 - Trang e246 - 2020
M Gitman, J Vu, T Nguyen, C Chen, C Rotstein
Lenalidomide in Multiple Myeloma—A Practice Guideline
Current Oncology - Tập 20 Số 2 - Trang 136-149
C. Chen, Fulvia Baldassarre, Sindu Kanjeekal, Jordan A. Herst, Lisa K. Hicks, Matthew C. Cheung
Background: Promising new drugs such as lenalidomide, an immunomodulatory agent, are available for the treatment of multiple myeloma. We describe the process of creating a provincial guideline for the use of lenalidomide, alone or in combination with other drugs, in relapsed, refractory, or newly diagnosed disease (including smoldering and symptomatic patients, and candidates and non-candi...... hiện toàn bộ
Association of Preoperative Anemia and Perioperative Allogenic Red Blood Cell Transfusion with Oncologic Outcomes in Patients with Nonmetastatic Colorectal Cancer
Current Oncology - Tập 26 Số 3 - Trang 357-366
Hye-Jeong Kwon, B. R. Kim, Yong Wook Kim
Background: We investigated whether preoperative anemia and perioperative blood transfusion (PBT) are associated with overall survival and recurrence-free survival in patients with nonmetastatic colorectal cancer. Methods: From 1 January 2009 to 31 December 2014, 1003 patients with primary colorectal cancer were enrolled in the study. Perioperative clinical and oncologic outcomes were anal...... hiện toàn bộ
Strategies for the Delay of Surgery in the Management of Resectable Hepatobiliary Malignancies during the COVID-19 Pandemic
Current Oncology - Tập 27 Số 5 - Trang 501-511
Sonya Bennett, Kjetil Søreide, Sepideh Gholami, Patrick Pessaux, Catherine Teh, Eva Segelov, Hagen F. Kennecke, Hans Prenen, Sten Myrehaug, Dario Callegaro, Julie Hallet
Objective: We aimed to review data about delaying strategies for the management of hepatobiliary cancers requiring surgery during the covid-19 pandemic. Background: Given the covid-19 pandemic, many jurisdictions, to spare resources, have limited access to operating rooms for elective surgical activity, including cancer, thus forcing deferral or cancellation of cancer surgeries. Surgery fo...... hiện toàn bộ
Survival of Patients with Non-Small-Cell Lung Cancer after a Diagnosis of Brain Metastases
Current Oncology - Tập 20 Số 4 - Trang 300-306
Arwa Ali, John R. Goffin, Andrew Arnold, Peter Ellis
Background: The prognosis of patients with brain metastases from non-small-cell lung cancer (NSCLC) is poor. However, some reports suggest that patients with brain metastases at the time of initial diagnosis have a more favourable survival than do patients with advanced NSCLC without brain metastases. Methods: In a retrospective cohort of all new lung cancer patients seen at a Canadian ter...... hiện toàn bộ
Area-Level Income Disparities in Colorectal Screening in Canada: Evidence to Inform Future Surveillance
Current Oncology - Tập 26 Số 2 - Trang 128-137
Alexandra Blair, Lise Gauvin, Samiratou Ouédraogo, Geetanjali D. Datta
Background: Participation in colorectal screening remains low even in countries with universal health coverage. Area-level determinants of low screening participation in Canada remain poorly understood. Methods: We assessed the association between area-level income and two indicators of colorectal screening (having never been screened, having not been screened recently) by linking census-d...... hiện toàn bộ
Recent Trends in Breast, Cervical, and Colorectal Cancer Screening Test Utilization in Canada, Using Self-Reported Data from 2008 and 2012
Current Oncology - Tập 22 Số 4 - Trang 297-302
Diane Major, David Armstrong, Heather Bryant, Winson Y. Cheung, Kathleen Decker, Gregory Doyle, V. Mai, C. Meg McLachlin, Jin Niu, Jennifer Payne, N. K. Shukla
In Canada, self-reported data from the Canadian Community Health Survey 2008 and 2012 provide an opportunity to examine overall utilization of breast, cervical, and colorectal cancer screening tests for both programmatic and opportunistic screening. Among women 50–74 years of age, utilization of screening mammography was stable (62.0% in 2008 and 63.0% in 2012). Pap test utilization for wo...... hiện toàn bộ
Applications of Artificial Intelligence in Screening, Diagnosis, Treatment, and Prognosis of Colorectal Cancer
Current Oncology - Tập 29 Số 3 - Trang 1773-1795
Hang Qiu, Shuhan Ding, Jianbo Liu, Liya Wang, Xiaodong Wang
Colorectal cancer (CRC) is one of the most common cancers worldwide. Accurate early detection and diagnosis, comprehensive assessment of treatment response, and precise prediction of prognosis are essential to improve the patients’ survival rate. In recent years, due to the explosion of clinical and omics data, and groundbreaking research in machine learning, artificial intelligence (AI) h...... hiện toàn bộ
Treatment Paradigms for Patients with Metastatic Non-Small-Cell Lung Cancer: First-, Second-, and Third-Line
Current Oncology - Tập 19 Số 11 - Trang 52-58
Natasha B. Leighl
Metastatic non-small-cell lung cancer (NSCLC) is the leading cause of cancer mortality in Canada. Although treatment outcomes in advanced disease remain modest, with paradigm shifts in the approach to treatment, they are steadily improving. Customizing treatment based on histology and molecular typing has become the standard of care. EGFR genotyping and pathology subtyping should be consid...... hiện toàn bộ
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