Dual release behavior of atorvastatin and alpha-lipoic acid from PLGA microspheres for the combination therapy in peripheral nerve injury

Journal of Drug Delivery Science and Technology - Tập 39 - Trang 455-466 - 2017
Hakan Eroğlu1, Mohammad Karim Haidar1, Emirhan Nemutlu2, Şükrü Öztürk3, Cem Bayram4, Kezban Ulubayram3,5, Levent Öner1
1Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Technology, 06100 Sıhhiye, Ankara, Turkey
2Hacettepe University, Faculty of Pharmacy, Department of Analytical Chemistry, 06100 Sıhhıye, Ankara, Turkey
3Hacettepe University, Institute for Graduate Studies in Science and Engineering, Bioengineering Division, 06100, Beytepe, Ankara, Turkey
4Hacettepe University, Advanced Technologies Application and Research Center, 06800, Beytepe, Ankara, Turkey
5Hacettepe University, Faculty of Pharmacy, Department of Basic Pharmaceutical Sciences, 06100 Sıhhıye, Ankara, Turkey

Tài liệu tham khảo

Childs, 2003, Double crush syndrome, Orthop. Nurs., 22, 117, 10.1097/00006416-200303000-00008

Grace, 1994, Ischaemia-reperfusion injury, Br. J. Surg., 81, 637, 10.1002/bjs.1800810504

Griffin, 2014, Peripheral nerve injury: principles for repair and regeneration, Open Orthop. J., 8, 199, 10.2174/1874325001408010199

Johnson, 2010, Controlled release of neurotrophin-3 and platelet-derived growth factor from fibrin scaffolds containing neural progenitor cells enhances survival and differentiation into neurons in a subacute model of SCI, Cell Transpl., 19, 89, 10.3727/096368909X477273

Wilems, 2015, Sustained dual drug delivery of anti-inhibitory molecules for treatment of spinal cord injury, J. Control Release, 213, 103, 10.1016/j.jconrel.2015.06.031

Reed, 1951, Crystalline alpha-lipoic acid; a catalytic agent associated with pyruvate dehydrogenase, Science, 114, 93, 10.1126/science.114.2952.93

Pick, 1995, Glutathione reductase and lipoamide dehydrogenase have opposite stereospecificities for alpha-lipoic acid enantiomers, Biochem. Biophys. Res. Commun., 206, 724, 10.1006/bbrc.1995.1102

Packer, 1997, Neuroprotection by the metabolic antioxidant alpha-lipoic acid, Free Radic. Biol. Med., 22, 359, 10.1016/S0891-5849(96)00269-9

Packer, 1995, alpha-Lipoic acid as a biological antioxidant, Free Radic. Biol. Med., 19, 227, 10.1016/0891-5849(95)00017-R

Whiteman, 1996, Protection against peroxynitrite-dependent tyrosine nitration and alpha 1-antiproteinase inactivation by ascorbic acid. A comparison with other biological antioxidants, Free Radic. Res., 25, 275, 10.3109/10715769609149052

Laufs, 2000, Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice, Stroke, 31, 2442, 10.1161/01.STR.31.10.2442

Lu, 2004, Atorvastatin reduces neurological deficit and increases synaptogenesis, angiogenesis, and neuronal survival in rats subjected to traumatic brain injury, J. Neurotrauma, 21, 21, 10.1089/089771504772695913

Youssef, 2002, The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease, Nature, 420, 78, 10.1038/nature01158

Gao, 2016, Atorvastatin activates autophagy and promotes neurological function recovery after spinal cord injury, Neural Regen. Res., 11, 977, 10.4103/1673-5374.184498

Vaughan, 1999, Neuroprotective properties of statins in cerebral ischemia and stroke, Stroke, 30, 1969, 10.1161/01.STR.30.9.1969

Rivera, 2004, Fluconazole encapsulation in PLGA microspheres by spray-drying, J. Microencapsul., 21, 203, 10.1080/02652040310001637811

Arıca, 1993, Microencapsulation of diclofenac sodium by spray drying process, 24

Eroglu, 2015, Evaluation of characteristics and in vitro antioxidant properties of RSV loaded hyaluronic acid-DPPC microparticles as a wound healing system, Colloids Surf. B Biointerfaces, 126, 50, 10.1016/j.colsurfb.2014.12.006

European Medicines Agency, ICH Topic Q2 (R1) Validation of Analytical Procedures: Text and Methodology, http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/WC500002662.pdf, 1995, 05.01.2017.

Bodmeier, 1988, Solvent selection in the preparation of poly(Dl-Lactide) microspheres prepared by the solvent evaporation method, Int. J. Pharm., 43, 179, 10.1016/0378-5173(88)90073-7

Carvalho, 2012, Characterization of atorvastatin by TG and DSC, Braz. J. Therm. Analysis, 1, 79

Oliveira, 2013, Degradation kinetics of atorvastatin under stress conditions and chemical analysis by HPLC, Molecules, 18, 1447, 10.3390/molecules18021447

PubChem. Open Chemistry Database dl-Thioctic acid. 2017 19.04.2017]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/dl-Thioctic_acid-section=Top.