Brain and Behavior
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Brain and Behavior - Tập 7 Số 3 - 2017
AbstractIntroductionSome glial–neuronal tumors (GNT) (pleomorphic
xantho‐astrocytoma [PXA], ganglioglioma [GG]) display BRAF‐V600E mutation, which
represents a diagnostic clue to these entities. Targeted therapies against
BRAF‐V600 protein have shown promising results in GNT. The aim of this study was
to assess the utility of BRAF‐V600E immunohistochemistry (IHC, clone VE1) in
daily practice in a ...
Non‐motor phenotypic subgroups in adult‐onset idiopathic, isolated, focal cervical dystonia
Brain and Behavior - Tập 11 Số 8 - 2021
AbstractBackground: Non‐motor symptoms are well established phenotypic
components of adult‐onset idiopathic, isolated, focal cervical dystonia
(AOIFCD). However, improved understanding of their clinical heterogeneity is
needed to better target therapeutic intervention. Here, we examine non‐motor
phenotypic features to identify possible AOIFCD subgroups.Methods: Participants
diagnosed with AOIFCD w...
Nonmotor symptoms in primary adult‐onset cervical dystonia and blepharospasm
Brain and Behavior - Tập 7 Số 2 - 2017
AbstractBackgroundThe nature and frequency of nonmotor symptoms in primary
adult‐onset cervical dystonia (CD) and blepharospasm (BSP) patients in Chinese
populations remain unknown.MethodsHamilton's Depression Scale (HAMD), Hamilton's
Anxiety Scale (HAMA), Addenbrooke's Cognitive Examination Revised (ACE‐R),
Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale were used to
evaluate NMS in 1...
Underestimated associated features in CMT neuropathies: clinical indicators for the causative gene?
Brain and Behavior - Tập 6 Số 4 - 2016
AbstractIntroductionCharcot–Marie–Tooth neuropathy (CMT) is a genetically
heterogeneous group of peripheral neuropathies. In addition to the classical
clinical phenotype, additional features can occur.MethodsWe studied a wide range
of additional features in a cohort of 49 genetically confirmed CMT patients and
performed a systematic literature revision.ResultsPatients harbored a PMP22 gene
alterat...
Risk of intracranial bleeding in patients with primary brain cancer receiving therapeutic anticoagulation for venous thromboembolism: A meta‐analysis
Brain and Behavior - Tập 10 Số 6 - 2020
AbstractIntroductionVenous thromboembolism (VTE) is common in glioma patients.
Also, spontaneous intracerebral hemorrhage (ICH) is frequently observed in
subjects with primary brain tumors. Thus, the management of anticoagulant
therapy for VTE is challenging and controversial in these patients. We performed
a meta‐analysis to clarify the risk of ICH in glioma patients treated with
anticoagulant th...
Low vitamin D levels and the long‐term functional outcome of stroke up to 5 years
Brain and Behavior - Tập 11 Số 10 - 2021
AbstractBackground and purposePrevious studies have established that vitamin D
was associated with stroke. The purpose of this study was to investigate the
relationship between vitamin D and 5‐year outcome of patients with stroke
including acute ischemic stroke (AIS) and intracranial hemorrhage (ICH)
stroke.MethodsSerum 25‐hydroxyvitamin D levels were prospectively analyzed in
patients admitted to...
Relationship between serum vitamin D levels and inflammatory markers in acute stroke patients
Brain and Behavior - Tập 8 Số 2 - 2018
AbstractIntroductionLow serum vitamin D levels are associated with the
development of poststroke depression (PSD). Inflammatory markers play an
important role in pathophysiology of PSD. The relationship between vitamin D
levels and inflammatory markers has been discussed in nonstroke individuals. The
purposes of this study were to explore the relationship between vitamin D levels
and inflammatory ...
Cortical asymmetry in Parkinson's disease: early susceptibility of the left hemisphere
Brain and Behavior - Tập 6 Số 12 - 2016
AbstractBackground and PurposeClinically, Parkinson's disease (PD) presents with
asymmetric motor symptoms. The left nigrostriatal system appears more
susceptible to early degeneration than the right, and a left‐lateralized pattern
of early neuropathological changes is also described in several
neurodegenerative conditions, including Alzheimer's disease, frontotemporal
dementia, and Huntington's d...
The novel GLP‐1/GIP analogue DA5‐CH reduces tau phosphorylation and normalizes theta rhythm in the icv. STZ rat model of AD
Brain and Behavior - Tập 10 Số 3 - 2020
AbstractIntroductionAlzheimer's disease (AD) is the most common progressive
neurodegenerative disease for which there is no cure. Recent studies have shown
a close link between type 2 diabetes and AD, which suggested that drugs for type
2 diabetes may be effective for AD. GLP‐1 and GIP are incretin hormones that can
ameliorate diabetes.MethodsIn the present study, we tested the novel dual
GLP‐1/GI...
The Danish Multiple Sclerosis Registry
Brain and Behavior - Tập 11 Số 1 - 2021
AbstractObjectivesThe Danish Multiple Sclerosis Registry is the oldest operative
and nationwide MS registry. We present The Danish Multiple Sclerosis Registry
with its history, data collection, scientific contribution, and national and
international research collaboration.Materials and MethodsDetailed description
of data collection, completeness, quality optimizing procedures, funding, and
legal, ...
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