American Journal of Physiology - Regulatory Integrative and Comparative Physiology

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Simulations of light effects on the human circadian pacemaker: implications for assessment of intrinsic period
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 270 Số 1 - Trang R271-R282 - 1996
Elizabeth B. Klerman, Derk‐Jan Dijk, Richard E. Kronauer, Charles A. Czeisler
The sensitivity of the human circadian system to light has been the subject of considerable debate. Using computer simulations of a recent quantitative model for the effects of light on the human circadian system, we investigated these effects of light during different experimental protocols. The results of the simulations indicate that the nonuniform distribution over the circadian cycle...... hiện toàn bộ
Quercetin tăng cường sinh tổng hợp ty thể não và cơ bắp cũng như khả năng chịu đựng trong tập luyện Dịch bởi AI
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 296 Số 4 - Trang R1071-R1077 - 2009
John M. Davis, E. Angela Murphy, Martin D. Carmichael, Ben Davis
Quercetin là một trong những nhóm lớn các hợp chất flavonoid polyphenolic tự nhiên đang được nghiên cứu vì những lợi ích sức khỏe rộng rãi của chúng. Những lợi ích này thường được cho là do sự kết hợp của hoạt động chống oxy hóa và kháng viêm, nhưng các bằng chứng in vitro gần đây cho thấy rằng sự cải thiện sinh tổng hợp ty thể có thể đóng một vai trò quan trọng. Hơn nữa, các tác động in ...... hiện toàn bộ
Relationships between aerobic and anaerobic energy production in turtle brain in situ
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 247 Số 4 - Trang R740-R744 - 1984
Peter L. Lutz, P. M. McMahon, Myron Rosenthal, Thomas J. Sick
To define the relationships between brain mitochondrial activity and high-energy intermediates in the turtle, brains were frozen in situ at times determined by the reduction-oxidation status of cytochrome a,a3. Increases in brain lactate indicated that transition to anaerobiosis occurred while oxidative reactions were still ongoing during hypoxia and that the signal for anaerobiosis is no...... hiện toàn bộ
Highly sensitive index of sympathetic activity based on time-frequency spectral analysis of electrodermal activity
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 311 Số 3 - Trang R582-R591 - 2016
Hugo F. Posada-Quintero, John P. Florian, Álvaro D. Orjuela-Cañón, Ki H. Chon
Time-domain indices of electrodermal activity (EDA) have been used as a marker of sympathetic tone. However, they often show high variation between subjects and low consistency, which has precluded their general use as a marker of sympathetic tone. To examine whether power spectral density analysis of EDA can provide more consistent results, we recently performed a variety of sympathetic ...... hiện toàn bộ
The molecular basis of aerobic metabolic remodeling differs between oxidative muscle and liver of threespine sticklebacks in response to cold acclimation
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 299 Số 1 - Trang R352-R364 - 2010
Julieanna I. Orczewska, Götz Hartleben, Kristin M. O’Brien
We sought to determine the molecular basis of elevations in aerobic metabolic capacity in the oxidative muscle and liver of Gasterosteus aculeatus in response to cold acclimation. Fishes were cold- or warm-acclimated for 9 wk and harvested on days 1, 2, and 3 and weeks 1, 4, and 9 of cold acclimation at 8°C, and on day 1 and week 9 of warm acclimation at 20°C. Mitochondrial volume density ...... hiện toàn bộ
A3adenosine receptor activation decreases mortality and renal and hepatic injury in murine septic peritonitis
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 291 Số 4 - Trang R959-R969 - 2006
H. Thomas Lee, Mihwa Kim, Jin Deok Joo, George Gallos, Jiang‐Fan Chen, Charles W. Emala
The role of A3adenosine receptors (ARs) in sepsis and inflammation is controversial. In this study, we determined the effects of A3AR modulation on mortality and hepatic and renal dysfunction in a murine model of sepsis. To induce sepsis, congenic A3AR knockout mice (A3AR KO) and wild-type control (A... hiện toàn bộ
Locomotor muscle fatigue increases cardiorespiratory responses and reduces performance during intense cycling exercise independently from metabolic stress
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 294 Số 3 - Trang R874-R883 - 2008
Samuele Marcora, Andrea Bosio, Helma M. de Morree
Locomotor muscle fatigue, defined as an exercise-induced reduction in maximal voluntary force, occurs during prolonged exercise, but its effects on cardiorespiratory responses and exercise performance are unknown. In this investigation, a significant reduction in locomotor muscle force (−18%, P < 0.05) was isolated from the metabolic stress usually associated with fatiguing exercise usi...... hiện toàn bộ
Seasonal changes in serum leptin, food intake, and body weight in photoentrained woodchucks
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 281 Số 3 - Trang R951-R959 - 2001
Patrick W. Concannon, K.D. Levac, Richard E. Rawson, Bud C. Tennant, André Bensadoun
Male woodchucks ( Marmota monax) were maintained in northern vs. southern hemisphere photoperiods, provided feed and water ad libitum, and evaluated every 2 wk for 23 mo for body weight, absolute and relative food intake, body temperature, serum testosterone, and serum concentrations of leptin measured using an anti-mouse leptin enzyme-linked immunoassay. During late spring and summer, bod...... hiện toàn bộ
Metabolic control of food intake and estrous cycles in Syrian hamsters. I. Plasma insulin and leptin
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 278 Số 2 - Trang R476-R485 - 2000
Jill E. Schneider, Robert M. Blum, George N. Wade
The “adipostat hypothesis” refers to the idea that circulating hormone concentrations reflect levels of body adiposity and act as signals to control food intake and reproduction. Implicit in the adipostatic hypothesis are the following two assumptions: 1) plasma levels of adipostatic hormones accurately reflect body fat content and 2) decreased plasma concentrations of adipostatic hormones...... hiện toàn bộ
Intradermal administration of ATP does not mitigate tyramine-stimulated vasoconstriction in human skin
American Journal of Physiology - Regulatory Integrative and Comparative Physiology - Tập 298 Số 5 - Trang R1417-R1420 - 2010
Jonathan E. Wingo, R. Matthew Brothers, Juan Del Coso, Craig G. Crandall
Cutaneous vasodilation associated with whole-body heat stress occurs via withdrawal of adrenergic vasoconstriction and engagement of cholinergic “active” vasodilation, the latter of which attenuates cutaneous vasoconstrictor responsiveness. However, the precise neurotransmitter(s) responsible for this sympatholytic-like effect remain unknown. In skeletal muscle, ATP inhibits adrenergicall...... hiện toàn bộ
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