Widespread Fosfomycin Resistance in Gram-Negative Bacteria Attributable to the Chromosomal fosA GenemBio - Tập 8 Số 4 - 2017
Ryota Ito, Mustapha M. Mustapha, Adam D. Tomich, Jake D. Callaghan, Christi L. McElheny, Roberta T. Mettus, Robert M. Q. Shanks, Nicolas Sluis‐Cremer, Yohei Doi
ABSTRACT
Fosfomycin is a decades-old antibiotic which is being revisited because of its perceived activity against many extensively drug-resistant Gram-negative pathogens. FosA proteins are Mn
2+
and K
+
-dependent glutathione
S<...... hiện toàn bộ
Cell Wall Remodeling Enzymes Modulate Fungal Cell Wall Elasticity and Osmotic Stress ResistancemBio - Tập 6 Số 4 - 2015
Iuliana V. Ene, Louise A. Walker, Marion Schiavone, Keunsook K. Lee, Hélène Martin‐Yken, Étienne Dague, Neil A. R. Gow, Carol A. Munro, Alistair J. P. Brown
ABSTRACT
The fungal cell wall confers cell morphology and protection against environmental insults. For fungal pathogens, the cell wall is a key immunological modulator and an ideal therapeutic target. Yeast cell walls possess an inner matrix of interlinked β-glucan and chitin that is thought to provide tensile strength and rigidity. Yeast ce...... hiện toàn bộ
Bactofencin A, a New Type of Cationic Bacteriocin with Unusual ImmunitymBio - Tập 4 Số 6 - 2013
Eileen F. O'Shea, Paula M. O’Connor, Órla O’Sullivan, Paul D. Cotter, R. Paul Ross, Colin Hill
ABSTRACT
Bacteriocin production is an important probiotic trait of intestinal bacteria. In this study, we identify a new type of bacteriocin, bactofencin A, produced by a porcine intestinal isolate
Lactobacillus salivarius
DPC6502, and assess its pot...... hiện toàn bộ
Drivers of Microbiome Biodiversity: A Review of General Rules, Feces, and IgnorancemBio - Tập 9 Số 4 - 2018
Aspen T. Reese, Robert R. Dunn
The alpha diversity of ecologic communities is affected by many biotic and abiotic drivers and, in turn, affects ecosystem functioning. Yet, patterns of alpha diversity in host-associated microbial communities (microbiomes) are poorly studied and the appropriateness of general theory is untested.
Extracellular Enzymes Facilitate Electron Uptake in Biocorrosion and BioelectrosynthesismBio - Tập 6 Số 2 - 2015
Jörg S. Deutzmann, Merve Şahin, Alfred M. Spormann
ABSTRACT
Direct, mediator-free transfer of electrons between a microbial cell and a solid phase in its surrounding environment has been suggested to be a widespread and ecologically significant process. The high rates of microbial electron uptake observed during microbially influenced corrosion of iron [Fe(0)] and during microbial electrosynt...... hiện toàn bộ
Escherichia coli ST131- H 22 as a Foodborne UropathogenmBio - Tập 9 Số 4 - 2018
Cindy M. Liu, Marc Stegger, Maliha Aziz, Timothy J. Johnson, Kara Waits, Lora Nordstrom, Lori Gauld, Brett Weaver, Diana Rolland, Sally Statham, Joseph Horwinski, Sanjeev Sariya, Gregg S. Davis, Evgeni V. Sokurenko, Paul Keim, James R. Johnson, Lance B. Price
E. coli
ST131 is an important extraintestinal pathogen that can colonize the gastrointestinal tracts of humans and food animals. Here, we combined detection of accessory traits associated with avian adaptation (ColV plasmids) with high-resolution phylogenetics to quantify the portion of human inf...... hiện toàn bộ