Rachel E. White, Anne-Sophie Biérinx, Viola F. Gnocchi, Peter S. Zammit
AbstractBackgroundPostnatal growth in mouse is rapid, with total skeletal muscle mass increasing several-fold in the first few weeks. Muscle growth can be achieved by either an increase in muscle fibre number or an increase in the size of individual myofibres, or a combination of both. Where my...... hiện toàn bộ
Patricia Fauque, Pierre Jouannet, Corinne Lesaffre, Marie‐Anne Ripoche, Luisa Dandolo, Daniel Vaiman, Hélène Jammes
AbstractBackgroundIn the last few years, an increase in imprinting anomalies has been reported in children born from Assisted Reproductive Technology (ART). Various clinical and experimental studies also suggest alterations of embryo development after ART. Therefore, there is a need for studying e...... hiện toàn bộ
Adrienne E. McKee, Emmanuel Minet, Charlene A. Stern, Shervin Riahi, Charles D. Stiles, Pamela A. Silver
AbstractBackgroundIn eukaryotic cells, RNA-binding proteins (RBPs) contribute to gene expression by regulating the form, abundance, and stability of both coding and non-coding RNA. In the vertebrate brain, RBPs account for many distinctive features of RNA processing such as activity-dependent transcript localization and localized ...... hiện toàn bộ
AbstractBackgroundWhole-mount in situ hybridization (WISH) is extensively used to characterize gene expression patterns in developing and adult brain and other tissues. To obtain an idea whether a novel gene might be involved in specification of a distinct brain subdi...... hiện toàn bộ
Andrie Koutsoulidou, Nikolaos P. Mastroyiannopoulos, Denis Furling, James B. Uney, Leonidas A. Phylactou
AbstractBackgroundMicroRNAs (miRNAs) are small RNA molecules that post-transcriptionally regulate gene expression and have been shown to play an important role during development. miR-1, miR-133a, miR-133b and miR-206 are expressed in muscle tissue and induced during muscle cell differentiation...... hiện toàn bộ
Ewart Kuijk, Leonie du Puy, Helena T A van Tol, Henk P. Haagsman, B. Colenbrander, Bernard A.J. Roelen
AbstractBackgroundIn the developing embryo, total RNA abundance fluctuates caused by functional RNA degradation and zygotic genome activation. These variations in the transcriptome in early development complicate the choice of good reference genes for gene expression studies by quantitative rea...... hiện toàn bộ
Maxime Bouchard, Dominique de Caprona, Meinrad Busslinger, Pin-Xian Xu, Bernd Fritzsch
AbstractBackgroundPax2;5;8transcription factors play diverse roles in vertebrate and invertebrate organogenesis, including the development of the inner ear. Past research has suggested various cochlear defects and some vestibular defects inPax2null mice but the details of the c...... hiện toàn bộ
AbstractBackgroundWe previously identified a set of genes called ECATs (ES cell-associated transcripts) that are expressed at high levels in mouse ES cells. Here, we examine the expression and DNA methylation of ECATs in somatic cells and germ cells.ResultsIn all ECATs...... hiện toàn bộ