Fluoxetine reduces explosiveness and elevates mood of Vietnam combat vets with PTSD

Journal of Traumatic Stress - Tập 5 - Trang 97-101 - 1992
Jonathan Shay1
1Department of Psychiatry, Tufts Medical School and Boston D.V.A. Outpatient Clinic, Boston

Tóm tắt

Thirteen of 18 depressed Vietnam War combat veterans who had frequent, explosive outbursts of rage enjoyed reduced explosiveness when treated with fluoxetine, They displayed and reported a greater ability to think rather than act. Duration of anger also diminished; and mood improved.

Tài liệu tham khảo

Coccaro, E. F., Astill, J. L., Herbert, J. L., and Schut, A. G. (1990). Fluoxetine treatment of impulsive aggression in DSM-III-R personality disorder patients.J. Clin. Psychopharmacol. 10: 373–375.

Coccaro, E. F.,et al. (1989). Serotonergic studies in patients with affective and personality disorders.Arch. Gen. Psychiatry 46: 587–599.

Cowdry, R. W., and Gardner, D. L. (1988). Pharmacotherapy of borderline personality disorder.Arch. Gen. Psychiatry 45: 11–119.

Homer. (1974).The Iliad (R. Fitzgerald Trans.), Anchor/Doubleday, New York: (Original composed ca. 2,800 BCE), Book 18 Line 116.

Kulka, R. A., Schlenger, W. E., Fairbank, J. A., Hough, R. L., Jordan, B. K., Marmar, C. R., and Weiss, D. S. (1990).The National Vietnam Veterans Readjustment Study: Tables of Findings and Technical Appendices Brunner/Mazel, New York.

Munroe, J., Fisher, L., Shay, J., Wattenberg, M., Makary, C., Keefe, E., Cook, J., and Rapperport, K. (1990). Trust and team techniques in treating Vietnam combat veterans. 6th Annual Meeting of the Society of Traumatic Stress Studies, New Orleans, LA.

Ross, R. J., Ball, W. A., and Sullivan, K. A.,et al. (1989). Sleep disturbance as the hallmark of post-traumatic stress disorder.Am. J. Psychiat. 146: 697–707.

Shay, J. (1989). Fluoxetine reduces explosiveness and elevates mood of Vietnam combat vets with PTSD. 5th Annual Meeting of the Society for Traumatic Stress Studies, San Francisco, CA.

Tupin, J. P.,et al. (1973). The long-term use of lithium in aggressive prisoners.Comp. Psychiatry 14: 311–317.

van der Kolk, B. A. (1988). The trauma spectrum: The interaction of biological and social events in the genesis of the trauma response.J. Traum. Stress 1: 273–290.

Virkkunen, M., DeJong, J., Bartko, J., and Linnoila, M. (1989). Psychobiological concomitants of history of suicide attempts among violent offenders and impulsive fire setters.Arch. Gen. Psychiatry 46: 604–606.

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Thông tin xuất bản

Journal of Traumatic Stress

Tập 5

97-101

Thông tin tác giả