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Các bài báo tiêu biểu
Context conditioning in virtual reality as a model for pathological anxietyAbstract
Phobic fear which is triggered by specific stimuli can be modeled experimentally through cue conditioning. In contrast, context conditioning may serve as a model for anxiety which is longer lasting and unrelated to cues. Such context conditioning can be studied in humans in analogy to animal studies by using virtual reality (VR). Our VR... ...
Tập 19 Số 3 - Trang 63-70 - 2013
Neuronal circuits of fear memory and fear extinctionAbstract
The paradigm“eat or be eaten” has proven to be a critical guiding element during the evolution of both humans and animals. This helps to explain the fact that the ability to detect danger or a threat has been highly conserved throughout evolution and thus exhibits a high degree of homology between species. Studies in laboratory animals ... ...
- 2013
Pain processing in multisensory environmentsAbstract
“Don’t look and it won’t hurt” is common advice heard before receiving an injection, but is there any truth in this statement? Pain processing can be separated into two major components: a sensory-discriminative component, which reflects the location and intensity of a painful event, and an affective-motivational component that reflect... ...
Tập 16 Số 2 - Trang 23-28 - 2010
Neurobiological research in psychiatry—classification of dimensions of learning mechanisms instead of reification of categories?Abstract
Neuroscientific research in mental disorders is plagued by unclear nosological boundaries, phenotypic diversity, and high intra- and interindividual variability of identified neurobiological correlates. Likewise, genotypes associated with an increased risk for, e.g., schizophrenia are regularly found to also increase the risk for uni- and/... ...
Tập 17 Số 4 - Trang 88-94 - 2011
Sniffing out social signalsAbstract
In most mammals, conspecific chemical communication strategies control complex social and sexual behavior. Just a few years ago, our concept of how the olfactory system is organized to ensure faithful transmission of social information built on the rather simplistic assumption that two fundamentally different classes of stimuli - ‘gener... ...
Tập 16 Số 1 - Trang 9-16 - 2010
Computation of motion direction in the vertebrate retinaAbstract
How direction of image motion is detected as early as at the level of the vertebrate eye has been intensively studied in retina research. Although the first direction-selective (DS) retinal ganglion cells were already described in the 1960s and have since then been in the focus of many studies, scientists are still puzzled by the intrica... ...
Tập 18 Số 3 - Trang 49-58 - 2012
The melody of the immature brainAbstract
The periodicity of brain activity became obvious even after the first attempt to capture it, with Hans Berger noting in 1929 that the “electroencephalogram represents a continuous curve with continuous oscillations”. This rhythmicity of neural activity, the ‘melody’ of the brain, has since gained interest as an energy-efficient strategy ... ...
- 2013