Cell Chemical Biology

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S-Nitrosylation-mediated dysfunction of TCA cycle enzymes in synucleinopathy studied in postmortem human brains and hiPSC-derived neurons
Cell Chemical Biology - Tập 30 - Trang 965-975.e6 - 2023
Paschalis-Thomas Doulias, Hongmei Yang, Alexander Y. Andreyev, Nima Dolatabadi, Henry Scott, Charlene K Raspur, Parth R. Patel, Tomohiro Nakamura, Steven R. Tannenbaum, Harry Ischiropoulos, Stuart A. Lipton
Optimized Streptavidin for Fluorescent Labeling of Biotinylated Targets
Cell Chemical Biology - Tập 24 - Trang 921-922 - 2017
Vesa P. Hytönen
Probing Exchange Units for Combining Iterative and Linear Fungal Nonribosomal Peptide Synthetases
Cell Chemical Biology - Tập 26 - Trang 1526-1534.e2 - 2019
Charlotte Steiniger, Sylvester Hoffmann, Roderich D. Süssmuth
Lenalidomide bypasses CD28 co-stimulation to reinstate PD-1 immunotherapy by activating Notch signaling
Cell Chemical Biology - Tập 29 - Trang 1260-1272.e8 - 2022
Chen-Lu Geng, Jun-Yi Chen, Tian-Yu Song, Jae Hyung Jung, Min Long, Min-Fang Song, Tong Ji, Byung Soh Min, Jin Gu Lee, Bo Peng, Yi-Sheng Pu, Hong-Jie Fan, Piliang Hao, Qi Zhou, Eui-Cheol Shin, Yong Cang
Cutting Choline with Radical Scissors
Cell Chemical Biology - Tập 23 - Trang 1173-1174 - 2016
Joan B. Broderick, James D. Moody
Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samples
Cell Chemical Biology - Tập 29 - Trang 215-225.e5 - 2022
Erin E. Soule, Haixiang Yu, Lyra Olson, Ibtehaj Naqvi, Shekhar Kumar, Sriram Krishnaswamy, Bruce A. Sullenger
Combinatorial Lanthipeptides from a Ruminant Bacterium
Cell Chemical Biology - Tập 23 - Trang 204-205 - 2016
Stefano Donadio
Engineering a Multifunctional Nitroreductase for Improved Activation of Prodrugs and PET Probes for Cancer Gene Therapy
Cell Chemical Biology - Tập 24 - Trang 391 - 2017
Abigail V. Sharrock, Christopher P. Guise, Janine N. Copp, Amir Ashoorzadeh, Elsie M. Williams, David F. Ackerley, Jack U. Flanagan, Alexandra M. Mowday, Jeff B. Smaill, Adam V. Patterson
Gene-directed enzyme-prodrug therapy (GDEPT) is a promising anti-cancer strategy. However, inadequate prodrugs, inefficient prodrug activation, and a lack of non-invasive imaging capabilities have hindered clinical progression. To address these issues, we used a high-throughput Escherichia coli platform to evolve the multifunctional nitroreductase E. coli NfsA for improved activation of a promisin...... hiện toàn bộ
#nitroreductase #PR-104A #GDEPT #BDEPT #directed evolution #PET imaging #nitroimidazole #SOS response #metabolic interference #substrate promiscuity
Repurposing the repurposed: thalidomide analogs as immune stimulants to overcome T cell exhaustion
Cell Chemical Biology - Tập 29 - Trang 1245-1247 - 2022
Mikołaj Słabicki, Adam S. Sperling
A BAF’ling Approach to Curing HIV
Cell Chemical Biology - Tập 25 - Trang 1441-1442 - 2018
Sakshi Tomar, Ibraheem Ali, Melanie Ott
Tổng số: 617   
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