Annual Review of Physiology
SCOPUS (1946-2023)SCIE-ISI
0066-4278
1545-1585
Mỹ
Cơ quản chủ quản: Annual Reviews Inc. , ANNUAL REVIEWS
Lĩnh vực:
Physiology
Các bài báo tiêu biểu
Short-Term Synaptic Plasticity ▪ Abstract Synaptic transmission is a dynamic process. Postsynaptic responses wax and wane as presynaptic activity evolves. This prominent characteristic of chemical synaptic transmission is a crucial determinant of the response properties of synapses and, in turn, of the stimulus properties selected by neural networks and of the patterns of activity generated by those networks. This rev... ... hiện toàn bộ
Tập 64 Số 1 - Trang 355-405 - 2002
HEAT-SHOCK PROTEINS, MOLECULAR CHAPERONES, AND THE STRESS RESPONSE: Evolutionary and Ecological Physiology▪ Abstract Molecular chaperones, including the heat-shock proteins (Hsps), are a ubiquitous feature of cells in which these proteins cope with stress-induced denaturation of other proteins. Hsps have received the most attention in model organisms undergoing experimental stress in the laboratory, and the function of Hsps at the molecular and cellular level is becoming well understood in th... ... hiện toàn bộ
Tập 61 Số 1 - Trang 243-282 - 1999
Macrophages, Inflammation, and Insulin ResistanceObesity induces an insulin-resistant state in adipose tissue, liver, and muscle and is a strong risk factor for the development of type 2 diabetes mellitus. Insulin resistance in the setting of obesity results from a combination of altered functions of insulin target cells and the accumulation of macrophages that secrete proinflammatory mediators. At the molecular level, insulin resistance... ... hiện toàn bộ
Tập 72 Số 1 - Trang 219-246 - 2010
Aging, Cellular Senescence, and CancerFor most species, aging promotes a host of degenerative pathologies that are characterized by debilitating losses of tissue or cellular function. However, especially among vertebrates, aging also promotes hyperplastic pathologies, the most deadly of which is cancer. In contrast to the loss of function that characterizes degenerating cells and tissues, malignant (cancerous) cells must acqui... ... hiện toàn bộ
Tập 75 Số 1 - Trang 685-705 - 2013
Macrophage PolarizationMacrophage polarization refers to how macrophages have been activated at a given point in space and time. Polarization is not fixed, as macrophages are sufficiently plastic to integrate multiple signals, such as those from microbes, damaged tissues, and the normal tissue environment. Three broad pathways control polarization: epigenetic and cell survival pathways that prolong or shorten ma... ... hiện toàn bộ
Tập 79 Số 1 - Trang 541-566 - 2017
ENDOCRINOLOGY OF THE STRESS RESPONSE ▪ Abstract The stress response is subserved by the stress system, which is located both in the central nervous system and the periphery. The principal effectors of the stress system include corticotropin-releasing hormone (CRH); arginine vasopressin; the proopiomelanocortin-derived peptides α-melanocyte-stimulating hormone and β-endorphin, the glucocorticoids; and the catecholamines nore... ... hiện toàn bộ
Tập 67 Số 1 - Trang 259-284 - 2005
Synchronization of Cortical Activity and its Putative Role in Information Processing and Learning
Tập 55 Số 1 - Trang 349-374 - 1993
Traffic Signals on Endothelium for Lymphocyte Recirculation and Leukocyte Emigration
Tập 57 Số 1 - Trang 827-872 - 1995