Global patterns of breast cancer incidence and mortality: A population‐based cancer registry data analysis from 2000 to 2020 Tập 41 Số 11 - Trang 1183-1194 - 2021
Shaoyuan Lei, Rongshou Zheng, Siwei Zhang, Shaoming Wang, Ru Chen, Kexin Sun, Hongmei Zeng, Jiachen Zhou, Wenqiang Wei
AbstractBackgroundBreast cancer is the most commonly diagnosed cancer and
leading cause of cancer death among women worldwide but has patterns and trends
which vary in different countries. This study aimed to evaluate the global
patterns of breast cancer incidence and mortality and analyze its temporal
trends for breast cancer prevention and control.MethodsBreast cancer incidence
and mortality dat... hiện toàn bộ
Cancer burden of major cancers in China: A need for sustainable actions Tập 40 Số 5 - Trang 205-210 - 2020
Maomao Cao, Li He, Dianqin Sun, Wanqing Chen
AbstractCancer is still a major health problem in China although numerous
efforts have been made for its prevention and control. Findings from this study
showed that lung cancer remains the most common type of cancer diagnosed, and
was attributed to nearly 30% of all cancer‐related deaths. The incidence of the
five most common cancers, in China, in 2015, including cancers of the lungs,
stomach, co... hiện toàn bộ
Mucinous colorectal adenocarcinoma: clinical pathology and treatment options Tập 39 Số 1 - Trang 1-13 - 2019
Cong Luo, Shuyi Cen, Guojun Ding, Wei Wang
AbstractMucinous colorectal adenocarcinoma is a distinct subtype of colorectal
cancer (CRC) characterized by the presence of abundant extracellular mucin which
accounts for at least 50% of the tumor volume. Mucinous colorectal
adenocarcinoma is found in 10%–20% of CRC patients and occurs more commonly in
female and younger patients. Moreover, mucinous colorectal adenocarcinoma is
more frequently l... hiện toàn bộ
Impaired dendritic cell functions in lung cancer: a review of recent advances and future perspectives - 2019
Jingbo Wang, Xue F. Huang, Furong Li
AbstractLung cancer is the leading cause of cancer mortality worldwide.
Dendritic cells (DCs) are the key factors providing protective immunity against
lung tumors and clinical trials have proven that DC function is reduced in lung
cancer patients. It is evident that the immunoregulatory network may play a key
role in the failure of the immune response to terminate tumors. Lung tumors
likely emplo... hiện toàn bộ
Độc tính tim mạch của 5‐fluorouracil và capecitabine ở bệnh nhân Trung Quốc: một nghiên cứu triển vọng Dịch bởi AI Tập 38 Số 1 - Trang 1-7 - 2018
Jianjun Peng, Chao Dong, Chang Wang, Weihua Li, Hui Yu, Min Zhang, Qun Zhao, Bo Zhu, Jun Zhang, Wenliang Li, Fenghua Wang, Qiong Wu, Wenhao Zhou, Ying Yuan, Meng Qiu, Gong Chen
Tóm tắtGiới thiệuĐộc tính tim mạch liên quan đến 5‐fluorouracil (5‐FU) và
capecitabine, từ các bất thường điện tâm đồ không có triệu chứng cho đến nhồi
máu cơ tim nghiêm trọng, đã được báo cáo trong một số nghiên cứu. Tuy nhiên,
tình trạng độc tính tim mạch này ở bệnh nhân Trung Quốc có bệnh ác tính vẫn chưa
được điều tra đến nay. Trong nghiên cứu hiện tại, chúng tôi nhằm đánh giá một
cách triển v... hiện toàn bộ
Laparoscopic versus open pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: a propensity score matching analysis - 2019
Wentao Zhou, Weiwei Jin, Dansong Wang, Chao Lü, Xuefeng Xu, Ren-Chao Zhang, Tiantao Kuang, Yucheng Zhou, Wen-Chuan Wu, Dayong Jin, Yiping Mou, Wenhui Lou
AbstractBackgroundA growing body of evidence supports the use of laparoscopic
pancreaticoduodenectomy (LPD) as an efficient and feasible surgical technique.
However, few studies have investigated its applicability in pancreatic ductal
adenocarcinoma (PDAC), and the long‐term efficacy of LPD on PDAC remains
unclear. This study aimed to compare the short‐ and long‐term outcomes between
LPD and open ... hiện toàn bộ
Modulating the function of ABCB1: in vitro and in vivo characterization of sitravatinib, a tyrosine kinase inhibitor Tập 40 Số 7 - Trang 285-300 - 2020
Yuqi Yang, Ning Ji, Chao‐Yun Cai, Jing‐Quan Wang, Zi‐Ning Lei, Qiu‐Xu Teng, Zhuo‐Xun Wu, Qingbin Cui, Yihang Pan, Zhe‐Sheng Chen
AbstractBackgroundOverexpression of ATP‐binding cassette (ABC) transporter is a
major contributor to multidrug resistance (MDR), in which cancer cells acquire
resistance to a wide spectrum of chemotherapeutic drugs. In this work, we
evaluated the sensitizing effect of sitravatinib, a broad‐spectrum tyrosine
kinase inhibitor (TKI), on ATP‐binding cassette subfamily B member 1 (ABCB1)‐
and ATP‐bindi... hiện toàn bộ
Associations of PGK1 promoter hypomethylation and PGK1‐mediated PDHK1 phosphorylation with cancer stage and prognosis: a TCGA pan‐cancer analysis - 2019
Fei Shao, Xueying Yang, Wei Wang, Juhong Wang, Wei Guo, Xiaoli Feng, Susheng Shi, Qi Xue, Shugeng Gao, Yibo Gao, Zhimin Lu, Jie He
AbstractBackgroundCancer cells reprogram metabolism for proliferation.
Phosphoglycerate kinase 1 (PGK1), as a glycolytic enzyme and newly identified
protein kinase, coordinates glycolysis and mitochondrial metabolism. However,
the clinical significance of PGK1 expression and function in cancer progression
is unclear. Here, we investigated the relationship between the progression and
prognosis of m... hiện toàn bộ