Central European Journal of Biology
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Infectious disease — a genetic view
Central European Journal of Biology - Tập 6 - Trang 131-144 - 2011
Genetic analysis of resistance to infectious disease reveals many important cues that have led to new insights into the interaction between pathogen and host. This knowledge might help with a better prognosis for diseases, and to the development of novel therapeutics. This review focuses on genes and loci that control susceptibility to diseases with an important epidemiologic impact, such as AIDS,......
Combined action of X-rays and nonylphenol on mouse sperm
Central European Journal of Biology - Tập 6 - Trang 320-329 - 2011
The aim of this study was to assess the effects of 2-weeks’ X-ray and/or nonylphenol (NP) exposure on male mice’s sperm count and quality. Pzh:SFIS mice were exposed to X-rays (0.05 Gy, 0.10 Gy, 0.20 Gy) or to nonylphenol (25 mg/kg bw, 50 mg/kg bw, 100 mg/kg bw) or to both agents (0.05 Gy + 25 mg/kg bw NP, 0.10 Gy + 50 mg/kg bw NP). At 24 h and 5 weeks after the end of exposure the sperm count, mo......
Daily and seasonal variation in the activity of potential vector mosquitoes
Central European Journal of Biology - Tập 6 - Trang 422-430 - 2011
In the course of season 2010 (May–September), three 2-day trappings of female mosquitoes were carried out at two sites in order to determine the daily activity of the common mosquito species (e.g. species from genus Culex, Aedes, Ochlerotatus, Anopheles, etc.) in the area. CDC light traps filled with CO2 and placed at a height of 1 m were used to trap individuals, and were sampled every 2 h. A tot......
Evaluation of different culture techniques of osteoblasts on 3D scaffolds
Central European Journal of Biology - Tập 5 - Trang 456-465 - 2010
Bones adjust their structure to withstand the mechanical demands they experience. It is suggested that flow-derived shear stress may be the most significant and primary mediator of mechanical stimulation. In this study, we designed and fabricated a fluid flow cell culture system that can load shear stress onto cells cultured on 3D scaffolds. We evaluated the effect of different culture techniques,......
Effect of organic pollutant treatment on the growth of pea and maize seedlings
Central European Journal of Biology - Tập 7 - Trang 159-166 - 2011
This study confirmed the considerable effect of polycyclic aromatic hydrocarbon fluoranthene (FLT; 0.01, 0.1, 1, 4 and 7 mg/l) exposure on the germination of seeds, growth and root morphology of seedlings in Zea mays and Pisum sativum. Seed germination was significantly inhibited at FLT≥0.01 mg/l in maize and at ≥1 mg/l in pea. The amount of released ethylene after 3 days of germination was signif......
Genotyping of Vitis vinifera L. within the Slovak national collection of genetic resources
Central European Journal of Biology - Tập 9 - Trang 761-767 - 2014
Microsatellites were used as a very effective tool for genetic diversity analysis and characterization of 51 grapevine (Vitis vinifera L.) accessions from the national collection of genetic resources. Genetic diversity was relatively high, 8.91 alleles were detected per analysed microsatellite locus in average, and fifty-one accessions were distinguished into 45 groups. Distribution of recent Slov......
Evaluation of Verbascum species and harpagoside in models of acute and chronic inflammation
Central European Journal of Biology - Tập 8 - Trang 186-194 - 2012
Verbascum species are widely used in folk medicine because of their broad range of biological activities. Harpagoside, an iridoid glycoside isolated from some Verbascum plants is known for its anti-inflammatory properties. In the present study, the effect of five extracts of Verbascum species and harpagosides were evaluated in mouse models of acute and chronic inflammation. The re......
Middle-aged rat hippocampus and some early changes accompanying aging
Central European Journal of Biology - Tập 7 - Trang 810-816 - 2012
Studies of the middle-aged hippocampus may clarify the early mechanisms of aging and may lead to timely initiation of treatment for age-related cognitive impairments. Young (2-m/o) and middle aged (15- and 17-m/o) rats were used with the aim to characterize early differences in electrophysiological properties, morphometrical changes and 1H-nuclear magnetic resonance (NMR) metabolite content in the......
A practical introduction to microbial community sequencing
Central European Journal of Biology - Tập 8 - Trang 399-409 - 2013
The use of molecular methods is gaining popularity throughout the field of microbial community ecology studies thanks to their flexibility of application, which ranges from community structure to function and trait determination. Nonetheless, there are environmental microbiologists, who are new in the field and are just starting to get to grips with the genetic tool box. It is for them that this p......
A new perspective on the role of CuZn superoxide dismutase (SOD1)
Central European Journal of Biology - Tập 2 - Trang 337-350 - 2007
The CuZn superoxide dismutase (SOD1), a member of a group of isoenzymes involved in the scavenger of superoxide anions, is a dimeric carbohydrate free protein, mainly localized in the cytosol. The reactive oxygen species (ROS) are involved in many pathophysiological events correlated with mutagenesis, cancer, degenerative processes and aging. In the first part of this mini-review the well known ro......
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