Current Genetics

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Saccharomyces cerevisiaeTSC11/AVO3 participates in regulating cell integrity and functionally interacts with components of the Tor2 complex
Current Genetics - Tập 47 - Trang 273-288 - 2005
Hsiang-Ling Ho, Yu-Shih Shiau, Mei-Yu Chen
Saccharomyces cerevisiae TSC11/AVO3 is an essential gene encoding one component of TORC2, a multi-protein complex of yeast Tor2p that also contains Lst8p, Avo1p, and Avo2p. Despite the proven physical association among TORC2 components, little is known about the functional linkage or cellular pathways these proteins act in. Here, we present genetic data linking the function of TSC11 to the regulat...... hiện toàn bộ
Molecular analysis of a novelSchizosaccharomyces pombe gene containing two RNP consensus-sequence RNA-binding domains
Current Genetics - Tập 29 - Trang 307-315 - 1996
Roger W. VanHoy, Jo Ann Wise
Proteins containing RNP consensus-sequence RNA-binding domains (CS-RBDs) play diverse roles in many aspects of RNA metabolism. Using a PCR strategy, we cloned portions of six newSchizosaccharomyces pombe genes encoding RBD proteins, including a putative homolog of the mammalian splicing factor SAP49. The genomic locus corresponding to a second PCR product, designatedrnp24, was cloned and character...... hiện toàn bộ
A DNA sequence in Saccharomyces exiguus is homologous with the HO gene of Saccharomyces cerevisiae
Current Genetics - Tập 15 - Trang 399-401 - 1989
Taisuke Hisatomi, Michio Tsuboi
The DNA of Saccharomyces exiguus was analyzed by Southern hybridization using cloned MATa, MATα, and HO genes of Saccharomyces cerevisiae as probes. It was shown that S. exiguus has a DNA sequence homologous with the HO gene of S. cerevisiae and that this DNA sequence is on a chromosome of about 940 kb of DNA in S. exiguus. However, there is no DNA sequence in S. exiguus that is homologous with th...... hiện toàn bộ
Cloning and characterisation of the ribosomal RNA genes of the dimorphic yeast, Yarrowia lipolytica
Current Genetics - Tập 10 - Trang 449-452 - 1986
Jeffrey J. Clare, Lance S. Davidow, David C. J. Gardner, Stephen G. Oliver
The ribosomal RNA genes of Yarrowia lipolytica have been identified, both in restriction digests of total genomic DNA and in a pBR322 gene bank, by hybridisation with cloned Saccharomyces cerevisiae rDNA. The Y. lipolytica rDNA repeat unit is 8.9 kb in size and contains the genes for the 25S and 18S, but not the 5S, rRNA species. The number of copies of these repeat units is approx. 50 per haploid...... hiện toàn bộ
Exploiting budding yeast natural variation for industrial processes
Current Genetics - Tập 62 - Trang 745-751 - 2016
Francisco A. Cubillos
For the last two decades, the natural variation of the yeast Saccharomyces cerevisiae has been massively exploited with the aim of understanding ecological and evolutionary processes. As a result, many new genetic variants have been uncovered, providing a large catalogue of alleles underlying complex traits. These alleles represent a rich genetic resource with the potential to provide new strains ...... hiện toàn bộ
POL32, a subunit of the Saccharomyces cerevisiae DNA polymerase δ, defines a link between DNA replication and the mutagenic bypass repair pathway
Current Genetics - Tập 38 - Trang 178-187 - 2000
Meng-Er Huang, Alix de Calignon, Alain Nicolas, Francis Galibert
Pol32 is a subunit of Saccharomyces cerevisiae DNA polymerase δ required in DNA replication and repair. To gain insight into the function of Pol32 and to determine in which repair pathway POL32 may be involved, we extended the analysis of the pol32Δ mutant with respect to UV and methylation sensitivity, UV-induced mutagenesis; and we performed an epistasis analysis of UV sensitivity by combining ...... hiện toàn bộ
AoxA is a major peroxisomal long chain fatty acyl-CoA oxidase required for β-oxidation in A. nidulans
Current Genetics - Tập 56 - Trang 139-150 - 2009
Kathrin Reiser, Meryl A. Davis, Michael J. Hynes
Filamentous fungi can use a variety of fatty acids (FA) as sole carbon and energy sources. Aspergillus nidulans has been shown to possess both peroxisomal and mitochondrial β-oxidation pathways. In these studies, the major peroxisomal long chain fatty acyl coenzyme A oxidase AoxA was identified. AoxA was shown to be localised to peroxisomes and deletion of the aoxA gene leads to reduced growth on ...... hiện toàn bộ
Những biến đổi trong mức độ heteroplasmy và biểu hiện gen ty thể ở một đột biến ty thể của Drosophila subobscura Dịch bởi AI
Current Genetics - Tập 33 - Trang 330-339 - 1998
Nathalie Petit, Sylvie Touraille, Roger Debise, Frederic Morel, Monique Renoux, Pierre Lécher, S. Alziari
Tám mươi phần trăm các phân tử DNA bị mất trong quần thể ty thể của một dòng đột biến trưởng thành của D. subobscura. Cả bộ gen nguyên vẹn và bị mất đều là các đơn vị tự chủ. Mức độ heteroplasmy, vốn thấp hơn trong mô sinh dục, tăng từ trứng chín (60%) đến giai đoạn nhộng thứ ba (83%), và sau đó được duy trì suốt đời của ruồi. Tỷ lệ mtDNA/ DNA hạt nhân trung bình cao gấp đôi ở dòng heteroplasmic s...... hiện toàn bộ
#Drosophila subobscura #mRNA #htDNA #heteroplasmy #đột biến ty thể #tỷ lệ mtDNA/DNA hạt nhân
tRNA wobble-uridine modifications as amino acid sensors and regulators of cellular metabolic state
Current Genetics - Tập 66 Số 3 - Trang 475-480 - 2020
Ritu Gupta, Sunil Laxman
Insertional mutagenesis in Coprinus cinereus : use of a dominant selectable marker to generate tagged, sporulation-defective mutants
Current Genetics - - 1999
W. Jason Cummings, Martina Celerin, Jennifer Crodian, Linda K. Brunick, Miriam E. Zolan
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