APMIS

SCOPUS (1988-2023)SCIE-ISI

  0903-4641

  1600-0463

  Đan mạch

Cơ quản chủ quản:  WILEY , Blackwell Munksgaard

Lĩnh vực:
Microbiology (medical)Immunology and AllergyMedicine (miscellaneous)Pathology and Forensic Medicine

Các bài báo tiêu biểu

The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis
Tập 96 Số 7-12 - Trang 857-881 - 1988
H.J.G. Gundersen, Peter V. Bagger, Thomas Fichtner Bendtsen, Stephen M. Evans, Lise Korbo, Niels Marcussen, Arne Moeller, K Nielsen, J. R. Nyengaard, Bente Pakkenberg, Flemming Brandt Sørensen, A. Vesterby, Mark J. West
The new stereological methods for correct and efficient sampling and sizing of cells and other particles are reviewed. There is a hierarchy of methods starting from the simplest where even the microscopic magnification may be unknown to the most complex where typically both section thickness and the magnification must be known. Opticalsections in suitably modifie...... hiện toàn bộ
Quantification of biofilm in microtiter plates: overview of testing conditions and practical recommendations for assessment of biofilm production by staphylococci
Tập 115 Số 8 - Trang 891-899 - 2007
Srdjan Stepanović, Dragana Vuković, Veronika Holá, Giovanni Di Bonaventura, Slobodanka Djukić, Ivana Ćirković, Filip Růžička
The details of all steps involved in the quantification of biofilm formation in microtiter plates are described. The presented protocol incorporates information on assessment of biofilm production by staphylococci, gained both by direct experience as well as by analysis of methods for assaying biofilm production. The obtained results should simplify quantification of biofilm formation in m...... hiện toàn bộ
The role of bacterial biofilms in chronic infections
Tập 121 Số s136 - Trang 1-58 - 2013
Thomas Bjarnsholt
Acute infections caused by pathogenic bacteria have been studied extensively for well over 100 years. These infections killed millions of people in previous centuries, but they have been combated effectively by the development of modern vaccines, antibiotics and infection control measures. Most research into bacterial pathogenesis has focused on acute infections, but these diseases have no...... hiện toàn bộ
Role of interferons and other cytokines in the regulation of the immune response
Tập 103 Số 1-6 - Trang 161-179 - 1995
Filippo Belardelli
Cytokines represent the major factors involved in the communication between T cells, macrophages and other immune cells in the course of an immune response to antigens and infectious agents. A number of studies on mouse and human T helper (Th) clones have recently provided extensive evidence for the existence of different activities exhibited by Th cells (called Th1 and Th2), which was app...... hiện toàn bộ
Lipofuscin: Mechanisms of formation and increase with age
Tập 106 Số 1-6 - Trang 265-276 - 1998
Alexei Terman, Ulf Brunk
Lipofuscin (age pigment) is a brown‐yellow, electron‐dense, autofluorescent material that accumulates progressively over time in lysosomes of postmitotic cells, such as neurons and cardiac myocytes. The exact mechanisms behind this accumulation are still unclear. This review outlines the present knowledge of age pigment formation, and considers possible mechanisms responsible for the incre...... hiện toàn bộ
Endogenous angiogenesis inhibitors
Tập 112 Số 7-8 - Trang 496-507 - 2004
Judah Folkman
When the FDA commissioner announced in February 2004 the approval of Avastin for the treatment of patients with colon cancer, he called angiogenesis inhibitors a fourth modality of anti‐cancer therapy. Because angiogenesis inhibitors are relatively less toxic than conventional chemotherapy and have a lower risk of drug resistance, they may also represent a new class of anti‐cancer agents, ...... hiện toàn bộ
Dental biofilm infections – an update
Tập 125 Số 4 - Trang 376-384 - 2017
Tove Larsen, Nils‐Erik Fiehn
Teeth are colonized by oral bacteria from saliva containing more than 700 different bacterial species. If removed regularly, the dental biofilm mainly comprises oral streptococci and is regarded as resident microflora. But if left undisturbed, a complex biofilm containing up to 100 bacterial species at a site will build up and may eventually cause development of disease. Depending on local...... hiện toàn bộ
Biological significance of IgA1 proteases in bacterial colonization and pathogenesis: critical evaluation of experimental evidence
Tập 104 Số 1-6 - Trang 321-338 - 1996
Mogens Kilian, Jesper Reinholdt, Hans B. Lomholt, Keith P. Poulsen, E V Frandsen
Lactoferrin: A multifunctional glycoprotein
Tập 107 Số 7-12 - Trang 971-981 - 1999
Lars H. Vorland
Lactoferrin is an iron‐binding glycoprotein found in milk, exocrine secretions of mammals, and in secondary granules from polymorphonuclear neutrophils. This review describes the wide spectrum of functions ascribed to lactoferrin, with special emphasis on the antimicrobial properties of this protein, and its derived peptides.
THE IMPACT ON THE DEVELOPING EMBRYO AND NEWBORN ANIMAL OF ADULT HOMOLOGOUS CELLS
Tập 40 Số 6 - Trang 480-500 - 1957
Morten Simonsen