Radiation cytogenetics: From chromosomes to single nucleotides and from metaphase cells to tissues

Cancer and Metastasis Reviews - Tập 23 - Trang 341-349 - 2004
James D. Tucker1
1Department of Biological Sciences, Wayne State University, Detroit

Tóm tắt

This paper provides a broad overview of radiation cytogenetics that is divided into four sections. The first section provides a brief history of metaphase-based analyses for detecting and quantifying human exposure to ionizing radiation. The second section describes technologies for detecting cellular responses to radiation exposure other than DNA damage. The third section discusses molecular cytological approaches for analyzing some of the long-term effects of radiation exposure in tissues, including tumors. The final section provides a look towards the future and makes recommendations including suggestions for technological innovations that would enhance the field of radiation cytology.

Tài liệu tham khảo

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