REVIEW ARTICLE: The Immune System in Pregnancy: A Unique Complexity Tập 63 Số 6 - Trang 425-433 - 2010
Gil Mor, Ingrid Cardenas
Citation Mor G, Cardenas I. The immune system in pregnancy: a unique complexity. Am J Reprod Immunol 2010AbstractPlacental immune response and its tropism for specific viruses and pathogens affect the outcome of the pregnant woman’s susceptibility to and severity of certain infect...... hiện toàn bộ REVIEW ARTICLE: Immunology of Pre‐Eclampsia Tập 63 Số 6 - Trang 534-543 - 2010
Christopher W.G. Redman, Ian L. Sargent
Citation Redman CWG, Sargent IL. Immunology of Pre‐eclampsia. Am J Reprod Immunol 2010Pre‐eclampsia develops in stages, only the last being the clinical illness. This is generated by a non‐specific, systemic (vascular), inflammatory response, secondary to placental oxidative stress and not by reactivity to fetal alloantigens. However, maternal adapt...... hiện toàn bộ Placental Cytokines and the Pathogenesis of Preeclampsia Tập 37 Số 3 - Trang 240-249 - 1997
Kirk P. Conrad, Deborah Fairchild Benyo
The authors explore the hypothesis that tumor necrosis factor‐α (TNF‐α) and possibly other inflammatory cytokines are overproduced by the placenta in response to local ischemia/hypoxia contributing to increased plasma levels, and subsequent endothelial activation and dysfunction in the pregnancy disorder, preeclampsia. It is widely held that inadequate trophoblast invasion and physiologic ...... hiện toàn bộ Circulating Levels of Immunoreactive Cytokines in Women with Preeclampsia Tập 40 Số 2 - Trang 102-111 - 1998
Kirk P. Conrad, Theresa M. Miles, Deborah Fairchild Benyo
PROBLEM: Circulating inflammatory cytokines have been implicated in the pathogenesis of preeclampsia. To test this hypothesis, we measured plasma levels of immunoreactive tumor necrosis factor (TNF)‐α and ‐β, interleukin (IL)−1α and ‐β, and IL‐6 and −10 in women with preeclampsia, in women with transient gestational hypertension, and throughout normal pregnancy.METHOD OF S...... hiện toàn bộ The Role of Cytokines in Endometriosis* Tập 49 Số 5 - Trang 285-296 - 2003
Ming‐Yih Wu, Hong‐Nerng Ho
PROBLEM: To review the literature on the role of peritoneal cytokines in the pathogenesis and endometriosis‐related infertility.METHODS OF STUDY: A MEDLINE search was conducted by the key words of cytokine and endometriosis in the English publications, and references identified within the identified papers were also reviewed....... hiện toàn bộ Interferon Tau: A Novel Pregnancy Recognition Signal Tập 37 Số 6 - Trang 412-420 - 1997
Fuller W. Bazer, Thomas E. Spencer, Troy L. Ott
PROBLEM: Trophectoderm of ruminant conceptuses (embryo and associated membranes) secretes tau interferons (IFNẗ) as the pregnancy recognition signal. How does it act?METHOD: Review of current data.RESULTS: IFNt acts on uterine epithelium to suppress transcription of the genes for estrogen receptor and oxytocin receptor. This blocks development of the uteri...... hiện toàn bộ Changes in T, B, and NK Lymphocyte Subsets During and After Normal Pregnancy Tập 37 Số 5 - Trang 368-377 - 1997
Mikio Watanabe, Yoshinori Iwatani, T Kaneda, Yoh Hidaka, Nobuaki Mitsuda, Yasuhiko Morimoto, Nobuyuki Amino
PROBLEM: Pregnancy affects the maternal immune system and the clinical course of maternal diseases. Here we report the changes in the detailed lymphocyte subsets of helper T cells, suppressor T cells, CD5+ B cells, T cell receptor (TCR) αβ‐positive T cells (Tαβ cells), TCRαβ‐negative T cell (Tγδ cells), and others during and after pregnancy through to one year postpart...... hiện toàn bộ Angiogenesis and the Expression of Vascular Endothelial Growth Factor in Endometrium and Placenta Tập 37 Số 1 - Trang 21-29 - 1997
Donald S. Torry, Ronald J. Torry
PROBLEM: The demand for increased angiogenesis and microvascular permeability during cyclical changes in the endometrium and during placentation raises the possibility that aberrations in these events could lead to suboptimal reproductive performance. However, relatively little is presently known regarding the regulation of vascular growth and permeability in these tissues.... hiện toàn bộ