Antioxidants

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Nrf2 in Cancer, Detoxifying Enzymes and Cell Death Programs
Antioxidants - Tập 10 Số 7 - Trang 1030
Tabitha Jenkins, Jérôme Gouge
Reactive oxygen species (ROS) play an important role in cell proliferation and differentiation. They are also by-products of aerobic living conditions. Their inherent reactivity poses a threat for all cellular components. Cells have, therefore, evolved complex pathways to sense and maintain the redox balance. Among them, Nrf2 (Nuclear factor erythroid 2-related factor 2) plays a crucial role: it i... hiện toàn bộ
Structure, Antioxidant, and Hypoglycemic Activities of Arabinoxylans Extracted by Multiple Methods from Triticale
Antioxidants - Tập 8 Số 12 - Trang 584
Hong Chen, Zhuoyun Chen, Yuanfang Fu, Jiao Liu, Siying Lin, Qing Zhang, Yuntao Liu, Ding‐Tao Wu, Derong Lin, Guoquan Han, Lina Wang, Wen Qin
Different methods of isolating arabinoxylans (AXs) from triticale were performed to investigate the extraction methods’ effects on the physiological functions of the AXs. Structural, antioxidant, and hypoglycemic activities were determined. The molecular weights (MWs) of enzyme- or water-extracted AXs were lower than those of alkali-extracted AXs. Opposite trends were shown by the arabinose–xylose... hiện toàn bộ
The Activity of the Durum Wheat (Triticum durum L.) Catalase 1 (TdCAT1) Is Modulated by Calmodulin
Antioxidants - Tập 11 Số 8 - Trang 1483
Mouna Ghorbel, Kaouthar Feki, Sana Tounsi, Najla Haddaji, Moez Hanin, Faïçal Brini
Plant catalases (CAT) are involved in the cellular scavenging of the reactive oxygen species during developmental processes and in response to abiotic and biotic stresses. However, little is known about the regulation of the CAT activity to ensure efficient antioxidant function. Using bioinformatic analyses, we showed that durum wheat catalase 1 (TdCAT1) harbors highly conserved cation-binding and... hiện toàn bộ
Honey Extracts Exhibit Cytoprotective Properties against UVB-Induced Photodamage in Human Experimental Skin Models
Antioxidants - Tập 9 Số 7 - Trang 566
Athanasios Karapetsas, Georgia-Persephoni Voulgaridou, Dimitra Iliadi, Ilias Tsochantaridis, Mihalis I. Panayiotidis, Spyridon Kynigopoulos, Maria Lambropoulou, Maria-Ioanna Stavropoulou, Konstantina Stathopoulou, Sofia Karabournioti, Nektarios Aligiannis, Κonstantinos Gardikis, Αlex Galanis, Aglaia Pappa
In the present study, we aimed to examine the antioxidant, antiaging and photoprotective properties of Greek honey samples of various botanical and geographical origin. Ethyl-acetate extracts were used and the and the total phenolic/flavonoid content and antioxidant capacity were evaluated. Honey extracts were then studied for their cytoprotective properties against UVB-induced photodamage using h... hiện toàn bộ
Identification and Expression Profiling of Two Saudi Arabia Catalase Genes from Wheat and Barley in Response to Abiotic and Hormonal Stresses
Antioxidants - Tập 11 Số 11 - Trang 2208
Mouna Ghorbel, Malek Besbes Hlila, Najla Haddaji, Nouha Bouali, Faïçal Brini
Catalase is a crucial enzyme in antioxidant defense systems protecting eukaryotes from oxidative stress. These proteins are present in almost all living organisms and play important roles in controlling plant responses to biotic and abiotic stresses by catalyzing the decomposition of H2O2. Despite their importance, little is known about their expression in the majority of monocotyledonous species.... hiện toàn bộ
Flavones’ and Flavonols’ Antiradical Structure–Activity Relationship—A Quantum Chemical Study
Antioxidants - Tập 9 Số 6 - Trang 461
Maciej Spiegel, Tadeusz Andruniów, Zbigniew Sroka
Flavonoids are known for their antiradical capacity, and this ability is strongly structure-dependent. In this research, the activity of flavones and flavonols in a water solvent was studied with the density functional theory methods. These included examination of flavonoids’ molecular and radical structures with natural bonding orbitals analysis, spin density analysis and frontier molecular orbit... hiện toàn bộ
Can Antioxidants Reduce the Toxicity of Bisphenol?
Antioxidants - Tập 11 Số 2 - Trang 413
Wanda Mączka, Małgorzata Grabarczyk, Katarzyna Wińska
BPA is still the subject of extensive research due to its widespread use, despite its significant toxicity resulting not only from its negative impact on the endocrine system but also from disrupting the organism’s oxidative homeostasis. At the molecular level, bisphenol A (BPA) causes an increased production of ROS and hence a change in the redox balance, mitochondrial dysfunction, and modulation... hiện toàn bộ
Melatonin and Related Compounds: Antioxidant and Anti-Inflammatory Actions
Antioxidants - Tập 11 Số 3 - Trang 532
Maria Anna Bantounou, Josip Plascevic, Helen F. Galley
Melatonin, an indoleamine derived from tryptophan and produced in the pineal gland and other tissues [...]
Oxidative Stress and BPA Toxicity: An Antioxidant Approach for Male and Female Reproductive Dysfunction
Antioxidants - Tập 9 Số 5 - Trang 405
Rosaria Meli, Anna Monnolo, Chiara Annunziata, Claudio Pirozzi, Maria Carmela Ferrante
Bisphenol A (BPA) is a non-persistent anthropic and environmentally ubiquitous compound widely employed and detected in many consumer products and food items; thus, human exposure is prolonged. Over the last ten years, many studies have examined the underlying molecular mechanisms of BPA toxicity and revealed links among BPA-induced oxidative stress, male and female reproductive defects, and human... hiện toàn bộ
Inclusion Complexes of Lycopene and β-Cyclodextrin: Preparation, Characterization, Stability and Antioxidant Activity
Antioxidants - Tập 8 Số 8 - Trang 314
Haixiang Wang, Shaofeng Wang, Hua Zhu, Suilou Wang, Jiudong Xing
In this study, the inclusion complexes of lycopene with β-cyclodextrin (β-CD) were prepared by the precipitation method. Then the inclusion complexes were characterized by the scanning electron microscopy (SEM), ultraviolet-visible spectroscopy (UV), microscopic observation, liquid chromatography, differential scanning calorimetry (DSC) and phase-solubility study. Moreover, the stability and antio... hiện toàn bộ
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