APMIS
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Role of interferons and other cytokines in the regulation of the immune response
APMIS - Tập 103 Số 1-6 - Trang 161-179 - 1995
Cytokines represent the major factors involved in the communication between T
cells, macrophages and other immune cells in the course of an immune response to
antigens and infectious agents. A number of studies on mouse and human T helper
(Th) clones have recently provided extensive evidence for the existence of
different activities exhibited by Th cells (called Th1 and Th2), which was
apparently ...
THE IMPACT ON THE DEVELOPING EMBRYO AND NEWBORN ANIMAL OF ADULT HOMOLOGOUS CELLS
APMIS - Tập 40 Số 6 - Trang 480-500 - 1957
erm genes in erythromycin‐resistant Staphylococcus aureus and coagulase‐negative staphylococci
APMIS - Tập 103 Số 1-6 - Trang 225-232 - 1995
Erythromycin‐resistant S. aureus from general practice and a dermatology ward
with a very high consumption of erythromycin was studied for ermA and ermC
content by Southern blot analysis. The prevalence of these erm genes was also
studied in coagulase‐negative staphylococci from the same dermatology ward and
in a collection of 15 S. aureus and 18 coagulase‐negative staphylococci found in
the same ...
A histomorphometric determination of iliac bone remodeling in patients with recurrent renal stone formation and idiopathic hypercalciuria
APMIS - Tập 97 Số 1-6 - Trang 309-316 - 1989
33 normocalcemic patients (22 males and 11 females) aged 20–68 years with
recurrent renal stone formation and idiopathic hypercalciuria were compared to
33 approximately sex‐ and age‐matched normal controls. Quantitative
histomorphometric analysis of iliac crest biopsies were performed after
intravital tetracycline double labeling in the patients and in 30 sex‐ and
age‐matched normal controls. No ...
Lactoferrin: A multifunctional glycoprotein
APMIS - Tập 107 Số 7-12 - Trang 971-981 - 1999
Lactoferrin is an iron‐binding glycoprotein found in milk, exocrine secretions
of mammals, and in secondary granules from polymorphonuclear neutrophils. This
review describes the wide spectrum of functions ascribed to lactoferrin, with
special emphasis on the antimicrobial properties of this protein, and its
derived peptides.
Biological significance of IgA1 proteases in bacterial colonization and pathogenesis: critical evaluation of experimental evidence
APMIS - Tập 104 Số 1-6 - Trang 321-338 - 1996
Endogenous angiogenesis inhibitors
APMIS - Tập 112 Số 7-8 - Trang 496-507 - 2004
When the FDA commissioner announced in February 2004 the approval of Avastin for
the treatment of patients with colon cancer, he called angiogenesis inhibitors a
fourth modality of anti‐cancer therapy. Because angiogenesis inhibitors are
relatively less toxic than conventional chemotherapy and have a lower risk of
drug resistance, they may also represent a new class of anti‐cancer agents, some
of ...
The Legionella micdadei flagellin: Expression in Escherichia coli K 12 and DNA sequence of the gene
APMIS - Tập 103 Số 7-8 - Trang 869-877 - 1995
To study the structure and function of the Legionella flagellum, we screened a
genomic L. micdadei library in Escherichia coli for expression of the flagellin
(Fla) subunit. One recombinant clone, JM105 (pHI5588), producing a truncated Fla
protein of 40.5 kDa was identified. The plasmid pHI5588 carried a L. micdadei
DNA insert of 5 kb, containing ca 95% of the fla gene. The complete DNA sequence
o...
Pathophysiological effects of human TNF‐alpha‐producing tumor xenografts in immunosuppressed mice
APMIS - Tập 107 Số 7-12 - Trang 903-912 - 1999
Groups of CBA mice immunosuppressed with antithymocyte serum (ATS) treatment
were xeno‐transplanted with either HeLa human cervical carcinoma cells or
genetically modified cells expressing the human tumor necrosis factor‐α (TNF)
gene (All cells). Both cell lines were highly resistant to the cytotoxic effects
of TNF. If 3 times 106 tumor cells were inoculated s.c. into female mice, HeLa
cells grew ...
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