Cancer Epidemiology Biomarkers and Prevention

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UV Dose Determines Key Characteristics of Nonmelanoma Skin Cancer
Cancer Epidemiology Biomarkers and Prevention - Tập 13 Số 12 - Trang 2006-2011 - 2004
Juan M. Ramos, Jaime Villa, Abigail Ruiz, Roy A. Armstrong, Jaime Matta
Abstract Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), known as nonmelanoma skin cancer (NMSC), are the most common cancers worldwide. Although many factors are involved in the pathogenesis of NMSC, UV radiation is an important risk factor. A fundamental question in skin cancer research is whether varying doses of total UV radiation influence key characteristics of NMSC. The hypoth... hiện toàn bộ
Lysophospholipids Are Potential Biomarkers of Ovarian Cancer
Cancer Epidemiology Biomarkers and Prevention - Tập 13 Số 7 - Trang 1185-1191 - 2004
Rebecca Sutphen, Yan Xu, George D. Wilbanks, James V. Fiorica, Edward C. Grendys, James P. LaPolla, Hector Arango, Mitchell Hoffman, Martin A Martino, Katie Wakeley, David Ray Griffin, Rafael W. Blanco, Alan Cantor, Yijin Xiao, Jeffrey P. Krischer
Abstract Objective: To determine whether lysophosphatidic acid (LPA) and other lysophospholipids (LPL) are useful markers for diagnosis and/or prognosis of ovarian cancer in a controlled setting. Method: Plasma samples were collected from ovarian cancer patients and healthy control women in Hillsborough and Pinellas counties, Florida, and processed at the University of South Florida H. Lee Moffitt... hiện toàn bộ
Lead Exposure, Polymorphisms in Genes Related to Oxidative Stress, and Risk of Adult Brain Tumors
Cancer Epidemiology Biomarkers and Prevention - Tập 18 Số 6 - Trang 1841-1848 - 2009
Parveen Bhatti, Patricia A. Stewart, Amy Hutchinson, Nathaniel Rothman, Martha S. Linet, Peter D. Inskip, Preetha Rajaraman
Abstract There is some evidence that oxidative stress plays a role in lead-induced toxicity. Mechanisms for dealing with oxidative stress may be of particular relevance in the brain given the high rate of oxygen metabolism. Using a hospital-based case-control study, we investigated the role of oxidative stress in the potential carcinogenicity of lead through examination of effect modification of t... hiện toàn bộ
Coffee, Tea, Caffeine Intake, and Risk of Adult Glioma in Three Prospective Cohort Studies
Cancer Epidemiology Biomarkers and Prevention - Tập 19 Số 1 - Trang 39-47 - 2010
Crystal N. Holick, Scott Smith, Edward L. Giovannucci, Dominique S. Michaud
Abstract Current data suggest that caffeinated beverages may be associated with lower risk of glioma. Caffeine has different effects on the brain, some of which could play a role in brain carcinogenesis, and coffee has been consistently associated with reduced risk of liver cancer, thus suggesting a potential anticarcinogenic effect. A total of 335 incident cases of gliomas (men, 133; women, 202) ... hiện toàn bộ
The Heritability of Mammographically Dense and Nondense Breast Tissue
Cancer Epidemiology Biomarkers and Prevention - Tập 15 Số 4 - Trang 612-617 - 2006
Jennifer Stone, Gillian S. Dite, Anoma Gunasekara, Dallas R. English, Margaret McCredie, Graham G. Giles, Jennifer Cawson, Robert A. Hegele, Anna M. Chiarelli, Martin J. Yaffe, Norman F. Boyd, John L. Hopper
Abstract Background: Percent mammographic density (PMD) is a risk factor for breast cancer. Our previous twin study showed that the heritability of PMD was 63%. This study determined the heritabilities of the components of PMD, the areas of dense and nondense tissue in the mammogram. Methods: We combined two twin studies comprising 571 monozygous and 380 dizygous twin pairs recruited from Australi... hiện toàn bộ
A Longitudinal Investigation of Mammographic Density: The Multiethnic Cohort
Cancer Epidemiology Biomarkers and Prevention - Tập 15 Số 4 - Trang 732-739 - 2006
Gertraud Maskarinec, Ian Pagano, Galina Lurie, Laurence N. Kolonel
AbstractMammographic densities are hypothesized to reflect the cumulative exposure to risk factors that influence breast cancer incidence. This report analyzed percent densities over time and explored predictors of density change in relation to age. The study population consisted of 607 breast cancer cases and 667 frequency matched controls with 1,956 and 1,619 mammographic readings, respectively.... hiện toàn bộ
Body Size, Mammographic Density, and Breast Cancer Risk
Cancer Epidemiology Biomarkers and Prevention - Tập 15 Số 11 - Trang 2086-2092 - 2006
Norman F. Boyd, Lisa Martin, Limei Sun, Helen Guo, Anna M. Chiarelli, Greg Hislop, Martin J. Yaffe, Salomon Minkin
AbstractBackground: Greater weight and body mass index (BMI) are negatively correlated with mammographic density, a strong risk factor for breast cancer, and are associated with an increased risk of breast cancer in postmenopausal women, but with a reduced risk in premenopausal women. We have examined the associations of body size and mammographic density on breast cancer risk.Method: We examined ... hiện toàn bộ
The Role of Established Breast Cancer Susceptibility Loci in Mammographic Density in Young Women
Cancer Epidemiology Biomarkers and Prevention - Tập 17 Số 1 - Trang 258-260 - 2008
Eunjung Lee, Christopher A. Haiman, Huiyan Ma, David J. Van Den Berg, Leslie Bernstein, Giske Ursin
Cardiovascular Risk Factors in Adult Survivors of Pediatric Cancer—A Report from the Childhood Cancer Survivor Study
Cancer Epidemiology Biomarkers and Prevention - Tập 19 Số 1 - Trang 170-181 - 2010
Lillian R. Meacham, Eric J. Chow, Kirsten K. Ness, Kala Y. Kamdar, Yan Chen, Yutaka Yasui, Kevin C. Oeffinger, Charles A. Sklar, Leslie L. Robison, Ann C. Mertens
Abstract Background: Childhood cancer survivors are at higher risk of morbidity and mortality from cardiovascular disease compared with the general population. Methods: Eight thousand five hundred ninety-nine survivors (52% male) and 2,936 siblings (46% male) from the Childhood Cancer Survivor Study, a retrospectively ascertained, prospectively followed study of persons who survived 5 years after ... hiện toàn bộ
The Microbiome in Lung Cancer Tissue and Recurrence-Free Survival
Cancer Epidemiology Biomarkers and Prevention - Tập 28 Số 4 - Trang 731-740 - 2019
Brandilyn A. Peters, Richard B. Hayes, Chandra Goparaju, Christopher M. Reid, Harvey I. Pass, Jiyoung Ahn
Abstract Background: Human microbiota have many functions that could contribute to cancer initiation and/or progression at local sites, yet the relation of the lung microbiota to lung cancer prognosis has not been studied. Methods: In a pilot study, 16S rRNA gene sequencing was performed on paired lung tumor and remote normal samples from the same lobe/segment in 19 patients with non–small cell lu... hiện toàn bộ
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