Current Oncology

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Evaluation of a routine screening program with tuberculin skin testing on rates of detection of latent tuberculosis infection and prevention of active tuberculosis in patients with multiple myeloma at a Canadian cancer centre
Current Oncology - Tập 27 Số 3 - Trang e246 - 2020
M Gitman, J Vu, T Nguyen, C Chen, C Rotstein
Advances in the Management of Metastatic Breast Cancer: Options Beyond First-Line Chemotherapy
Current Oncology - Tập 19 Số 2 - Trang 91-105
J-P. Ayoub, S. Verma, S. Verma
This article provides an overview of recent advances in chemotherapy that may be used for the treatment of patients with locally advanced or metastatic breast cancer (mbc). Key phase ii and iii trial data for eribulin mesylate, ixabepilone, and nab-paclitaxel, published since 2006, are discussed on the basis of recency, depth, and quality. Eribulin mesylate is the first monotherapy to sign...... hiện toàn bộ
Area-Level Income Disparities in Colorectal Screening in Canada: Evidence to Inform Future Surveillance
Current Oncology - Tập 26 Số 2 - Trang 128-137
Alexandra Blair, Lise Gauvin, Samiratou Ouédraogo, Geetanjali D. Datta
Background: Participation in colorectal screening remains low even in countries with universal health coverage. Area-level determinants of low screening participation in Canada remain poorly understood. Methods: We assessed the association between area-level income and two indicators of colorectal screening (having never been screened, having not been screened recently) by linking census-d...... hiện toàn bộ
Recent Trends in Breast, Cervical, and Colorectal Cancer Screening Test Utilization in Canada, Using Self-Reported Data from 2008 and 2012
Current Oncology - Tập 22 Số 4 - Trang 297-302
Diane Major, David Armstrong, Heather Bryant, Winson Y. Cheung, Kathleen Decker, Gregory Doyle, V. Mai, C. Meg McLachlin, Jin Niu, Jennifer Payne, N. K. Shukla
In Canada, self-reported data from the Canadian Community Health Survey 2008 and 2012 provide an opportunity to examine overall utilization of breast, cervical, and colorectal cancer screening tests for both programmatic and opportunistic screening. Among women 50–74 years of age, utilization of screening mammography was stable (62.0% in 2008 and 63.0% in 2012). Pap test utilization for wo...... hiện toàn bộ
Survival of Patients with Non-Small-Cell Lung Cancer after a Diagnosis of Brain Metastases
Current Oncology - Tập 20 Số 4 - Trang 300-306
Arwa Ali, John R. Goffin, Andrew Arnold, Peter Ellis
Background: The prognosis of patients with brain metastases from non-small-cell lung cancer (NSCLC) is poor. However, some reports suggest that patients with brain metastases at the time of initial diagnosis have a more favourable survival than do patients with advanced NSCLC without brain metastases. Methods: In a retrospective cohort of all new lung cancer patients seen at a Canadian ter...... hiện toàn bộ
Prostate Cancer Metastasis to the Pituitary Gland Manifesting as Corticosteroid Withdrawal, and the Impact of the Switch from Prednisone to Dexamethasone on Survival Time
Current Oncology - Tập 28 Số 6 - Trang 4291-4297
Okeroghene Ataikiru, Mahmoud Abdelsalam, Mrudula Avileli, T V HYNES
Despite improvements in the diagnosis and treatment of cancers, the incidence of pituitary metastasis has increased. Prostate cancer metastasis to the pituitary, however, is rare, and these tumors usually grow rapidly. They are also more likely to be located in the posterior pituitary, and the presenting symptoms are often nonspecific, which makes early diagnosis challenging. The managemen...... hiện toàn bộ
Multidisciplinary Management of Cancer Patients: Chasing a Shadow or Real Value? An Overview of the Literature
Current Oncology - Tập 19 Số 4 - Trang 232-238
Jennifer Croke, S. El-Sayed
Purpose: Multidisciplinary cancer conferences (mccs) are designed to optimize patient outcomes. It appears intuitive that mccs are essential to clinical decision-making and patient management; however, it is unclear whether that belief is supported by evidence. Our objectives were to assess the currently published literature addressing the impact of mccs on clinical decision-making and pat...... hiện toàn bộ
Factors Affecting Radiotherapy Prescribing Patterns in the Post-Mastectomy Setting
Current Oncology - Tập 25 Số 2 - Trang 146-151
Theodora Koulis, Amit Dang, Caroline Speers, Robert Olson
Background: Radiation therapy (RT) after mastectomy for breast cancer can improve survival outcomes, but has been associated with inferior cosmesis after breast reconstruction. In the literature, RT dose and fractionation schedules are inconsistently reported. We sought to determine the pattern of RT prescribing practices in a provincial RT program for patients treated with mastectomy and ...... hiện toàn bộ
A Systematic Review of Acupuncture for Chemotherapy-Induced Peripheral Neuropathy
Current Oncology - Tập 26 Số 2 - Trang 4261
Kevin Li, Dean Giustini, Dugald Seely
Objectives: In cancer patients, chemotherapy-induced peripheral neuropathy (cipn) is a common complication, characterized by pain, loss of sensation, and numbness. Medical treatment for peripheral neuropathies has been shown to be ineffective for cipn. Acupuncture has been shown to be safe and effective in treating cancer-related symptoms and other peripheral neuropathies. For the present ...... hiện toàn bộ
Immune Checkpoint Inhibitors in Cancer Therapy
Current Oncology - Tập 29 Số 5 - Trang 3044-3060
Yavar Shiravand, Faezeh Khodadadi, Seyyed Mohammad Amin Kashani, Seyed Reza Hosseini‐Fard, Shadi Hosseini, Habib Sadeghirad, Rahul Ladwa, Kenneth V. Honn, Arutha Kulasinghe
The discovery of immune checkpoint proteins such as PD-1/PDL-1 and CTLA-4 represents a significant breakthrough in the field of cancer immunotherapy. Therefore, humanized monoclonal antibodies, targeting these immune checkpoint proteins have been utilized successfully in patients with metastatic melanoma, renal cell carcinoma, head and neck cancers and non-small lung cancer. The US FDA has...... hiện toàn bộ
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