Addiction Biology
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Greater externalizing personality traits predict less error‐related insula and anterior cingulate cortex activity in acutely abstinent cigarette smokersAbstract Attenuated activity in performance‐monitoring brain regions following erroneous actions may contribute to the repetition of maladaptive behaviors such as continued drug use. Externalizing is a broad personality construct characterized by deficient impulse control, vulnerability to addiction and reduced neurobiological indices of error processing. The insula... ... hiện toàn bộ
Addiction Biology - Tập 20 Số 2 - Trang 377-389 - 2015
Age‐related differences in working memory deficits during nicotine withdrawalAbstract Nicotine withdrawal is associated with subtle working memory deficits that predict subsequent relapse. We examined the neural substrates underlying these processes in treatment‐seeking smokers, and explored the moderating influence of age on abstinence‐induced alterations in brain activity and performance. Sixty‐three smokers participated in two blood oxyge... ... hiện toàn bộ
Addiction Biology - Tập 19 Số 5 - Trang 907-917 - 2014
Gender differences in the pharmacology of nicotine addictionAbstract Smoking rates have declined in recent years less rapidly in women than in men. More adolescent girls than boys are currently smoking. Quitting smoking is reported in many studies to be more difficult in women than in men. These observations suggest that there may be gender differences in the nature of nicotine addiction. Gender differences in various pharma... ... hiện toàn bộ
Addiction Biology - Tập 3 Số 4 - Trang 383-404 - 1998
Involvement of the corticostriatal glutamatergic pathway in ethanol‐induced ascorbic acid release in rat striatumAbstract The mechanism of ethanol‐induced ascorbic acid (AA) release in striatum is not well understood. In the present work, the possible involvement of NMDA receptors in the corticostriatal pathway was studied by microdialysis coupled to high performance liquid chromatography with electrochemical detection. Ethanol (3.0 g/kg i.p.) stimulated significant striatal A... ... hiện toàn bộ
Addiction Biology - Tập 4 Số 3 - Trang 273-281 - 1999
Ethanol metabolism in the brainAbstract Acetaldehyde is suspected of being involved in the central mechanism of central nervous system depression and addiction to ethanol, but in contrast to ethanol, it can not penetrate easily from blood into the brain because of metabolic barriers. Therefore, the possibility of ethanol metabolism and acetaldehyde formation inside the brain has been one of the c... ... hiện toàn bộ
Addiction Biology - Tập 2 Số 4 - Trang 387-400 - 1997
Behavioral effects of four novel synthetic cathinone analogs in rodentsAbstract A new generation of novel cathinone compounds has been developed as stimulant substitutes to avoid drug control laws and detection of use by blood tests. Dipentylone, N ‐ethylhexedrone, 4‐chloroethcathinone (4‐CEC), and 4′‐methyl‐α‐pyrrolidinohexiophenone (MPHP) were tested for in vivo psychostimulant‐like effects to assess their a... ... hiện toàn bộ
Addiction Biology - Tập 26 Số 4 - 2021
The effect of tobacco smoking on subjective symptoms of inadequacy (“not holding”) of methadone dose among opiate addicts in methadone maintenance treatmentAbstract The objective of this study was to examine the relationship between subjective symptoms of inadequacy of methadone dose (not feeling “held”) and tobacco smoking in patients in methadone maintenance treatment (MMT). This was a cross‐sectional study of smoking behaviour, investigating subjective, physiological and psychological symptoms. The study took place ... ... hiện toàn bộ
Addiction Biology - Tập 6 Số 2 - Trang 137-145 - 2001
Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats
Addiction Biology - Tập 18 Số 5 - Trang 786-799 - 2013
Identifying the neural circuitry of alcohol craving and relapse vulnerabilityABSTRACT With no further intervention, relapse rates in detoxified alcoholics are high and usually exceed 80% of all detoxified patients. It has been suggested that stress and exposure to priming doses of alcohol and to alcohol‐associated stimuli (cues) contribute to the relapse risk after detoxification. This article focuses on neuronal correlates of cue responses ... ... hiện toàn bộ
Addiction Biology - Tập 14 Số 1 - Trang 108-118 - 2009
Cocaine use severity and cerebellar gray matter are associated with reversal learning deficits in cocaine-dependent individuals
Addiction Biology - Tập 20 Số 3 - Trang 546-556 - 2015
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