American Journal of Reproductive Immunology
SCIE-ISI SCOPUS (1980-1984,1989-2025)
1600-0897
1046-7408
Anh Quốc
Cơ quản chủ quản: WILEY , Wiley-Blackwell Publishing Ltd
Lĩnh vực:
ImmunologyObstetrics and GynecologyImmunology and AllergyReproductive Medicine
Phân tích ảnh hưởng
Các bài báo tiêu biểu
REVIEW ARTICLE: The Immune System in Pregnancy: A Unique Complexity
Tập 63 Số 6 - Trang 425-433 - 2010
Citation Mor G, Cardenas I. The immune system in pregnancy: a unique complexity.
Am J Reprod Immunol 2010AbstractPlacental immune response and its tropism for
specific viruses and pathogens affect the outcome of the pregnant woman’s
susceptibility to and severity of certain infectious diseases. The
generalization of pregnancy as a condition of immune suppression or increased
risk is misleading and...
REVIEW ARTICLE: Immunology of Pre‐Eclampsia
Tập 63 Số 6 - Trang 534-543 - 2010
Citation Redman CWG, Sargent IL. Immunology of Pre‐eclampsia. Am J Reprod
Immunol 2010Pre‐eclampsia develops in stages, only the last being the clinical
illness. This is generated by a non‐specific, systemic (vascular), inflammatory
response, secondary to placental oxidative stress and not by reactivity to fetal
alloantigens. However, maternal adaptation to fetal (paternal alloantigens) is
crucial...
Placental Cytokines and the Pathogenesis of Preeclampsia
Tập 37 Số 3 - Trang 240-249 - 1997
The authors explore the hypothesis that tumor necrosis factor‐α (TNF‐α) and
possibly other inflammatory cytokines are overproduced by the placenta in
response to local ischemia/hypoxia contributing to increased plasma levels, and
subsequent endothelial activation and dysfunction in the pregnancy disorder,
preeclampsia. It is widely held that inadequate trophoblast invasion and
physiologic remodeli...
Circulating Levels of Immunoreactive Cytokines in Women with Preeclampsia
Tập 40 Số 2 - Trang 102-111 - 1998
PROBLEM: Circulating inflammatory cytokines have been implicated in the
pathogenesis of preeclampsia. To test this hypothesis, we measured plasma levels
of immunoreactive tumor necrosis factor (TNF)‐α and ‐β, interleukin (IL)−1α and
‐β, and IL‐6 and −10 in women with preeclampsia, in women with transient
gestational hypertension, and throughout normal pregnancy.METHOD OF STUDY:
Enzyme‐linked immun...
The Role of Cytokines in Endometriosis*
Tập 49 Số 5 - Trang 285-296 - 2003
PROBLEM: To review the literature on the role of peritoneal cytokines in the
pathogenesis and endometriosis‐related infertility.METHODS OF STUDY: A MEDLINE
search was conducted by the key words of cytokine and endometriosis in the
English publications, and references identified within the identified papers
were also reviewed.RESULTS: Several cytokines including interleukin (IL)‐1, 6,
8, 10, tum...
Interferon Tau: A Novel Pregnancy Recognition Signal
Tập 37 Số 6 - Trang 412-420 - 1997
PROBLEM: Trophectoderm of ruminant conceptuses (embryo and associated membranes)
secretes tau interferons (IFNẗ) as the pregnancy recognition signal. How does it
act?METHOD: Review of current data.RESULTS: IFNt acts on uterine epithelium to
suppress transcription of the genes for estrogen receptor and oxytocin receptor.
This blocks development of the uterine luteolytic mechanism and, therefore,
re...
Changes in T, B, and NK Lymphocyte Subsets During and After Normal Pregnancy
Tập 37 Số 5 - Trang 368-377 - 1997
PROBLEM: Pregnancy affects the maternal immune system and the clinical course of
maternal diseases. Here we report the changes in the detailed lymphocyte subsets
of helper T cells, suppressor T cells, CD5+ B cells, T cell receptor (TCR)
αβ‐positive T cells (Tαβ cells), TCRαβ‐negative T cell (Tγδ cells), and others
during and after pregnancy through to one year postpartum, and discuss the
significa...
Mastitis and Fertility in Cattle – Possible Involvement of Inflammation or Immune Activation in Embryonic Mortality*
Tập 51 Số 4 - Trang 294-301 - 2004
Causes for pre‐implantation embryo loss, which can be as high as 50% or more of
fertilized embryos, are multifactorial and largely undescribed. Studies in
cattle using mastitis as a model indicate that one cause of early embryonic loss
is infectious disease or activation of immune responses at sites outside the
reproductive tract. Infection of the mammary gland in dairy cattle is associated
with a...
Luminal and Glandular Endometrial Epithelium Express Integrins Differentially Throughout the Menstrual Cycle: Implications for Implantation, Contraception, and Infertility
Tập 35 Số 3 - Trang 195-204 - 1996
PROBLEM: Integrins belong to a family of cell adhesion molecules that are
present on virtually all cells. The temporal and spatial expression of these
important proteins on the human endometrium suggests that certain integrins may
participate in the cascade of molecular events leading to successful
implantation.METHODS: Using immunohistochemistry, we studied the expression of
12 different integrin...
Angiogenesis and the Expression of Vascular Endothelial Growth Factor in Endometrium and Placenta
Tập 37 Số 1 - Trang 21-29 - 1997
PROBLEM: The demand for increased angiogenesis and microvascular permeability
during cyclical changes in the endometrium and during placentation raises the
possibility that aberrations in these events could lead to suboptimal
reproductive performance. However, relatively little is presently known
regarding the regulation of vascular growth and permeability in these
tissues.METHOD OF STUDY: This re...