Brain Tumor Pathology

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Utility of genome-wide DNA methylation profiling for pediatric-type diffuse gliomas
Brain Tumor Pathology - Tập 40 - Trang 56-65 - 2023
Yoshihiro Otani, Kaishi Satomi, Yasuki Suruga, Joji Ishida, Kentaro Fujii, Koichi Ichimura, Isao Date
Despite the current progress of treatment, pediatric-type diffuse glioma is one of the most lethal primary malignant tumors in the central nervous system (CNS). Since pediatric-type CNS tumors are rare disease entities and highly heterogeneous, the diagnosis is challenging. An accurate diagnosis is essential for the choice of optimal treatment, which leads to precision oncology and improvement of ...... hiện toàn bộ
Recurrence and regrowth of benign meningiomas
Brain Tumor Pathology - Tập 26 - Trang 69-72 - 2009
Satoshi Nakasu, Tadateru Fukami, Jyunya Jito, Kazuhiko Nozaki
The World Health Organization (WHO) grading system for meningioma is helpful for predicting aggressive subtypes. However, even benign meningiomas sometimes show relatively rapid growth and may recur after total removal. We attempted to find histopathological features that would be valuable for predicting recurrence or regrowth of WHO grade I meningiomas. We investigated 135 benign meningiomas, of ...... hiện toàn bộ
Oligodendroglial ganglioglioma
Brain Tumor Pathology - - 2011
Shinji Yamashita, Kiyotaka Yokogami, Takeya Niibo, Go Takeishi, Toshikatsu Ikeda, Shiro Maeda, Hisao Uehara, Tsuyoshi Fukushima, Yoichi Nakazato, Hideo Takeshima
Correlation of diagnostic yield of stereotactic brain biopsy with number of biopsy bits and site of the lesion
Brain Tumor Pathology - Tập 23 - Trang 71-75 - 2006
Deepali Jain, Mehar Chand Sharma, Chitra Sarkar, Prabal Deb, Deepak Gupta, A.K. Mahapatra
Our objective was to examine the reliability of histological diagnosis achieved vis a vis the number of biopsy bits obtained along a single trajectory of the stereotactic needle. A retrospective analysis of stereotactic biopsies performed in a single tertiary care neurosciences center, during a period of 11 years, between 1995 to 2005 was done. The overall diagnostic accuracy achieved on histopath...... hiện toàn bộ
Pathological features of highly invasive glioma stem cells in a mouse xenograft model
Brain Tumor Pathology - Tập 31 - Trang 77-84 - 2013
Hirokazu Sadahiro, Koichi Yoshikawa, Makoto Ideguchi, Koji Kajiwara, Aya Ishii, Eiji Ikeda, Yuji Owada, Yuki Yasumoto, Michiyasu Suzuki
Glioma stem cells (GSCs) may be a source of tumor progression and recurrence after multimodal therapy, because of their high invasive potential. The purpose of this study was to compare the invasive and migratory properties of GSCs and non-GSCs and examine the distribution of these cells in a mouse xenograft model. Three GSC lines, G144, Y02, and Y10, cultured from human glioblastoma, were used in...... hiện toàn bộ
C11orf95–RELA fusion present in a primary supratentorial ependymoma and recurrent sarcoma
Brain Tumor Pathology - Tập 32 - Trang 105-111 - 2014
David Cachia, Khalida Wani, Marta Penas-Prado, Adriana Olar, Ian E. McCutcheon, Robert S. Benjamin, Terri S. Armstrong, Mark R. Gilbert, Kenneth D. Aldape
Ependymomas are rare glial tumors of the central nervous system that arise from the cells lining the ventricles and central canal within the spinal cord. The distribution of these tumors along the neuroaxis varies by age, most commonly involving the spinal cord in adults and the posterior fossa in children. It is becoming evident that ependymomas of infratentorial, supratentorial, and spinal cord ...... hiện toàn bộ
Skull metastasis from papillary thyroid carcinoma accompanied by neurofibromatosis type 1 and pheochromocytoma: report of a case
Brain Tumor Pathology - Tập 23 - Trang 97-100 - 2006
Tetsuo Hashiba, Motohiko Maruno, Yasunori Fujimoto, Tsuyoshi Suzuki, Kouichi Wada, Toshihiko Isaka, Shuichi Izumoto, Toshiki Yoshimine
We report here a 74-year-old woman with a skull metastasis from papillary thyroid carcinoma (PTC). In her medical history, she was diagnosed with neurofibromatosis type 1 (NF1) at age 28 years, and she underwent thyroidectomy for PTC at age 52 years and adrenectomy for pheochromocytoma (PC) at age 58 years. She was admitted to our hospital with an increased mass in the forehead. Head computed tomo...... hiện toàn bộ
Expression of Bcl-2, Bcl-x, and Bax proteins in astrocytomas in relation to patient survival
Brain Tumor Pathology - Tập 18 - Trang 123-129 - 2001
Shigeru Daido, Takashi Tamiya, Yasuhiro Ono, Kinya Terada, Shinichiro Mizumatsu, Takashi Ohmoto
The Bcl-2 family is composed of a group of related proteins that either prevent or promote apoptosis. This study was undertaken to assess the prognostic value of Bcl-2, Bcl-x, and Bax in patients with astrocytomas. Tissue samples from 104 astrocytomas (WHO grade 2, 21 cases; grade 3, 49 cases; grade 4, 34 cases), including 68 primary and 36 recurrent tumors, were examined immunohistochemically for...... hiện toàn bộ
Diencephalic pediatric low-grade glioma harboring the BRAF V600E mutation presenting with various morphologies in sequential biopsy specimens
Brain Tumor Pathology - - 2017
Yukitomo Ishi, Kanako C. Hatanaka, Shigeru Yamaguchi, Hiromi Fujita, Hiroaki Motegi, Hiroyuki Kobayashi, Shunsuke Terasaka, Kiyohiro Houkin
A primary DICER1-sarcoma with KRAS and TP53 mutations in a child with suspected ECCL
Brain Tumor Pathology - - 2022
Kaiyun Yang, Justin Wang, Nisha Kanwar, Anita Villani, Olufemi Ajani, Adam Fleming, Vikas Patil, Yasin Mamatjan, Qingxia Wei, David Malkin, Adam Shlien, Gelareh Zadeh, John Provias
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