Coffee, Tea, Caffeine Intake, and Risk of Adult Glioma in Three Prospective Cohort Studies

Cancer Epidemiology Biomarkers and Prevention - Tập 19 Số 1 - Trang 39-47 - 2010
Crystal N. Holick1,2,3, Scott Smith1,2,3, Edward L. Giovannucci1, Dominique S. Michaud1,2
1Authors' Affiliations: Departments of 1Epidemiology and 2Nutrition, Harvard School of Public Health; and 3Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; and 4Department of Epidemiology and Public Health, Faculty of Medicine, Imperial College London, London, United Kingdom
2Authors' Affiliations: Departments of Epidemiology and Nutrition, Harvard School of Public Health
3Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts

Tóm tắt

Abstract Current data suggest that caffeinated beverages may be associated with lower risk of glioma. Caffeine has different effects on the brain, some of which could play a role in brain carcinogenesis, and coffee has been consistently associated with reduced risk of liver cancer, thus suggesting a potential anticarcinogenic effect. A total of 335 incident cases of gliomas (men, 133; women, 202) were available from three independent cohort studies. Dietary intake was assessed by food frequency questionnaires obtained at baseline and during follow-up. Cox proportional hazard models were used to estimate incidence rate ratios (RR) and 95% confidence intervals (CI) between consumption of coffee, tea, carbonated beverages, caffeine, and glioma risk adjusting for age and total caloric intake. Estimates from each cohort were pooled using a random-effects model. Consumption of five or more cups of coffee and tea daily compared with no consumption was associated with a decrease risk of glioma (RR, 0.60; 95% CI, 0.41-0.87; Ptrend = 0.04). Inverse, although weaker, associations were also observed between coffee, caffeinated coffee, tea, and carbonated beverages and glioma risk. No association was observed between decaffeinated coffee and glioma risk. Among men, a statistically significant inverse association was observed between caffeine consumption and risk of glioma (RR, 0.46; 95% CI, 0.26-0.81; Ptrend = 0.03); the association was weaker among women. Our findings suggest that consumption of caffeinated beverages, including coffee and tea, may reduce the risk of adult glioma, but further research is warranted to confirm these findings in other populations. Cancer Epidemiol Biomakers Prev; 19(1);39–47

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Tài liệu tham khảo

Nehlig, 1994, Potential genotoxic, mutagenic and antimutagenic effects of coffee: a review, Mutat Res, 317, 145, 10.1016/0165-1110(94)90022-1

Nehlig, 1992, Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects, Brain Res Brain Res Rev, 17, 139, 10.1016/0165-0173(92)90012-B

Lunt, 2004, Comparison of caffeine-induced changes in cerebral blood flow and middle cerebral artery blood velocity shows that caffeine reduces middle cerebral artery diameter, Physiol Meas, 25, 467, 10.1088/0967-3334/25/2/006

Croft, 1998, The chemistry and biological effects of flavonoids and phenolic acids, Ann N Y Acad Sci, 854, 435, 10.1111/j.1749-6632.1998.tb09922.x

Scalbert, 2000, Dietary intake and bioavailability of polyphenols, J Nutr, 130, 2073, 10.1093/jn/130.8.2073S

Larsson, 2007, Coffee consumption and risk of liver cancer: a meta-analysis, Gastroenterology, 132, 1740, 10.1053/j.gastro.2007.03.044

Efird, 2004, The risk for malignant primary adult-onset glioma in a large, multiethnic, managed-care cohort: cigarette smoking and other lifestyle behaviors, J Neurooncol, 68, 57, 10.1023/B:NEON.0000024746.87666.ed

Hochberg, 1990, Nonoccupational risk indicators of glioblastoma in adults, J Neurooncol, 8, 55, 10.1007/BF00182087

Burch, 1987, An exploratory case-control study of brain tumors in adults, J Natl Cancer Inst, 78, 601

Lee, 1997, Dietary and tobacco risk factors for adult onset glioma in the San Francisco Bay Area (California, USA), Cancer Causes Control, 8, 13, 10.1023/A:1018470802969

