1 H, 15 N and 13 C chemical shift assignments of the N-terminal domain of the two isoforms of the human apolipoprotein EBiomolecular NMR Assignments - Tập 16 - Trang 191-196 - 2022
Subhendu Pandit
Apolipoprotein E (ApoE) is one of the major lipid transporters in humans. It is also implicated in pathological conditions like Alzheimer’s and cardiovascular diseases. The N-terminal domain of ApoE binds low-density lipoprotein receptors (LDLR) while the C-terminal domain binds to the lipid. I report the backbone and aliphatic side-chain NMR chemical shifts of the N-terminal domain of two isoform...... hiện toàn bộ
NMR resonance assignments for a ProQ homolog from Legionella pneumophilaBiomolecular NMR Assignments - Tập 12 - Trang 319-322 - 2018
Carina Immer, Carolin Hacker, Jens Wöhnert
Regulation of gene expression on a post-transcriptional level by small non-coding regulatory RNAs (sRNAs) is very common in bacteria. sRNAs base pair with sequences in their target messenger RNAs (mRNAs) and thereby regulate translation initiation or mRNA stability. Specialized RNA-binding proteins (RBPs) facilitate these regulatory sRNA/mRNA interactions by acting as RNA chaperones. A well-known ...... hiện toàn bộ
Backbone and side-chain assignments of an effector membrane localization domain from Vibrio vulnificus MARTX toxinBiomolecular NMR Assignments - Tập 8 - Trang 225-228 - 2013
Michael C. Brothers, Brett Geissler, Grant S. Hisao, Brenda A. Wilson, Karla J. F. Satchell, Chad M. Rienstra
1H, 13C, and 15N chemical shift assignments are presented for the isolated four-helical bundle membrane localization domain from the domain of unknown function 5 (DUF5) effector (MLDVvDUF5) of the MARTX toxin from Vibrio vulnificus in its solution state. We have assigned 97 % of all backbone and side-chain carbon atoms, including 96 % of all backbone residues. Secondary ch...... hiện toàn bộ
NMR assignments of actin depolymerizing factor (ADF) like UNC-60A and cofilin like UNC-60B proteins of Caenorhabditis elegansBiomolecular NMR Assignments - Tập 9 - Trang 261-265 - 2014
Vaibhav Kumar Shukla, Ashish Kabra, Rahul Yadav, Shoichiro Ono, Dinesh Kumar, Ashish Arora
The actin filament dynamics in nematode, Caenorhabditis elegans, is regulated by differential activity of two proteins UNC-60A and UNC-60B. UNC-60A exhibits strong pointed end depolymerization on C. elegans actin (Ce-actin), strong inhibition of polymerization, strong monomer sequestering activity, weak severing activity, and low affinity for F-actin binding, while UNC-60B exhibits strong pointed ...... hiện toàn bộ
NMR resonance assignments of the lantibiotic immunity protein NisI from Lactococcus lactisBiomolecular NMR Assignments - Tập 9 - Trang 293-297 - 2015
Carolin Hacker, Nina Alexandra Christ, Elke Duchardt-Ferner, Sophie Korn, Lucija Berninger, Peter Kötter, Karl-Dieter Entian, Jens Wöhnert
The lantibiotic nisin is a small antimicrobial peptide which acts against a wide range of Gram-positive bacteria. Nisin-producing Lactococcus
lactis strains express four genes for self-protection against their own antimicrobial compound. This immunity system consists of the lipoprotein NisI and the ABC transporter NisFEG. NisI is attached to the outside of the cytoplasmic ...... hiện toàn bộ
Backbone resonance assignment of the response regulator protein PhoBNF20D from Escherichia coliBiomolecular NMR Assignments - Tập 12 - Trang 133-137 - 2018
Xinhui Kou, Xinghong Liu, Yixiang Liu, Conggang Li, Maili Liu, Ling Jiang
PhoB is a response regulator of the PhoR/PhoB two-component signal transduction system that is involved in the regulation of the phosphate (Pho) regulon of Escherichia coli. PhoB has two domains, receiver domain and effector domain. The receiver domain can be phosphorylated by its cognate histidine kinase PhoR and the phosphorylation induces conformational changes of the full length protein of Pho...... hiện toàn bộ
Chemical shift assignments of dsRBD1 and linker region of R2D2, a siRNA binding protein in the Drosophila RNAi pathwayBiomolecular NMR Assignments - Tập 17 - Trang 211-215 - 2023
Ramdas Aute, Mandar V. Deshmukh
In the model organism Drosophila melanogaster, one of the Dicer homologs, Dcr-2, initiates the RNA interference pathway by cleaving long double-stranded RNA into small interfering RNA (siRNA). The Dcr-2:R2D2 heterodimer subsequently binds to the 21-nucleotide siRNA to form the R2D2:Dcr-2 Initiator (RDI) complex, which is critical for initiating the assembly of the RNA-induced silencing complex con...... hiện toàn bộ