American Journal of Physiology - Regulatory Integrative and Comparative Physiology

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Highly sensitive index of sympathetic activity based on time-frequency spectral analysis of electrodermal activity
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 311 Số 3 - Trang R582-R591 - 2016
Hugo F. Posada-Quintero, John P. Florian, Álvaro D. Orjuela-Cañón, Ki H. Chon
Time-domain indices of electrodermal activity (EDA) have been used as a marker of sympathetic tone. However, they often show high variation between subjects and low consistency, which has precluded their general use as a marker of sympathetic tone. To examine whether power spectral density analysis of EDA can provide more consistent results, we recently performed a variety of sympathetic ...... hiện toàn bộ
Metabolic control of food intake and estrous cycles in Syrian hamsters. I. Plasma insulin and leptin
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 278 Số 2 - Trang R476-R485 - 2000
Jill E. Schneider, Robert M. Blum, George N. Wade
The “adipostat hypothesis” refers to the idea that circulating hormone concentrations reflect levels of body adiposity and act as signals to control food intake and reproduction. Implicit in the adipostatic hypothesis are the following two assumptions: 1) plasma levels of adipostatic hormones accurately reflect body fat content and 2) decreased plasma concentrations of adipostatic hormones...... hiện toàn bộ
Intradermal administration of ATP does not mitigate tyramine-stimulated vasoconstriction in human skin
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 298 Số 5 - Trang R1417-R1420 - 2010
Jonathan E. Wingo, R. Matthew Brothers, Juan Del Coso, Craig G. Crandall
Cutaneous vasodilation associated with whole-body heat stress occurs via withdrawal of adrenergic vasoconstriction and engagement of cholinergic “active” vasodilation, the latter of which attenuates cutaneous vasoconstrictor responsiveness. However, the precise neurotransmitter(s) responsible for this sympatholytic-like effect remain unknown. In skeletal muscle, ATP inhibits adrenergicall...... hiện toàn bộ
Separate and combined effects of KCa and KATP channel blockade with NOS inhibition on cutaneous vasodilation and sweating in older men during heat stress
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 317 Số 1 - Trang R113-R120 - 2019
Gregory W. McGarr, Naoto Fujii, Caroline M. Muia, Takeshi Nishiyasu, Glen P. Kenny
Our objective in this study was to examine the separate and combined effects of potassium (K+) channels and nitric oxide synthase (NOS) on cutaneous vasodilation and sweating in older men during rest and exercise in the heat. In 13 habitually active men (61 ± 4 yr), cutaneous vascular conductance and local sweat rate were assessed at six dorsal forearm skin sites cont...... hiện toàn bộ
Vitamin E at high doses improves survival, neurological performance, and brain mitochondrial function in aging male mice
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 289 Số 5 - Trang R1392-R1399 - 2005
Ana Navarro, Carmen Gómez, María-Jesús Sánchez-Pino, Hipolito J. Gonzalez, Manuel J. Bández, Alberto Boveris, Alberto Boveris
Male mice receiving vitamin E (5.0 g α-tocopherol acetate/kg of food) from 28 wk of age showed a 40% increased median life span, from 61 ± 4 wk to 85 ± 4 wk, and 17% increased maximal life span, whereas female mice equally supplemented exhibited only 14% increased median life span. The α-tocopherol content of brain and liver was 2.5-times and 7-times increased in male mice, respectively. V...... hiện toàn bộ
Renin receptor expression in human adipose tissue
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 292 Số 1 - Trang R274-R282 - 2007
Vincent Achard, Sandrine Boullu‐Ciocca, Raoul Desbrière, Geneviève Nguyen, Michel Grino
Adipose tissue synthesizes all components of the renin-angiotensin system. The renin receptor (RenR) is able, on renin binding, to increase its efficiency to generate angiotensin I from angiotensinogen. We demonstrate that RenR is specifically synthesized in the stromal portion of human adipose tissue in both isolated interadipocyte stromal cells and in stromal areas. RenR is expressed at...... hiện toàn bộ
ACE2 is expressed in mouse adipocytes and regulated by a high-fat diet
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 295 Số 3 - Trang R781-R788 - 2008
Manisha Gupte, Carine M. Boustany‐Kari, Kalyani G. Bharadwaj, Sean E. Thatcher, Victoria English, Lisa A. Cassis
Adipose tissue expresses components of the renin-angiotensin system (RAS). Angiotensin converting enzyme (ACE2), a new component of the RAS, catabolizes the vasoconstrictor peptide ANG II to form the vasodilator angiotensin 1-7 [ANG-(1-7)]. We examined whether adipocytes express ACE2 and its regulation by manipulation of the RAS and by high-fat (HF) feeding. ACE2 mRNA expression increased...... hiện toàn bộ
AT1-receptor antagonism reverses the blood pressure elevation associated with diet-induced obesity
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 289 Số 1 - Trang R181-R186 - 2005
Carine Boustany, David R. Brown, David C. Randall, Lisa A. Cassis
Previous studies in our laboratory demonstrated that rats exhibiting obesity in response to a moderately high-fat (MHF) diet developed hypertension associated with activation of the local and systemic renin-angiotensin system. In this study, we examined the effect of the angiotensin type 1 (AT1)-receptor antagonist, losartan, on blood pressure in obesity-prone (OP) and...... hiện toàn bộ
Micropuncture studies of the osmoregulation in the nauplius of Artemia salina
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 234 Số 5 - Trang R216-R222 - 1978
D. Russler, J. A. Mangos
The osmoregulation of the nauplius of the brine shrimp, Artemia salina, was investigated using micropuncture and microanalytical techniques. The naupliar body fluid, hemolymph was hyposmotic to and had lower Na concentrations than the suspending medium for the range of medium salinities from 80 to 4,900 mM NaCl. In medium containing 20 mM NaCl, the hemolymph was hyperosmotic to the medium...... hiện toàn bộ
Béo phì và sinh nhiệt liên quan đến việc tiêu thụ caffeine, ephedrine, capsaicin, và trà xanh Dịch bởi AI
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 292 Số 1 - Trang R77-R85 - 2007
K. Diepvens, Klaas R. Westerterp, Margriet S. Westerterp‐Plantenga
Tỷ lệ béo phì toàn cầu đã tăng đáng kể trong thập kỷ qua. Các phương pháp quản lý béo phì, bao gồm caffeine, ephedrine, capsaicin và trà xanh đã được đề xuất như là chiến lược giảm cân và duy trì cân nặng, vì chúng có thể làm tăng tiêu hao năng lượng và có khả năng chống lại sự giảm tốc độ chuyển hóa xuất hiện trong quá trình giảm cân. Sự kết hợp giữa caffeine và ephedrine đã chứng minh h...... hiện toàn bộ
#Béo phì #sinh nhiệt #caffeine #ephedrine #capsaicin #trà xanh #quản lý cân nặng #tiêu hao năng lượng #catecholamine #tùy chỉnh liều dùng #ức chế phosphodiesterase #tránh thừa cân #hệ thần kinh giao cảm #phân giải lipid #chuyển hóa
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