CNS Neuroscience and Therapeutics
SCOPUS (2008-2023)SCIE-ISI
1755-5949
1755-5930
Anh Quốc
Cơ quản chủ quản: WILEY , Wiley-Blackwell Publishing Ltd
Lĩnh vực:
Psychiatry and Mental HealthPharmacology (medical)PharmacologyPhysiology (medical)
Các bài báo tiêu biểu
Mitochondrial Dysfunction and Biogenesis in Neurodegenerative diseases: Pathogenesis and TreatmentSummary Neurodegenerative diseases are a heterogeneous group of disorders that are incurable and characterized by the progressive degeneration of the function and structure of the central nervous system (CNS ) for reasons that are not yet understood. Neurodegeneration is the umbrella term for the progressi... ...
Tập 23 Số 1 - Trang 5-22 - 2017
Inhibition of ferroptosis attenuates tissue damage and improves long‐term outcomes after traumatic brain injury in miceSummary Aims Ferroptosis, a new form of iron‐dependent programmed cell death, has been shown to be involved in a range of diseases. However, the role of ferroptosis in traumatic brain injury (TBI ) has yet to be elucidated. We aimed to investigate whether ferroptosis is in...
Tập 25 Số 4 - Trang 465-475 - 2019
Mechanisms of Efficacy of CBT for Cambodian Refugees with PTSD: Improvement in Emotion Regulation and Orthostatic Blood Pressure ResponseBased on the results of a randomized controlled trial, we examined a model of the mechanisms of efficacy of culturally adapted cognitive‐behavior therapy (CBT) for Cambodian refugees with pharmacology‐resistant posttraumatic stress disorder (PTSD) and comordid orthostatic panic attacks (PAs). Twelve patients were in the initial treatment condition, 12 in the delayed treatment condition. Th... ...
Tập 15 Số 3 - Trang 255-263 - 2009
Melatonin protects against ischemic stroke by modulating microglia/macrophage polarization toward anti‐inflammatory phenotype through STAT3 pathwayAbstract Aims Microglia and infiltrated macrophages play important roles in inflammatory processes after ischemic stroke. Modulating microglia/macrophage polarization from pro‐inflammatory phenotype to anti‐inflammatory state has been suggested as a potential therapeutic approach in the treatment of ischemic stroke. Melatonin has be...
Tập 25 Số 12 - Trang 1353-1362 - 2019
Treating Major Depression by Creating Positive Expectations for the Future: A Pilot Study for the Effectiveness of Future‐Directed Therapy (FDT) on Symptom Severity and Quality of LifeSUMMARY Introduction: This nonrandomized pilot study assesses the efficacy of a new future‐oriented form of therapy, known as future‐directed therapy (FDT), as a treatment for patients with Major Depressive Disorder (MDD) in a naturalistic hospital‐based outpatient psychiatry clinic. The study measured symptom severity of depression and anxiety...
Tập 18 Số 2 - Trang 102-109 - 2012
Exercise, brain plasticity, and depressionAbstract Depression is a common mental disorder characterized by high incidence, high disability, and high fatality, causing great burden to the society, families, and individuals. The changes in brain plasticity may be a main reason for depression. Recent studies have shown that exercise plays a positive role in depression, but systematic and comprehensive studies ... ...
Tập 26 Số 9 - Trang 885-895 - 2020
Quercetin Improves Behavioral Deficiencies, Restores Astrocytes and Microglia, and Reduces Serotonin Metabolism in 3‐Nitropropionic Acid‐Induced Rat Model of Huntington's DiseaseSummary Aim Huntington's disease (HD ) is an autosomal dominant disorder, for which clinically available drugs offer only symptomatic relief. These prescription drugs are not free of side effects, and the patients usually suffer from anxiety and depression. We investigated...
Tập 20 Số 1 - Trang 10-19 - 2014
Pharmacotherapy for Alcohol Dependence: The 2015 Recommendations of the French Alcohol Society, Issued in Partnership with the European Federation of Addiction SocietiesSummary Background The latest French good practice recommendations (GPR s) for the screening, prevention, and treatment of alcohol misuse were recently published in partnership with the European Federation of Addiction Societies (EUF...
Tập 22 Số 1 - Trang 25-37 - 2016
Antiepileptics Topiramate and Levetiracetam Alleviate Behavioral Deficits and Reduce Neuropathology in APP swe/PS 1dE9 Transgenic MiceSummary Background The close relationship between epileptic seizure and Alzheimer's disease (AD ) has been demonstrated in the past decade. Valproic acid, a traditional first‐line antiepileptic drug, exerted protective effects in transgenic models of ...
Tập 19 Số 11 - Trang 871-881 - 2013
Oligodendrocyte Pathophysiology and Treatment Strategies in Cerebral IschemiaSummary Oligodendrocytes (OL s), the myelin‐forming cells of the central nervous system, form a functional unit with axons and play a crucial role in axonal integrity. An episode of hypoxia–ischemia causes rapid and severe damage to these particularly vulnerable cells via multiple pathways such as overacti... ...
Tập 20 Số 7 - Trang 603-612 - 2014