Blowers, 1997, Dietary and other lifestyle factors of women with brain gliomas in Los Angeles County (California, USA), Cancer Causes Control, 8, 5, 10.1023/A:1018437031987

Giles, 1994, Dietary factors and the risk of glioma in adults: results of a case-control study in Melbourne, Australia, Int J Cancer, 59, 357, 10.1002/ijc.2910590311

Belanger, 1978, The Nurses' Health Study, Am J Nurs, 78, 1039

Colditz, 1990, The Nurses' Health Study: findings during 10 years of follow-up of a cohort of U.S. women, Curr Prob in Obstet Gynecol Fertil, 13, 130

Willett, 1985, Reproducibility and validity of a semiquantitative food frequency questionnaire, Am J Epidemiol, 122, 51, 10.1093/oxfordjournals.aje.a114086

Rimm, 1992, Reproducibility and validity of a expanded self-administered semiquantitative food frequency questionnaire among male health professionals, Am J Epidemiol, 135, 1114, 10.1093/oxfordjournals.aje.a116211

Feskanich, 1993, Reproducibility and validity of food intake measurements from a semiquantitative food frequency questionnaire, J Am Diet Assoc, 93, 790, 10.1016/0002-8223(93)91754-E

Willett, 1988, The use of a self-administered questionnaire to assess diet four years in the past, Am J Epidemiol, 127, 188, 10.1093/oxfordjournals.aje.a114780

Salvini, 1989, Food-based validation of a dietary questionnaire: the effects of week-to-week variation in food consumption, Int J Epidemiol, 18, 858, 10.1093/ije/18.4.858

Stampfer, 1984, Test of the National Death Index, Am J Epidemiol, 119, 837, 10.1093/oxfordjournals.aje.a113804

Chapman, 1968, Asymptotic power of χ2 tests for linear trends in proportions, Biometrics, 24, 315, 10.2307/2528037

Willett, 1998, Nutritional Epidemiology, 2nd ed., 10.1093/acprof:oso/9780195122978.001.0001

Hu, 1999, Dietary fat and coronary heart disease: a comparison of approaches for adjusting total energy intake and modeling repeated dietary measurements, Am J Epidemiol, 149, 531, 10.1093/oxfordjournals.aje.a009849

Durrleman, 1989, Flexible regression models with cubic splines, Stat Med, 8, 551, 10.1002/sim.4780080504

DerSimonian, 1986, Meta-analysis in clinical trials, Control Clin Trials, 7, 177, 10.1016/0197-2456(86)90046-2

CBTRUS, 2005, Statistical Report: Primary Brain Tumors in the United States, 1998-2002: Central Brain Tumor Registry of the United States

Ascherio, 2001, Prospective study of caffeine consumption and risk of Parkinson's disease in men and women, Ann Neurol, 50, 56, 10.1002/ana.1052

Ascherio, 2003, Caffeine, postmenopausal estrogen, and risk of Parkinson's disease, Neurology, 60, 790, 10.1212/01.WNL.0000046523.05125.87

Ascherio, 2004, Coffee consumption, gender, and Parkinson's disease mortality in the cancer prevention study II cohort: the modifying effects of estrogen, Am J Epidemiol, 160, 977, 10.1093/aje/kwh312

Frei, 2003, Antioxidant activity of tea polyphenols in vivo: evidence from animal studies, J Nutr, 133, 3275, 10.1093/jn/133.10.3275S

Yang, 2002, Inhibition of carcinogenesis by tea, Annu Rev Pharmacol Toxicol, 42, 25, 10.1146/annurev.pharmtox.42.082101.154309

Ju, 2007, Inhibition of carcinogenesis by tea constituents, Semin Cancer Biol, 17, 395, 10.1016/j.semcancer.2007.06.013

Barone, 1996, Caffeine consumption, Food Chem Toxicol, 34, 119, 10.1016/0278-6915(95)00093-3

Bode, 2007, The enigmatic effects of caffeine in cell cycle and cancer, Cancer Lett, 247, 26, 10.1016/j.canlet.2006.03.032

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Cancer Epidemiology Biomarkers and Prevention

Tập 19 Số 1

39-47

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