American Journal of Reproductive Immunology

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Trophoblast Induces Monocyte Differentiation Into CD14+/CD16+ Macrophages
American Journal of Reproductive Immunology - Tập 72 Số 3 - Trang 270-284 - 2014
Paulomi Aldo, Karen Racicot, Vinicius Craviero, Seth Guller, Roberto Romero, Gil Mor
ProblemDuring early pregnancy, macrophages and trophoblast come into close contact during placenta development, and regulated cross talk between these cellular compartments is crucial for maintaining a healthy pregnancy. As trophoblast cells constitutively secrete many chemokines and cytokines, we hypothesize that trophoblast‐secreted factors can differen...... hiện toàn bộ
Monocytes from Pregnant Women with Pre-Eclampsia are Polarized to a M1 Phenotype
American Journal of Reproductive Immunology - Tập 72 Số 1 - Trang 5-13 - 2014
Leonardo Teixeira Lopes de Medeiros, José Carlos Peraçoli, Camila Ferreira Bannwart Castro, Mariana Romão‐Veiga, Ingrid C. Weel, Márjorie de Assis Golim, Leandro G. Oliveira, Cilmery Suemi Kurokawa, Vera Therezinha Medeiros Borges, Maria Terezinha Serrão Peraçoli
Expression of Fas‐Fas Ligand in Murine Testis
American Journal of Reproductive Immunology - Tập 42 Số 6 - Trang 381-388 - 1999
Ji Xu, Xiang Li, Etsuko Mori, Mao Wu Guo, Ichiro Matsuda, Hirohito Takaichi, Takashi Amano, Tsuneatsu Mori
Xu JP, Li X, Mori E, Guo MW, Matsuda I, Takaichi H, Amano T, Mori T. Expression of Fas‐Fas ligand in murine testis. AJRI 1999; 42:381–388 © Munksgaard, CopenhagenPROBLEM: During spermatogenesis, it has been suggested that the number of germ cells to be matured is regulated and restricted through the apoptotic mechanism....... hiện toàn bộ
Patterns of peripheral cytokine expression during pregnancy in two cohorts and associations with inflammatory markers in cord blood
American Journal of Reproductive Immunology - Tập 76 Số 5 - Trang 406-414 - 2016
Kharah M. Ross, Gregory E. Miller, Jennifer F. Culhane, William A. Grobman, Hyagriv N. Simhan, Pathik D. Wadhwa, Douglas E. Williamson, Thomas W. McDade, Claudia Buß, Sonja Entringer, Emma K. Adam, Sameen Qadir, Lauren Keenan‐Devlin, Adam K.K. Leigh, Ann Borders
Longitudinal Profiling of Inflammatory Cytokines and C‐reactive Protein during Uncomplicated and Preterm Pregnancy
American Journal of Reproductive Immunology - Tập 72 Số 3 - Trang 326-336 - 2014
Kelly K. Ferguson, Thomas F. McElrath, Yin‐Hsiu Chen, Bhramar Mukherjee, John D. Meeker
ProblemPrevious studies have investigated the utility of inflammation markers as predictors of preterm birth, but none have compared trends in levels between uncomplicated and preterm pregnancy.Method of studyWe explored longitudinal changes in plasma cytokines, including ... hiện toàn bộ
Regulation of Major Histocompatibility Complex and TAP Gene Products in Preimplantation Mouse Stage Embryos
American Journal of Reproductive Immunology - Tập 40 Số 3 - Trang 165-171 - 1998
Joanne C. Cooper, Nelson Fernández, Etienne Joly, Gill Dealtry
PROBLEM: To determine the ontogeny of major histocompatibility complex (MHC) expression and TAP products in mouse embryos.METHOD OF STUDY: mRNAs encoding MHC and associated molecules were identified by reverse transcriptase‐polymerase chain reaction, and the protein products were localized by confocal microscopy.RESULTS: mRNAs encoding class Ia (H‐2D... hiện toàn bộ
Influence of the Estrous Cycle on the Presence and Distribution of Immune Cells in the Rat Reproductive Tract
American Journal of Reproductive Immunology - Tập 39 Số 3 - Trang 209-216 - 1998
Charu Kaushic, Elaine Frauendorf, Richard M. Rossoll, Jan Richardson, Charles R. Wira
PROBLEM: Previous studies have shown that the uterus and vagina contain cells that can present antigen to ovalbumin‐specific T‐cells. The objective of the present study was to systematically characterize the immune cells [major histocompatibility complex (MHC) class‐II+, macrophages, granulocytes, dendritic cells, and CD8+ cells] present in the uterus and vagina of the rat and to examine t...... hiện toàn bộ
Obesity and metabolic syndrome associated with systemic inflammation and the impact on the male reproductive system
American Journal of Reproductive Immunology - Tập 82 Số 5 - 2019
Kristian Leisegang, Ralf Henkel, Ashok Agarwal
AbstractObesity and metabolic syndrome (MetS) are global epidemics, driven by an obesogenic environment. This is mediated by complex underlying pathophysiology, in which chronic inflammation is an important aetiological and mechanistic phenomenon. A shift towards a subclinical TH1–lymphocyte mediated innate and chronic inflammatory response is ...... hiện toàn bộ
GLP‐1 Receptor Agonist Exenatide Attenuates the Detrimental Effects of Obesity on Inflammatory Profile in Testis and Sperm Quality in Mice
American Journal of Reproductive Immunology - Tập 74 Số 5 - Trang 457-466 - 2015
Erhong Zhang, Fen Xu, Hua Liang, Jinhua Yan, Haixia Xu, Zhuo Li, Xingqiao Wen, Jianping Weng
ProblemMale obesity has been linked to subfecundity. This study is to investigate the effects of GLP‐1 receptor (GLP‐1R) agonist exenatide on sperm quality in high‐fat diet (HFD)‐induced obese mice.Method of studyAfter 12 weeks of chow diet (CD) or HFD challenge, mice on HFD were allocated to ...... hiện toàn bộ
Oxidative Stress: Placenta Function and Dysfunction
American Journal of Reproductive Immunology - Tập 76 Số 4 - Trang 258-271 - 2016
Fan Wu, Fu‐Ju Tian, Yi Lin, Wangming Xu
During pregnancy, the placenta is a site of active oxygen metabolism that continuously generates oxidative stress (OS). Overproduction of reactive oxygen species and reactive nitrogen species can destroy normal placental functions. Therefore, the feto‐placental unit generates abundant antioxidants to keep ... hiện toàn bộ
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