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Connectomics: novel methods for the dense reconstruction of neuronal circuits
e-Neuroforum - Tập 4 - Trang 18-21 - 2013
M. Helmstaedter
The nervous system is characterized by extremely complex cell-to-cell interactions which primarily occur via chemical synapses. Mapping the structure of these intercellular networks is one of the major challenges in neuroscience. The new field of connectomics which has developed in recent years aims at the dense reconstruction of increasingly comprehensive nerve cell networks. Automated volume ele... hiện toàn bộ
Hereditary hearing loss in humans: the importance of genetic approaches for clinical medicine and basic science
e-Neuroforum - Tập 5 - Trang 67-71 - 2014
C. Kubisch
Hereditary hearing loss is one of the most common monogenic diseases in humans and, depending on the severity of symptoms and age of onset, dysfunction of one of the main sensory systems can cause significant problems for the affected individual and his/her social environment. The diagnostic workup of hearing impairment is complicated by a pronounced phenotypic variability and extensive genetic he... hiện toàn bộ
Giant synapses in the central auditory system
e-Neuroforum - Tập 5 - Trang 53-59 - 2014
F. Felmy, T. Künzel
Giant synapses occur in four nuclei of the auditory brainstem. They are characterized by numerous active zones concentrated on the soma of the postsynaptic neuron and by rapid postsynaptic currents. At these sites, in the ventral cochlear nucleus, the medial and lateral nucleus of the trapezoid body and the ventral nucleus of the lateral lemniscus, faithful preservation of the temporal relation of... hiện toàn bộ
Computation of motion direction in the vertebrate retina
e-Neuroforum - Tập 18 Số 3 - Trang 49-58 - 2012
Thomas Euler, Susanne Hausselt
Abstract How direction of image motion is detected as early as at the level of the vertebrate eye has been intensively studied in retina research. Although the first direction-selective (DS) ret­inal ganglion cells were already described in the 1960s and have since then been in the fo­cus of many studies, scientists are still puz­zled by the intricacy of the neuronal circuits and computational mec... hiện toàn bộ
ADAM10: α-secretase in Alzheimer’s disease and regulator of neurobiology
e-Neuroforum - Tập 5 - Trang 37-42 - 2014
P. Saftig, J. Prox
Proteolytic and amyloidogenic processing of amyloid precursor protein (APP) by β- and γ-secretases are pathological hallmarks of Alzheimer’s disease (AD). These proteolytic activities lead to release of the amyloid-β peptides believed to cause neurological pathology and be linked to pathological progression in AD. Due to its capability to cleave APP within the toxic peptide sequence, the metallopr... hiện toàn bộ
Neuronal pathways of embarrassment
e-Neuroforum - Tập 7 - Trang 37-42 - 2016
Sören Krach, Laura Müller-Pinzler, Lena Rademacher, David Sören Stolz, Frieder Michel Paulus
Embarrassment is a genuine human emotion that we experience while being publicly exposed in unfavorable situations. The embarrassment we feel informs us how we perform according to prevalent norms and moral values and helps to regulate the impression we make on others. One cornerstone of embarrassment is the capacity to take another’s perspective and reflect on the thoughts, feelings, and intentio... hiện toàn bộ
Vai trò của não trong béo phì ở người Dịch bởi AI
e-Neuroforum - Tập 4 - Trang 79-84 - 2013
A. Horstmann, A. Villringer
Nguyên nhân phổ biến nhất gây béo phì là sự mất cân bằng năng lượng dương, tức là năng lượng tiêu thụ nhiều hơn năng lượng tiêu hao. Sự gia tăng tỷ lệ béo phì không thể được giải thích chỉ dựa trên môi trường tạo điều kiện cho béo phì, vì tồn tại sự khác biệt lớn về tình trạng cân nặng giữa các cá nhân. Do đó, nguyên nhân có khả năng cao là do sự tương tác giữa hành vi cá nhân và môi trường đã tha... hiện toàn bộ
#béo phì #năng lượng #cấu trúc não #hành vi ăn uống #khoa học thần kinh
Neurobiological research in psychiatry—classification of dimensions of learning mechanisms instead of reification of categories?
e-Neuroforum - Tập 17 Số 4 - Trang 88-94 - 2011
Andreas Heinz, Anne Beck
Abstract Neuroscientific research in mental disorders is plagued by unclear nosological boundaries, phenotypic diversity, and high intra- and interindividual variability of identified neurobi­ological correlates. Likewise, genotypes asso­ciated with an increased risk for, e.g., schizophrenia are regularly found to also increase the risk for uni- and/or bipolar affective dis­orders. Therefore, one ... hiện toàn bộ
Connectomics: a need for comparative studies
e-Neuroforum - - 2016
Gilles Laurent
Erratum to: Learning from brain control: clinical application of brain–computer interfaces
e-Neuroforum - Tập 6 - Trang 113-113 - 2015
Niels Birbaumer, Ujwal Chaudhary
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