Addiction Biology

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Expression of Concern: The effects of melatonin supplementation on mental health, metabolic and genetic profiles in patients under methadone maintenance treatment
Addiction Biology - Tập 24 Số 4 - Trang 754-764 - 2019
Amir Ghaderi, Hamid Reza Banafshe, Naghmeh Mirhosseini, Maryam Motmaen, Fatemeh Mehrzad, Fereshteh Bahmani, Esmat Aghadavod, Mohammad Alì Mansournia, Rüssel J. Reiter, Mohammad‐Amin Karimi, Zatollah Asemi
AbstractThis investigation was designed to determine the effect of melatonin supplementation on mental health parameters, metabolic and genetic profiles in patients under methadone maintenance treatment (MMT). This randomized, double‐blind, placebo‐controlled, clinical trial was conducted among 54 patients under MMT. Participants were randomly allocated to receive ...... hiện toàn bộ
Cocaine use severity and cerebellar gray matter are associated with reversal learning deficits in cocaine-dependent individuals
Addiction Biology - Tập 20 Số 3 - Trang 546-556 - 2015
Laura Moreno-López, José C. Perales, Dana Van Son, Natalia Albein‐Urios, Carles Soriano‐Mas, José Miguel Martínez González, Reínout W. Wiers, Antonio Verdejo‐García
Nicotine self‐administration reverses cognitive deficits in a rat model for schizophrenia
Addiction Biology - Tập 23 Số 2 - Trang 620-630 - 2018
Uta Waterhouse, Katharine A. Brennan, Bart Ellenbroek
AbstractHigh comorbidity between schizophrenia and tobacco addiction has been well established. Explanatory theories include nicotine as a cognitive enhancer ameliorating symptoms of schizophrenia and underlying shared substrates increasing susceptibility to addiction in these individuals. To test these non‐mutually exclusive theories, the maternal immune activatio...... hiện toàn bộ
Behavioral profiling of multiple pairs of rats selectively bred for high and low alcohol intake using the MCSF test
Addiction Biology - Tập 17 Số 1 - Trang 33-46 - 2012
Erika Roman, Robert B. Stewart, Megan L. Bertholomey, Meredith L. Jensen, Giancarlo Colombo, Petri Hyytiä, Nancy E. Badia‐Elder, Nicholas J. Grahame, Ting‐Kai Li, Lawrence Lumeng
ABSTRACTGenetic aspects of alcoholism have been modeled using rats selectively bred for extremes of alcohol preference and voluntary alcohol intake. These lines show similar alcohol drinking phenotypes but have different genetic and environmental backgrounds and may therefore display diverse behavioral traits as seen in human alcoholics. The multivariate concentric...... hiện toàn bộ
REVIEW: The UChA and UChB rat lines: metabolic and genetic differences influencing ethanol intake
Addiction Biology - Tập 11 Số 3-4 - Trang 310-323 - 2006
Marı́a Elena Quintanilla, Yedy Israel, Amalia Sapag, Lutske Tampier
ABSTRACTEthanol non‐drinker (UChA) and drinker (UChB) rat lines derived from an original Wistar colony have been selectively bred at the University of Chile for over 70 generations. Two main differences between these lines are clear. (1) Drinker rats display a markedly faster acute tolerance than non‐drinker rats. In F2... hiện toàn bộ
Neural network activation during a stop‐signal task discriminates cocaine‐dependent from non‐drug‐abusing men
Addiction Biology - Tập 19 Số 3 - Trang 427-438 - 2014
Amanda Elton, J. A. Young, Sonet Smitherman, Robin Gross, Tanja Mletzko, Clinton D. Kilts
AbstractCocaine dependence is defined by a loss of inhibitory control over drug‐use behaviors, mirrored by measurable impairments in laboratory tasks of inhibitory control. The current study tested the hypothesis that deficits in multiple subprocesses of behavioral control are associated with reliable neural‐processing alterations that define cocaine addiction. Whi...... hiện toàn bộ
Puberty as a highly vulnerable developmental period for the consequences of cannabis exposure
Addiction Biology - Tập 13 Số 2 - Trang 253-263 - 2008
Miriam Schneider
ABSTRACTDuring puberty, neuronal maturation of the brain, which began during perinatal development, is completed such that the behavioral potential of the adult organism can be fully achieved. These maturational events and processes of reorganization are needed for the occurrence of adult behavioral performance but simultaneously render the organism highly suscepti...... hiện toàn bộ
IMAGING STUDY: Prefrontal cortex morphometry in abstinent adolescent marijuana users: subtle gender effects
Addiction Biology - Tập 14 Số 4 - Trang 457-468 - 2009
Krista M. Lisdahl, Tim McQueeny, Bonnie J. Nagel, Karen L. Hanson, Tony T. Yang, Susan F. Tapert
ABSTRACTAdult human studies suggest frontal dysfunction associated with chronic marijuana (MJ) use, but due to continued neuromaturation, adult studies may not generalize to adolescents. This study characterized prefrontal cortex (PFC) morphometry in chronic MJ‐using adolescents following 1 month of monitored abstinence. Data were collected from MJ users (... hiện toàn bộ
Greater externalizing personality traits predict less error‐related insula and anterior cingulate cortex activity in acutely abstinent cigarette smokers
Addiction Biology - Tập 20 Số 2 - Trang 377-389 - 2015
Allison J. Carroll, Matthew T. Sutherland, Betty Jo Salmeron, Thomas J. Ross, Elliot A. Stein
AbstractAttenuated activity in performance‐monitoring brain regions following erroneous actions may contribute to the repetition of maladaptive behaviors such as continued drug use. Externalizing is a broad personality construct characterized by deficient impulse control, vulnerability to addiction and reduced neurobiological indices of error processing. The insula...... hiện toàn bộ
Involvement of the corticostriatal glutamatergic pathway in ethanol‐induced ascorbic acid release in rat striatum
Addiction Biology - Tập 4 Số 3 - Trang 273-281 - 1999
Jing Liu, Chunfu Wu, Liu Wen, Hong‐Ling Zhang, Chun‐Li Li
AbstractThe mechanism of ethanol‐induced ascorbic acid (AA) release in striatum is not well understood. In the present work, the possible involvement of NMDA receptors in the corticostriatal pathway was studied by microdialysis coupled to high performance liquid chromatography with electrochemical detection. Ethanol (3.0 g/kg i.p.) stimulated significant striatal A...... hiện toàn bộ
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