Annual Review of Physiology

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Mechanotransduction
Annual Review of Physiology - Tập 54 Số 1 - Trang 135-152 - 1992
Andrew S. French
ION CHANNELS OF NOCICEPTION
Annual Review of Physiology - Tập 61 Số 1 - Trang 835-856 - 1999
Edwin W. McCleskey, Michael S. Gold
▪ Abstract  Nociceptors are the first cells in the series of neurons that lead to the sensation of pain. The essential functions of nociceptors—transducing noxious stimuli into depolarizations that trigger action potentials, conducting the action potentials from the peripheral sensory site to the synapse in the central nervous system, and converting the action potentials into neurotransmit...... hiện toàn bộ
Structure and Function of Cyclic Nucleotide-Dependent Protein Kinases
Annual Review of Physiology - Tập 56 Số 1 - Trang 237-272 - 1994
Sharron H. Francis, Jackie D. Corbin
Comparative Physiology: Pineal Gland
Annual Review of Physiology - Tập 35 Số 1 - Trang 305-328 - 1973
R J Reiter
Electrophysiology of Neuroglia
Annual Review of Physiology - Tập 37 Số 1 - Trang 163-190 - 1975
George G. Somjen
Phosphate Transporters and Their Function
Annual Review of Physiology - Tập 75 Số 1 - Trang 535-550 - 2013
Jürg Biber, Nati Hernando, Ian C. Forster
Plasma phosphate concentration is maintained within a relatively narrow range by control of renal reabsorption of filtered inorganic phosphate (Pi). Pi reabsorption is a transcellular process that occurs along the proximal tubule. Pi flux at the apical (luminal) brush border membrane represents the rate-limiting step and is me...... hiện toàn bộ
Aromatase—A Brief Overview
Annual Review of Physiology - Tập 64 Số 1 - Trang 93-127 - 2002
Evan R. Simpson, Colin D. Clyne, Gary Rubin, Wah Chin Boon, Kirsten Robertson, Kara Britt, Caroline J. Speed, Margaret E.E. Jones
▪ Abstract  There is growing awareness that androgens and estrogens have general metabolic roles that are not directly involved in reproductive processes. These include actions on vascular function, lipid and carbohydrate metabolism, as well as bone mineralization and epiphyseal closure in both sexes. In postmenopausal women, as in men, estrogen is no longer solely an endocrine factor but ...... hiện toàn bộ
Insulin Receptor Knockout Mice
Annual Review of Physiology - Tập 65 Số 1 - Trang 313-332 - 2003
Tadahiro Kitamura, C. Ronald Kahn, Domenico Accili
▪ Abstract  To examine the role of the insulin receptor in fuel homeostasis, we and others have carried out genetic ablation studies in mice. Mice lacking insulin receptors are born with normal features, but develop early postnatal diabetes and die of ketoacidosis. In contrast, mice lacking insulin receptors in specific cell types as a result of conditional mutagenesis develop mild metabol...... hiện toàn bộ
Chloride in Vesicular Trafficking and Function
Annual Review of Physiology - Tập 75 Số 1 - Trang 453-477 - 2013
Tobias Stauber, Thomas J. Jentsch
Luminal acidification is of pivotal importance for the physiology of the secretory and endocytic pathways and its diverse trafficking events. Acidification by the proton-pumping V-ATPase requires charge compensation by counterion currents that are commonly attributed to chloride. The molecular identification of intracellular chloride transporters and the improvement of methodologies for m...... hiện toàn bộ
Macrophage Polarization
Annual Review of Physiology - Tập 79 Số 1 - Trang 541-566 - 2017
Peter J. Murray
Macrophage polarization refers to how macrophages have been activated at a given point in space and time. Polarization is not fixed, as macrophages are sufficiently plastic to integrate multiple signals, such as those from microbes, damaged tissues, and the normal tissue environment. Three broad pathways control polarization: epigenetic and cell survival pathways that prolong or shorten ma...... hiện toàn bộ
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