American Chemical Society (ACS)

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The influence of material and mesh characteristics on transmission mode desorption electrospray ionization
American Chemical Society (ACS) - Tập 20 - Trang 584-592 - 2009
Joseph E. Chipuk, Jennifer S. Brodbelt
Catalytic mechanism of Golgi-resident human tyrosylprotein sulfotransferase-2: A mass spectrometry approach
American Chemical Society (ACS) - Tập 21 Số 9 - Trang 1633-1642 - 2010
Lieza M. Danan, Zhihao Yu, Peter J. Ludden, Wenbao Jia, Kevin L. Moore, Julie A. Leary
Comparison of LC and LC/MS methods for quantifying N-glycosylation in recombinant IgGs
American Chemical Society (ACS) - Tập 19 - Trang 1643-1654 - 2011
Sandipan Sinha, Gary Pipes, Elizabeth M. Topp, Pavel V. Bondarenko, Michael J. Treuheit, Himanshu S. Gadgil
High-performance liquid chromatography (LC) and liquid chromatography/electrospray ionization time-of-flight mass spectrometry (LC/ESI-MS) methods with various sample preparation schemes were compared for their ability to identify and quantify glycoforms in two different production lots of a recombinant monoclonal IgG1 antibody. IgG1s contain a conserved N-glycosylation site in the fragment crysta...... hiện toàn bộ
Rapid and Definitive Analysis of In Vitro DNA Methylation by Nano-electrospray Ionization Mass Spectrometry
American Chemical Society (ACS) - Tập 30 Số 11 - Trang 2335-2346 - 2019
Hiroshi Ushijima, Rena Maekawa, Eri Igarashi, Satoko Akashi
High-field fourier transform ion cyclotron resonance mass spectrometry for simultaneous trapping and gas-phase hydrogen/deuterium exchange of peptide ions
American Chemical Society (ACS) - Tập 9 - Trang 1012-1019 - 1998
Michael A. Freitas, Christopher L. Hendrickson, Mark R. Emmett, Alan G. Marshall
Gas-phase hydrogen/deuterium exchange of D2O with [M+H]+ ions of angiotensin II, angiotensin I, [Sar1]-angiotensin II, bradykinin, des-Arg1-bradykinin, des-Arg9-bradykinin, luteinizing hormone releasing hormone (LH-RH), and substance P has been examined by Fourier transform ion cyclotron resonance mass spectrometry at 9.4 tesla. Because the FTICR dynamic range increases quadratically with magnetic...... hiện toàn bộ
UV Photodissociation Action Spectroscopy of Haloanilinium Ions in a Linear Quadrupole Ion Trap Mass Spectrometer
American Chemical Society (ACS) - Tập 24 - Trang 932-940 - 2013
Christopher S. Hansen, Benjamin B. Kirk, Stephen J. Blanksby, Richard. A. J. O’Hair, Adam J. Trevitt
UV–vis photodissociation action spectroscopy is becoming increasingly prevalent because of advances in, and commercial availability of, ion trapping technologies and tunable laser sources. This study outlines in detail an instrumental arrangement, combining a commercial ion-trap mass spectrometer and tunable nanosecond pulsed laser source, for performing fully automated photodissociation action sp...... hiện toàn bộ
The Ionization Mechanisms in Direct and Dopant-Assisted Atmospheric Pressure Photoionization and Atmospheric Pressure Laser Ionization
American Chemical Society (ACS) - Tập 25 - Trang 1870-1881 - 2014
Tiina J. Kauppila, Hendrik Kersten, Thorsten Benter
A novel, gas-tight API interface for gas chromatography–mass spectrometry was used to study the ionization mechanism in direct and dopant-assisted atmospheric pressure photoionization (APPI) and atmospheric pressure laser ionization (APLI). Eight analytes (ethylbenzene, bromobenzene, naphthalene, anthracene, benzaldehyde, pyridine, quinolone, and acridine) with varying ionization energies (IEs) an...... hiện toàn bộ
Electrospray ionization mass spectrometry and hydrogen/deuterium exchange for probing the interaction of calmodulin with calcium
American Chemical Society (ACS) - Tập 10 - Trang 711-718 - 1999
Olga Nemirovskiy, Daryl E. Giblin, Michael L. Gross
The extent of H/D exchange of the protein calmodulin in solution was monitored by mass spectrometry following electrospray ionization (ESI) of the protein. In the absence of Ca2+, approximately 115 protons are exchanged for deuteriums after 60 min. As the calmodulin is titrated with Ca2+, the extent of exchange decreases significantly (i.e., by 24 protons), indicating Ca2+-induced folding of the p...... hiện toàn bộ
Rapid identification of stress-related fingerprint from whole bacterial cells of Bifidobacterium lactis using matrix assisted laser desorption/ionization mass spectrometry
American Chemical Society (ACS) - Tập 15 - Trang 1222-1227 - 2004
Laure F. Marvin-Guy, Stephan Parche, Sandrine Wagnière, Julie Moulin, Ralf Zink, Martin Kussmann, Laurent B. Fay
Whole cells of Bifidobacterium lactis were analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS). Characteristic and reproducible mass spectra were obtained in the mass range from 6 to 19 kDa. After several days of bacterial cell storage at 4 °C (D0, D2, and D6), only minor signal differences were observed. Under identical and reproducible condition...... hiện toàn bộ
Mass Spectrometry Analysis of 2-Nitrophenylhydrazine Carboxy Derivatized Peptides
American Chemical Society (ACS) - Tập 22 - Trang 1958-1967 - 2011
Junmei Zhang, Rowaida Al-Eryani, Haydn L. Ball
Peptides with two or more basic residues, including those with post-translational modifications (PTMs), such as methylation and phosphorylation, can be highly hydrophilic and, therefore, are often difficult to be retained on a reversed-phase (RP) column. In addition, these highly hydrophilic peptides may carry two or more positive charges, which often fragment poorly upon collisionally activated d...... hiện toàn bộ
Tổng số: 5,709   
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