CNS Neuroscience and Therapeutics

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
L‐3‐n‐butylphthalide Promotes Neurogenesis and Neuroplasticity in Cerebral Ischemic Rats
CNS Neuroscience and Therapeutics - Tập 21 Số 9 - Trang 733-741 - 2015
Li‐Chao Yang, Jiang Li, Shaofeng Xu, Jie Cai, Hui Lei, Dongmei Liu, Man Zhang, Xianfang Rong, Dandan Cui, Ling Wang, Ying Peng, Xiao‐Liang Wang
SummaryAimsThis study investigated whether anticerebral ischemia new drug, l‐3‐n‐butylphthalide (l‐NBP), improved behavioral recovery and enhanced hippocampal neurogenesis after cerebral ischemia in rats.Methods and Results... hiện toàn bộ
Mitochondrial Dysfunction and Biogenesis in Neurodegenerative diseases: Pathogenesis and Treatment
CNS Neuroscience and Therapeutics - Tập 23 Số 1 - Trang 5-22 - 2017
Mojtaba Golpich, Elham Amini, Zahurin Mohamed, Azman Ali Raymond, Norlinah Mohamed Ibrahim, Abolhassan Ahmadiani
SummaryNeurodegenerative diseases are a heterogeneous group of disorders that are incurable and characterized by the progressive degeneration of the function and structure of the central nervous system (CNS) for reasons that are not yet understood. Neurodegeneration is the umbrella term for the progressi...... hiện toàn bộ
Neuroprotective Effects of Icariin on Brain Metabolism, Mitochondrial Functions, and Cognition in Triple‐Transgenic Alzheimer's Disease Mice
CNS Neuroscience and Therapeutics - Tập 22 Số 1 - Trang 63-73 - 2016
Yijing Chen, Hai‐Yang Zheng, Xiuxian Huang, Shuangxue Han, Dongsheng Zhang, Jiazuan Ni, Xiaoyang He
SummaryAimsThis study investigated the neuroprotective properties of icariin (an effective component of traditional Chinese herbal medicine Epimedium) on neuronal function and brain energy metabolism maintenance in a triple‐transgenic mouse model of Alzheimer's disease (3 × Tg‐AD).... hiện toàn bộ
miR‐101 Acts as a Tumor Suppressor by Targeting Kruppel‐like Factor 6 in Glioblastoma Stem Cells
CNS Neuroscience and Therapeutics - Tập 21 Số 1 - Trang 40-51 - 2015
Yilong Yao, Jun Ma, Ping Wang, Yixue Xue, Zhen Li, Li‐Ni Zhao, Zhiqing Li, Tian‐Da Feng, Yunhui Liu
SummaryBackground and aimsGreat interest persists in useful therapeutic targets in glioblastoma (GBM). Deregulation of microRNAs (miRNAs) expression has been associated with cancer formation through alteratio...... hiện toàn bộ
Treating Major Depression by Creating Positive Expectations for the Future: A Pilot Study for the Effectiveness of Future‐Directed Therapy (FDT) on Symptom Severity and Quality of Life
CNS Neuroscience and Therapeutics - Tập 18 Số 2 - Trang 102-109 - 2012
Jennice Vilhauer, Sabrina Young, Chanel Kealoha, Josefine Borrmann, Waguih William IsHak, Mark Hyman Rapaport, Narineh Hartoonian, Jim Mirocha
SUMMARYIntroduction:This nonrandomized pilot study assesses the efficacy of a new future‐oriented form of therapy, known as future‐directed therapy (FDT), as a treatment for patients with Major Depressive Disorder (MDD) in a naturalistic hospital‐based outpatient psychiatry clinic. The study measured symptom severity of depression and anxiety...... hiện toàn bộ
Inhibition of ferroptosis attenuates tissue damage and improves long‐term outcomes after traumatic brain injury in mice
CNS Neuroscience and Therapeutics - Tập 25 Số 4 - Trang 465-475 - 2019
Baoshu Xie, Yi‐Qin Wang, Yong Lin, Qing Mao, Junfeng Feng, Guoyi Gao, Jiyao Jiang
SummaryAimsFerroptosis, a new form of iron‐dependent programmed cell death, has been shown to be involved in a range of diseases. However, the role of ferroptosis in traumatic brain injury (TBI) has yet to be elucidated. We aimed to investigate whether ferroptosis is in...... hiện toàn bộ
Expression Profile of Long Noncoding RNAs in Peripheral Blood Mononuclear Cells from Multiple Sclerosis Patients
CNS Neuroscience and Therapeutics - Tập 22 Số 4 - Trang 298-305 - 2016
Fang Zhang, Chao Gao, Xiaofeng Ma, Xiaolin Peng, Rongxin Zhang, Dexin Kong, Alain R. Simard, Junwei Hao
SummaryAimsLong noncoding RNAs (lncRNAs) play a key role in regulating immunological functions. Their impact on the chronic inflammatory disease multiple sclerosis (MS<...... hiện toàn bộ
Quercetin Improves Behavioral Deficiencies, Restores Astrocytes and Microglia, and Reduces Serotonin Metabolism in 3‐Nitropropionic Acid‐Induced Rat Model of Huntington's Disease
CNS Neuroscience and Therapeutics - Tập 20 Số 1 - Trang 10-19 - 2014
Joy Chakraborty, R. P. Singh, Debashis Dutta, Amit K. Naskar, Usha Rajamma, Kochupurackal P. Mohanakumar
SummaryAimHuntington's disease (HD) is an autosomal dominant disorder, for which clinically available drugs offer only symptomatic relief. These prescription drugs are not free of side effects, and the patients usually suffer from anxiety and depression. We investigated...... hiện toàn bộ
Oligodendrocyte Pathophysiology and Treatment Strategies in Cerebral Ischemia
CNS Neuroscience and Therapeutics - Tập 20 Số 7 - Trang 603-612 - 2014
Gabriella Mifsud, Christian Zammit, Richard Muscat, Giuseppe Di Giovanni, Mario Valentino
SummaryOligodendrocytes (OLs), the myelin‐forming cells of the central nervous system, form a functional unit with axons and play a crucial role in axonal integrity. An episode of hypoxia–ischemia causes rapid and severe damage to these particularly vulnerable cells via multiple pathways such as overacti...... hiện toàn bộ
Melatonin protects against ischemic stroke by modulating microglia/macrophage polarization toward anti‐inflammatory phenotype through STAT3 pathway
CNS Neuroscience and Therapeutics - Tập 25 Số 12 - Trang 1353-1362 - 2019
Zongjian Liu, Yuanyuan Ran, Shuyan Qie, Weijun Gong, Fuhai Gao, Zitong Ding, Jianing Xi
AbstractAimsMicroglia and infiltrated macrophages play important roles in inflammatory processes after ischemic stroke. Modulating microglia/macrophage polarization from pro‐inflammatory phenotype to anti‐inflammatory state has been suggested as a potential therapeutic approach in the treatment of ischemic stroke. Melatonin has be...... hiện toàn bộ
Tổng số: 23   
  • 1
  • 2
  • 3