APMIS
SCOPUS (1988-2025)SCIE-ISI
0903-4641
1600-0463
Đan mạch
Cơ quản chủ quản: WILEY , Blackwell Munksgaard
Lĩnh vực:
Microbiology (medical)Immunology and AllergyMedicine (miscellaneous)Pathology and Forensic Medicine
Các bài báo tiêu biểu
The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis
Tập 96 Số 7-12 - Trang 857-881 - 1988
The new stereological methods for correct and efficient sampling and sizing of
cells and other particles are reviewed. There is a hierarchy of methods starting
from the simplest where even the microscopic magnification may be unknown to the
most complex where typically both section thickness and the magnification must
be known. Opticalsections in suitably modified microscopes can be used to
improv...
Quantification of biofilm in microtiter plates: overview of testing conditions and practical recommendations for assessment of biofilm production by staphylococci
Tập 115 Số 8 - Trang 891-899 - 2007
The details of all steps involved in the quantification of biofilm formation in
microtiter plates are described. The presented protocol incorporates information
on assessment of biofilm production by staphylococci, gained both by direct
experience as well as by analysis of methods for assaying biofilm production.
The obtained results should simplify quantification of biofilm formation in
microtite...
The role of bacterial biofilms in chronic infections
Tập 121 Số s136 - Trang 1-58 - 2013
Acute infections caused by pathogenic bacteria have been studied extensively for
well over 100 years. These infections killed millions of people in previous
centuries, but they have been combated effectively by the development of modern
vaccines, antibiotics and infection control measures. Most research into
bacterial pathogenesis has focused on acute infections, but these diseases have
now been s...
Role of interferons and other cytokines in the regulation of the immune response
Tập 103 Số 1-6 - Trang 161-179 - 1995
Cytokines represent the major factors involved in the communication between T
cells, macrophages and other immune cells in the course of an immune response to
antigens and infectious agents. A number of studies on mouse and human T helper
(Th) clones have recently provided extensive evidence for the existence of
different activities exhibited by Th cells (called Th1 and Th2), which was
apparently ...
Lipofuscin: Mechanisms of formation and increase with age
Tập 106 Số 1-6 - Trang 265-276 - 1998
Lipofuscin (age pigment) is a brown‐yellow, electron‐dense, autofluorescent
material that accumulates progressively over time in lysosomes of postmitotic
cells, such as neurons and cardiac myocytes. The exact mechanisms behind this
accumulation are still unclear. This review outlines the present knowledge of
age pigment formation, and considers possible mechanisms responsible for the
increase of l...
Endogenous angiogenesis inhibitors
Tập 112 Số 7-8 - Trang 496-507 - 2004
When the FDA commissioner announced in February 2004 the approval of Avastin for
the treatment of patients with colon cancer, he called angiogenesis inhibitors a
fourth modality of anti‐cancer therapy. Because angiogenesis inhibitors are
relatively less toxic than conventional chemotherapy and have a lower risk of
drug resistance, they may also represent a new class of anti‐cancer agents, some
of ...
Dental biofilm infections – an update
Tập 125 Số 4 - Trang 376-384 - 2017
Teeth are colonized by oral bacteria from saliva containing more than 700
different bacterial species. If removed regularly, the dental biofilm mainly
comprises oral streptococci and is regarded as resident microflora. But if left
undisturbed, a complex biofilm containing up to 100 bacterial species at a site
will build up and may eventually cause development of disease. Depending on
local ecologi...
Biological significance of IgA1 proteases in bacterial colonization and pathogenesis: critical evaluation of experimental evidence
Tập 104 Số 1-6 - Trang 321-338 - 1996
Lactoferrin: A multifunctional glycoprotein
Tập 107 Số 7-12 - Trang 971-981 - 1999
Lactoferrin is an iron‐binding glycoprotein found in milk, exocrine secretions
of mammals, and in secondary granules from polymorphonuclear neutrophils. This
review describes the wide spectrum of functions ascribed to lactoferrin, with
special emphasis on the antimicrobial properties of this protein, and its
derived peptides.
THE IMPACT ON THE DEVELOPING EMBRYO AND NEWBORN ANIMAL OF ADULT HOMOLOGOUS CELLS
Tập 40 Số 6 - Trang 480-500 - 1957