Annual Review of Immunology

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The Regulation and Expression of c-myc in Normal and Malignant Cells
Annual Review of Immunology - Tập 4 Số 1 - Trang 317-338 - 1986
Kathleen Kelly, Ulrich Siebenlist
The Cell Biology of Macrophage Activation
Annual Review of Immunology - Tập 2 Số 1 - Trang 283-318 - 1984
Dolph O. Adams, Thomas A. Hamilton
Pathways of Antigen Processing
Annual Review of Immunology - Tập 31 Số 1 - Trang 443-473 - 2013
Janice S. Blum, Pamela A. Wearsch, Peter Cresswell
T cell recognition of antigen-presenting cells depends on their expression of a spectrum of peptides bound to major histocompatibility complex class I (MHC-I) and class II (MHC-II) molecules. Conversion of antigens from pathogens or transformed cells into MHC-I- and MHC-II-bound peptides is critical for mounting protective T cell responses, and similar processing of self proteins is necess...... hiện toàn bộ
Genes of the Major Histocompatibility Complex of the Mouse
Annual Review of Immunology - Tập 1 Số 1 - Trang 529-568 - 1983
Leroy Hood, Michael Steinmetz, Bernard Malissen
BCL-2 FAMILY: Regulators of Cell Death
Annual Review of Immunology - Tập 16 Số 1 - Trang 395-419 - 1998
Debra T. Chao, Stanley J. Korsmeyer
▪ Abstract  An expanding family of BCL-2 related proteins share homology, clustered within four conserved regions, namely BCL-2 homology (BH1-4) domains, which control the ability of these proteins to dimerize and function as regulators of apoptosis. Moreover, BCL-XL, BCL-2, and BAX can form ion-conductive pores in artificial membranes. The BCL-2 family, comprised of b...... hiện toàn bộ
DEVELOPMENT OF HUMAN LYMPHOID CELLS
Annual Review of Immunology - Tập 24 Số 1 - Trang 287-320 - 2006
Bianca Blom, Hergen Spits
The lymphocytes, T, B, and NK cells, and a proportion of dendritic cells (DCs) have a common developmental origin. Lymphocytes develop from hematopoietic stem cells via common lymphocyte and various lineage-restricted precursors. This review discusses the current knowledge of human lymphocyte development and the phenotypes and functions of the rare intermediate populations that together fo...... hiện toàn bộ
Transmission of Signals from the T Lymphocyte Antigen Receptor to the Genes Responsible for Cell Proliferation and Immune Function: The Missing Link
Annual Review of Immunology - Tập 8 Số 1 - Trang 421-452 - 1990
Katharine S. Ullman, Jeffrey P. Northrop, C L Verweij, Robert H. Crabtree
The Inflammasomes: Guardians of the Body
Annual Review of Immunology - Tập 27 Số 1 - Trang 229-265 - 2009
Fabio Martinon, Annick Mayor, Michael McDermott
The innate immune system relies on its capacity to rapidly detect invading pathogenic microbes as foreign and to eliminate them. The discovery of Toll-like receptors (TLRs) provided a class of membrane receptors that sense extracellular microbes and trigger antipathogen signaling cascades. More recently, intracellular microbial sensors have been identified, including NOD-like receptors (NL...... hiện toàn bộ
Antigen Recognition by Class I-Restricted T Lymphocytes
Annual Review of Immunology - Tập 7 Số 1 - Trang 601-624 - 1989
Alain Townsend, Helen Bodmer
Lpr and gld: Single Gene Models of Systemic Autoimmunity and Lymphoproliferative Disease
Annual Review of Immunology - Tập 9 Số 1 - Trang 243-269 - 1991
Philip L. Cohen, Robert A. Eisenberg
The autosomal recessive lpr and gld genes induce in mice multiple autoantibodies and the progressive accumulation of large numbers of non-malignant CD4- CD8- T lymphocytes. The clinical syndromes and immune abnormalities associated with these two nonallelic genes are nearly identical and are also highly dependent on background genes. MRL/lpr mice ...... hiện toàn bộ
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