Biomechanics and Modeling in Mechanobiology

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Functional in situ assessment of human articular cartilage using MRI: a whole-knee joint loading device
Biomechanics and Modeling in Mechanobiology - Tập 16 - Trang 1971-1986 - 2017
Sven Nebelung, Manuel Post, Stefan Raith, Horst Fischer, Matthias Knobe, Benedikt Braun, Andreas Prescher, Markus Tingart, Johannes Thüring, Philipp Bruners, Holger Jahr, Christiane Kuhl, Daniel Truhn
The response to loading of human articular cartilage as assessed by magnetic resonance imaging (MRI) remains to be defined in relation to histology and biomechanics. Therefore, an MRI-compatible whole-knee joint loading device for the functional in situ assessment of cartilage was developed and validated in this study. A formalin-fixed human knee was scanned by computed tomography in its native co... hiện toàn bộ
Các mối quan hệ hình thái – đàn hồi sử dụng thông tin kết cấu giảm dần của xương xốp người từ ba vị trí giải phẫu chính Dịch bởi AI
Biomechanics and Modeling in Mechanobiology - Tập 12 - Trang 793-800 - 2012
Thomas Gross, Dieter H. Pahr, Philippe K. Zysset
Với sự cải thiện của công nghệ quét CT lâm sàng, độ chính xác của các mô hình phần tử hữu hạn (FE) dựa trên CT của bộ xương người có thể được cải thiện thông qua việc mô tả tốt hơn các tính chất cơ học của xương theo mức độ hiện diện. Mô hình phần tử vi mô (μFE) có thể được sử dụng để nghiên cứu hành vi đàn hồi hiện có của xương xốp người. Trong nghiên cứu này, các mẫu từ xương đùi, xương quay và ... hiện toàn bộ
Non-invasive, energy-based assessment of patient-specific material properties of arterial tissue
Biomechanics and Modeling in Mechanobiology - Tập 14 - Trang 1045-1056 - 2015
M. Smoljkić, J. Vander Sloten, P. Segers, N. Famaey
The mechanical properties of human biological tissue vary greatly. The determination of arterial material properties should be based on experimental data, i.e. diameter, length, intramural pressure, axial force and stress-free geometry. Currently, clinical data provide only non-invasively measured pressure-diameter data for superficial arteries (e.g. common carotid and femoral artery). The lack of... hiện toàn bộ
The collagen fibril architecture in the lamina cribrosa and peripapillary sclera predicted by a computational remodeling approach
Biomechanics and Modeling in Mechanobiology - - 2011
Rafael Grytz, Günther Meschke, Jost B. Jonas
Relationship between Apical Membrane Elasticity and Stress Fiber Organization in Fibroblasts Analyzed by Fluorescence and Atomic Force Microscopy
Biomechanics and Modeling in Mechanobiology - Tập 5 - Trang 263-272 - 2006
S. Kidoaki, T. Matsuda, K. Yoshikawa
To investigate the relationship between cellular microelasticity and the structural features of cytoskeletons (CSKs), a microindentation test for apical cell membranes and observation of the spatio-distribution of actin CSKs of fibroblasts were performed by fluorescence and atomic force microscopy (FM/AFM). The indentation depths of apical cell membranes were measured from AFM force–indentation (f... hiện toàn bộ
Evaluation of growth-induced, mechanical stress in solid tumors and spatial association with extracellular matrix content
Biomechanics and Modeling in Mechanobiology - Tập 22 Số 5 - Trang 1625-1643 - 2023
Andreas Hadjigeorgiou, Triantafyllos Stylianopoulos
A sclerostin-based theory for strain-induced bone formation
Biomechanics and Modeling in Mechanobiology - Tập 10 - Trang 663-670 - 2010
René F. M. van Oers, Bert van Rietbergen, Keita Ito, Peter A. J. Hilbers, Rik Huiskes
Bone formation responds to mechanical loading, which is believed to be mediated by osteocytes. Previous theories assumed that loading stimulates osteocytes to secrete signals that stimulate bone formation. In computer simulations this ‘stimulatory’ theory successfully produced load-aligned trabecular structures. In recent years, however, it was discovered that osteocytes inhibit bone formation via... hiện toàn bộ
Mechanical role of intraluminal thrombus in aneurysm growth: A computational study
Biomechanics and Modeling in Mechanobiology - Tập 20 - Trang 1819-1832 - 2021
Nino Horvat, Lana Virag, Igor Karšaj
Models that seek to improve our current understanding of biochemical processes and predict disease progression have been increasingly in use over the last decades. Recently, we proposed a finite element implementation of arterial wall growth and remodeling with application to abdominal aortic aneurysms (AAAs). The study focused on changes within the aortic wall and did not include the complex role... hiện toàn bộ
Growth mixture model of distraction osteogenesis: effect of pre-traction stresses
Biomechanics and Modeling in Mechanobiology - Tập 9 - Trang 103-115 - 2009
Esther Reina-Romo, M. J. Gómez-Benito, J. M. García-Aznar, J. Domínguez, M. Doblaré
In tensional studies of bone fragments during limb lengthening, it is usually assumed that the stress level in the gap tissue before each distraction step (pre-traction stress) is rather modest. However, during the process of distraction osteogenesis, a large interfragmentary gap is generated and these pre-traction stresses may be important. To date, to the authors’ knowledge, no computational stu... hiện toàn bộ
Evaluating the interaction of a tracheobronchial stent in an ovine in-vivo model
Biomechanics and Modeling in Mechanobiology - Tập 17 - Trang 499-516 - 2017
Donnacha J. McGrath, Anja Lena Thiebes, Christian G. Cornelissen, Barry O’Brien, Stefan Jockenhoevel, Mark Bruzzi, Peter E. McHugh
Tracheobronchial stents are used to restore patency to stenosed airways. However, these devices are associated with many complications such as stent migration, granulation tissue formation, mucous plugging and stent strut fracture. Of these, granulation tissue formation is the complication that most frequently requires costly secondary interventions. In this study a biomechanical lung modelling fr... hiện toàn bộ
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