Cancer and Metastasis Reviews
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Therapeutic importance and diagnostic function of circRNAs in urological cancers: from metastasis to drug resistance
Cancer and Metastasis Reviews -
Radiation cytogenetics: From chromosomes to single nucleotides and from metaphase cells to tissues
Cancer and Metastasis Reviews - Tập 23 - Trang 341-349 - 2004
This paper provides a broad overview of radiation cytogenetics that is divided into four sections. The first section provides a brief history of metaphase-based analyses for detecting and quantifying human exposure to ionizing radiation. The second section describes technologies for detecting cellular responses to radiation exposure other than DNA damage. The third section discusses molecular cyto......
Autophagy, molecular chaperones, and unfolded protein response as promoters of tumor recurrence
Cancer and Metastasis Reviews - Tập 42 Số 1 - Trang 217-254 - 2023
Mutations of key driver genes in colorectal cancer progression and metastasis
Cancer and Metastasis Reviews - Tập 37 - Trang 173-187 - 2018
The association between mutations of key driver genes and colorectal cancer (CRC) metastasis has been investigated by many studies. However, the results of these studies have been contradictory. Here, we perform a comprehensive analysis to screen key driver genes from the TCGA database and validate the roles of these mutations in CRC metastasis. Using bioinformatics analysis, we identified six key......
Colorectal carcinoma in black and white race
Cancer and Metastasis Reviews - Tập 22 - Trang 67-82 - 2003
Worldwide, colorectal carcinoma (CRC) varies by race-ethnicity. The highest incidence occurs in whites of European descent. Rates in blacks of South Africa are much lower, but rise with migration to westernized countries, i.e. African Americans (blacks) in the US. In the US, CRC age-specific incidence rates increased dramatically with biologic aging for black and white men and women. For all ages,......
Molecular staging of head and neck squamous carcinoma
Cancer and Metastasis Reviews - Tập 15 - Trang 3-10 - 1996
The staging system of head and neck cancer is a Tumor-Node-Metastases system that was developed by the American Joint Committee on Cancer. The stage of the head and neck cancer defines the extent of the lesion and is determined by physical examination, radiologic studies, and pathologic examination. Accurate staging of head and neck cancer is critical since it will determine the treatment modaliti......
Growth factors as mediators of malignant tumor progression
Cancer and Metastasis Reviews - Tập 12 - Trang 215-217 - 1993
Enhanced radiation response through directed molecular targeting approaches
Cancer and Metastasis Reviews - Tập 23 - Trang 277-292 - 2004
In both the pre- and post-human genome sequencing eras, there has been an increase in the understanding of the molecular mechanisms influencing cellular sensitivity to DNA damaging agents such as ionizing radiation. Out of this work have arisen many cellular factors that could be specifically targeted, at the molecular level, to alter the functionality of a single protein or pathway involved in th......
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