Biomechanics and Modeling in Mechanobiology
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Experimental determination of folding factor of benign breast cancer cell (MCF10A) and its effect on contact models and 3D manipulation of biological particles
Biomechanics and Modeling in Mechanobiology - Tập 17 - Trang 745-761 - 2017
Plasma membrane of most cells is not smooth. The surfaces of both small and large micropermeable cells are folded and corrugated which makes mammalian cells to have a larger membrane surface than the supposed ideal mode, that is, the smooth sphere of the same volume. Since cancer is an anthropic disease, cancer cells tend to have a larger membrane area than normal cells. Therefore, cancer cells ha...... hiện toàn bộ
A phenomenological model for cell and nucleus deformation during cancer metastasis
Biomechanics and Modeling in Mechanobiology - Tập 17 - Trang 1429-1450 - 2018
Cell migration plays an essential role in cancer metastasis. In cancer invasion through confined spaces, cells must undergo extensive deformation, which is a capability related to their metastatic potentials. Here, we simulate the deformation of the cell and nucleus during invasion through a dense, physiological microenvironment by developing a phenomenological computational model. In our work, ce...... hiện toàn bộ
Characterization of the hemodynamic wall shear stresses in human umbilical vessels from normal and intrauterine growth restricted pregnancies
Biomechanics and Modeling in Mechanobiology - Tập 17 Số 4 - Trang 1107-1117 - 2018
On the anisotropy and inhomogeneity of permeability in articular cartilage
Biomechanics and Modeling in Mechanobiology - Tập 7 - Trang 367-378 - 2007
Articular cartilage is known to be anisotropic and inhomogeneous because of its microstructure. In particular, its elastic properties are influenced by the arrangement of the collagen fibres, which are orthogonal to the bone-cartilage interface in the deep zone, randomly oriented in the middle zone, and parallel to the surface in the superficial zone. In past studies, cartilage permeability has be...... hiện toàn bộ
Image-based analysis and simulation of the effect of platelet storage temperature on clot mechanics under uniaxial strain
Biomechanics and Modeling in Mechanobiology - Tập 19 - Trang 173-187 - 2019
Optimal strength and stability of blood clots are keys to hemostasis and in prevention of hemorrhagic or thrombotic complications. Clots are biocomposite materials composed of fibrin network enmeshing platelets and other blood cells. We have previously shown that the storage temperature of platelets significantly impacts clot structure and stiffness. The objective of this work is to delineate the ...... hiện toàn bộ
Study of protein structural deformations under external mechanical perturbations by a coarse-grained simulation method
Biomechanics and Modeling in Mechanobiology - - 2016
A method for real-time mechanical characterisation of microcapsules
Biomechanics and Modeling in Mechanobiology - Tập 22 - Trang 1209-1220 - 2023
Characterising the mechanical properties of flowing microcapsules is important from both fundamental and applied points of view. In the present study, we develop a novel multilayer perceptron (MLP)-based machine learning (ML) approach, for real-time simultaneous predictions of the membrane mechanical law type, shear and area-dilatation moduli of microcapsules, from their camera-recorded steady pro...... hiện toàn bộ
Estimation of forces on anterior cruciate ligament in dynamic activities
Biomechanics and Modeling in Mechanobiology - Tập 20 - Trang 1533-1546 - 2021
In this work, a nonlinear strain rate dependent plugin developed for the OpenSim® platform was used to estimate the instantaneous strain rate (ISR) and the forces on the ACL’s anteromedial (aACL) and posterolateral (pACL) bundles during walking and sudden change of direction of running termed as ‘plant-and-cut’ (PC). The authors obtained the kinematics data for walking via optical motion capture. ...... hiện toàn bộ
Theoretical and numerical study of a bone remodeling model: The effect of osteocyte cells distribution
Biomechanics and Modeling in Mechanobiology - Tập 3 - Trang 6-16 - 2004
It is well argued that osteocytes are mechanosensory cells and are involved in the regulation of bone remodeling. In previous works, the predictions from a simulation model have suggested that both the influencing distance of osteocytes and the magnitude of the mechanical loads determine the thickness of trabeculae whereas the number of osteocytes primarily affects the rate of bone remodeling. The...... hiện toàn bộ
A perturbation solution of the mechanical bidomain model
Biomechanics and Modeling in Mechanobiology - - 2012
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