Antimicrobial Agents and Chemotherapy

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
Human Volunteers Receiving Escherichia coli Phage T4 Orally: a Safety Test of Phage Therapy
Antimicrobial Agents and Chemotherapy - Tập 49 Số 7 - Trang 2874-2878 - 2005
Anne Bruttin, Harald Brüssow
ABSTRACT Fifteen healthy adult volunteers received in their drinking water a lower Escherichia coli phage T4 dose (10 3 PFU/ml), a higher phage dose (10 5 PFU/ml), and placebo. Fecal coliphage was detect...... hiện toàn bộ
Slow Release of Nitric Oxide from Charged Catheters and Its Effect on Biofilm Formation by Escherichia coli
Antimicrobial Agents and Chemotherapy - Tập 54 Số 1 - Trang 273-279 - 2010
G. Regev-Shoshani, Mary Ko, Christopher Miller, Yossef Av‐Gay
ABSTRACT Catheter-associated urinary tract infection is the most prevalent cause of nosocomial infections. Bacteria associated with biofilm formation play a key role in the morbidity and pathogenesis of these infections. Nitric oxide (NO) is a naturally produced free radical with proven bactericidal effect. In this study, Foley urinary cathet...... hiện toàn bộ
Antibacterial Activity of Ultrashort Cationic Lipo-β-Peptides
Antimicrobial Agents and Chemotherapy - Tập 53 Số 5 - Trang 2215-2217 - 2009
Griselda N. Serrano, George G. Zhanel, Frank Schweizer
ABSTRACT Previously reported d , l -lipo-α-peptides and their lipo-β-peptide counterparts (C16-KGGK, C16-KAAK, C16-KKKK, and C12-KLLK) were studied, and the lipo-β-peptides were found to retain antimicrobial activity. Likewise, no significant changes in anti...... hiện toàn bộ
Substantial Targeting Advantage Achieved by Pulmonary Administration of Colistin Methanesulfonate in a Large-Animal Model
Antimicrobial Agents and Chemotherapy - Tập 61 Số 1 - 2017
Cornelia B. Landersdorfer, Tri‐Hung Nguyen, Linh Thuy Lieu, Gary Nguyen, Robert J. Bischof, Els Meeusen, Jian Li, Roger L. Nation, Michelle P. McIntosh
ABSTRACT Colistin, administered as its inactive prodrug colistin methanesulfonate (CMS), is often used in multidrug-resistant Gram-negative pulmonary infections. The CMS and colistin pharmacokinetics in plasma and epithelial lining fluid (ELF) following intravenous and pulmonary dosing have not been evaluated in a large-animal model with pulmonary archite...... hiện toàn bộ
Limited Polymorphism in the Dihydropteroate Synthetase Gene ( dhps ) of Plasmodium vivax Isolates from Thailand
Antimicrobial Agents and Chemotherapy - Tập 49 Số 10 - Trang 4393-4395 - 2005
Mallika Imwong, Sasithon Pukrittayakamee, Qin Cheng, Catrin E. Moore, Arnaud Fontanet, Georges Snounou, Nicholas J. White, Nicholas Day
ABSTRACT The dhps sequences of 55 Plasmodium vivax isolates (39 from Thailand and 16 from elsewhere) revealed mutant Pv dhps at codons 383 and/or 553 (A → G) in 33 isolates, all from Thailand...... hiện toàn bộ
Sulfadoxine Resistance in Plasmodium vivax Is Associated with a Specific Amino Acid in Dihydropteroate Synthase at the Putative Sulfadoxine-Binding Site
Antimicrobial Agents and Chemotherapy - Tập 48 Số 6 - Trang 2214-2222 - 2004
Michael Korsinczky, Ayşegül Taylan Özkan, Nanhua Chen, Joanne Baker, Jetsumon Sattabongkot, Qin Cheng
ABSTRACT Sulfadoxine is predominantly used in combination with pyrimethamine, commonly known as Fansidar, for the treatment of Plasmodium falciparum . This combination is usually less effective against Plasmodium vivax , probably due to the i...... hiện toàn bộ
Evidence for the generation of active oxygen by isoniazid treatment of extracts of Mycobacterium tuberculosis H37Ra
Antimicrobial Agents and Chemotherapy - Tập 27 Số 3 - Trang 404-407 - 1985
H. A. Shoeb, B. U. Bowman, Abramo C. Ottolenghi, Aristide Merola
Crude extracts of Mycobacterium tuberculosis H37Ra, an isonicotinic acid hydrazide (isoniazid) (INH)-susceptible strain which has peroxidase activity, catalyzed the production of catechol from phenol in the presence of INH and H2O2 as shown by the development of the 444-nm absorption peak of oxidized catechol product. Extracts of the INH-resistant strain of M. tuberculosis H37Ra, which has...... hiện toàn bộ
Scanning Electron Microscopy of the H37Ra Strain of Mycobacterium tuberculosis Exposed to Isoniazid
Antimicrobial Agents and Chemotherapy - Tập 4 Số 1 - Trang 62-65 - 1973
K. Takayama, Lynn Wang, R. S. Merkal
The morphology of cells of the H37Ra strain of Mycobacterium tuberculosis exposed to 0.5 μg of isonicotinic acid hydrazide (isoniazid) per ml was examined by scanning electron microscopy (SEM). Cells that were exposed to isoniazid for 3 h showed no detectable change, whereas cells exposed to the drug for 24 h exhibited diverse...... hiện toàn bộ
Enzymatic and nonenzymatic superoxide-generating reactions of isoniazid
Antimicrobial Agents and Chemotherapy - Tập 27 Số 3 - Trang 408-412 - 1985
H. A. Shoeb, B. U. Bowman, Abramo C. Ottolenghi, Aristide Merola
During the course of horseradish peroxidase-mediated oxidation of either o-dianisidine or 2-2'-azino-di(3-ethyl-benzthiazoline-6-sulfonic acid) (ABTS), no O2 consumption took place. When isonicotinic acid hydrazide (isoniazid) (INH) was included in the reaction mixture, O2 was consumed in amounts linearly related to the INH concentration. Nicotinic acid hydrazide at equimolar concentration...... hiện toàn bộ
Analysis of the oxyR-ahpC region in isoniazid-resistant and -susceptible Mycobacterium tuberculosis complex organisms recovered from diseased humans and animals in diverse localities
Antimicrobial Agents and Chemotherapy - Tập 41 Số 3 - Trang 600-606 - 1997
Srinand Sreevatsan, Xi Pan, Y. Zhang, Vojo Deretić, James M. Musser
Automated DNA sequencing was used to analyze the oxyR-ahpC region in 229 Mycobacterium tuberculosis complex isolates recently recovered from diseased humans and animals. The entire 1,221-bp region was studied in 118 isolates, and 111 other isolates were sequenced for oxyR, ahpC, or the 105-bp oxyR-ahpC intergenic region. The sample included isoniazid (INH)-susceptible and -resistant organi...... hiện toàn bộ
Tổng số: 720   
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 10