BioEssays

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
The IRS‐signalling system during insulin and cytokine action
BioEssays - Tập 19 Số 6 - Trang 491-500 - 1997
Lynne Yenush, Morris F. White
AbstractThe discovery of the first intracellular substrate for insulin, IRS‐1, redirected the field of diabetes research and has led to many important advances in our understanding of insulin action. Detailed analysis of IRS‐1 demonstrates structure/function relationships for this modular docking molecule, including mechanisms of substrate recognition and signal pr...... hiện toàn bộ
How did bacterial ancestors reproduce? Lessons from L‐form cells and giant lipid vesicles
BioEssays - Tập 34 Số 12 - Trang 1078-1084 - 2012
Yves Briers, Peter Walde, Markus Schuppler, Martin J. Loessner
AbstractIn possible scenarios on the origin of life, protocells represent the precursors of the first living cells. To study such hypothetical protocells, giant vesicles are being widely used as a simple model. Lipid vesicles can undergo complex morphological changes enabling self‐reproduction such as growth, fission, and extra‐ and intravesicular budding. These pr...... hiện toàn bộ
Long non‐coding RNAs in cancer metabolism
BioEssays - Tập 38 Số 10 - Trang 991-996 - 2016
Zhen‐Dong Xiao, Li Zhuang, Boyi Gan
Altered cellular metabolism is an emerging hallmark of cancer. Accumulating recent evidence links long non‐coding RNAs (lncRNAs), a still poorly understood class of non‐coding RNAs, to cancer metabolism. Here we review the emerging findings on the functions of lncRNAs in cancer metabolism, with particular emphasis on how lncRNAs regulate glucose and glutamine metabo...... hiện toàn bộ
The vertebrate limb: A model system to study the Hox/hom gene network during development and evolution
BioEssays - Tập 14 Số 6 - Trang 375-384 - 1992
Denis Duboule
AbstractThe potential of the vertebrate limb as a model system to study developmental mechanisms is particularly well illustrated by the analysis of the Hox gene network. These genes are probably involved in the establishment of patterns encoding positional information. Their functional organisation during both limb and trunk development ...... hiện toàn bộ
Early life epigenetic programming and transmission of stress‐induced traits in mammals
BioEssays - Tập 36 Số 5 - Trang 491-502 - 2014
Katharina Gapp, Lukas von Ziegler, Ry Y. Tweedie‐Cullen, Isabelle M. Mansuy
The environment can have a long‐lasting influence on an individual's physiology and behavior. While some environmental conditions can be beneficial and result in adaptive responses, others can lead to pathological behaviors. Many studies have demonstrated that changes induced by the environment are expressed not only by the individuals directly exposed, but also by ...... hiện toàn bộ
The Fox and the thyroid: The amphioxus perspective
BioEssays - Tập 24 Số 8 - Trang 696-699 - 2002
Françoise Mazet
AbstractThe evolutionary origins of several vertebrate organs are still controversial. The thyroid is classically thought to derive directly from the endostyle (a pharyngeal organ found in urochordates, cephalochordates and lampreys). Several molecular and biochemical lines of evidence agree with this scenario. However, a recent paper, hiện toàn bộ
Sex determination: insights from the chicken
BioEssays - Tập 26 Số 2 - Trang 120-132 - 2004
Craig A. Smith, Andrew Sinclair
AbstractNot all vertebrates share the familiar system of XX:XY sex determination seen in mammals. In the chicken and other birds, sex is determined by a ZZ:ZW sex chromosome system. Gonadal development in the chicken has provided insights into the molecular genetics of vertebrate sex determination and how it has evolved. Such comparative studies show that vertebrat...... hiện toàn bộ
Scent wars: the chemobiology of competitive signalling in mice
BioEssays - Tập 26 Số 12 - Trang 1288-1298 - 2004
Jane L. Hurst, Robert J. Beynon
AbstractMany mammals use scent marks to advertise territory ownership, but only recently have we started to understand the complexity of these scent signals and the types of information that they convey. Whilst attention has generally focused on volatile odorants as the main information molecules in scents, studies of the house mouse have now defined a role for a f...... hiện toàn bộ
Metabolic Compartmentation
BioEssays - Tập 10 Số 4 - Trang 127-129 - 1989
H. Olin Spivey, Jerry M. Merz
AbstractEvidence for the association of ‘soluble’ enzymes in vivo is extensive and compelling. These associations occur in all compartments of the cell of both prokaryotes and eukaryotes. Several factors present in vivo promote these associations among enzymes whose association in vitro... hiện toàn bộ
Mitogenesis and protein synthesis: A role for ribosomal protein S6 phosphorylation?
BioEssays - Tập 16 Số 11 - Trang 809-815 - 1994
Mary J. Stewart, George Thomas
AbstractIt has been known for 20 years that the ribosomal protein S6 is rapidly phosphorylated when cells are stimulated to grow or divide. Furthermore, numerous studies have documented that there is a strong correlation between increases in S6 phosphorylation and protein synthesis, leading to the idea that S6 phosphorylation is involved in up‐regulating translatio...... hiện toàn bộ
Tổng số: 121   
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 10