Cancer burden of major cancers in China: A need for sustainable actions Tập 40 Số 5 - Trang 205-210 - 2020
Maomao Cao, Li He, Dianqin Sun, Wanqing Chen
AbstractCancer is still a major health problem in China although numerous efforts have been made for its prevention and control. Findings from this study showed that lung cancer remains the most common type of cancer diagnosed, and was attributed to nearly 30% of all cancer‐related deaths. The incidence of the five most common cancers, in China, in 2015, including ...... hiện toàn bộ Mucinous colorectal adenocarcinoma: clinical pathology and treatment options Tập 39 Số 1 - Trang 1-13 - 2019
Cong Luo, Shuyi Cen, Guojun Ding, Wei Wang
AbstractMucinous colorectal adenocarcinoma is a distinct subtype of colorectal cancer (CRC) characterized by the presence of abundant extracellular mucin which accounts for at least 50% of the tumor volume. Mucinous colorectal adenocarcinoma is found in 10%–20% of CRC patients and occurs more commonly in female and younger patients. Moreover, mucinous colorectal ad...... hiện toàn bộ Độc tính tim mạch của 5‐fluorouracil và capecitabine ở bệnh nhân Trung Quốc: một nghiên cứu triển vọng Dịch bởi AI Tập 38 Số 1 - Trang 1-7 - 2018
Jianjun Peng, Chao Dong, Chang Wang, Weihua Li, Hui Yu, Min Zhang, Qun Zhao, Bo Zhu, Jun Zhang, Wenliang Li, Fenghua Wang, Qiong Wu, Wenhao Zhou, Ying Yuan, Meng Qiu, Gong Chen
Tóm tắtGiới thiệuĐộc tính tim mạch liên quan đến 5‐fluorouracil (5‐FU) và capecitabine, từ các bất thường điện tâm đồ không có triệu chứng cho đến nhồi máu cơ tim nghiêm trọng, đã được báo cáo trong một số nghiên cứu. Tuy nhiên, tình trạng độc tính tim mạch này ở bệnh nhân Trung Quốc có bệnh ác tính vẫn chưa được điều tra đến nay....... hiện toàn bộ Laparoscopic versus open pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: a propensity score matching analysis - 2019
Wentao Zhou, Weiwei Jin, Dansong Wang, Chao Lü, Xuefeng Xu, Ren-Chao Zhang, Tiantao Kuang, Yucheng Zhou, Wen-Chuan Wu, Dayong Jin, Yiping Mou, Wenhui Lou
AbstractBackgroundA growing body of evidence supports the use of laparoscopic pancreaticoduodenectomy (LPD) as an efficient and feasible surgical technique. However, few studies have investigated its applicability in pancreatic ductal adenocarcinoma (PDAC), and the long‐term efficacy of LPD on PDAC remains unclear. This study aime...... hiện toàn bộ Associations of PGK1 promoter hypomethylation and PGK1‐mediated PDHK1 phosphorylation with cancer stage and prognosis: a TCGA pan‐cancer analysis - 2019
Fei Shao, Xueying Yang, Wei Wang, Juhong Wang, Wei Guo, Xiaoli Feng, Susheng Shi, Qi Xue, Shugeng Gao, Yibo Gao, Zhimin Lu, Jie He
AbstractBackgroundCancer cells reprogram metabolism for proliferation. Phosphoglycerate kinase 1 (PGK1), as a glycolytic enzyme and newly identified protein kinase, coordinates glycolysis and mitochondrial metabolism. However, the clinical significance of PGK1 expression and function in cancer progression is unclear. Here, we inve...... hiện toàn bộ Modulating the function of ABCB1: in vitro and in vivo characterization of sitravatinib, a tyrosine kinase inhibitor Tập 40 Số 7 - Trang 285-300 - 2020
Yuqi Yang, Ning Ji, Chao‐Yun Cai, Jing‐Quan Wang, Zi‐Ning Lei, Qiu‐Xu Teng, Zhuo‐Xun Wu, Qingbin Cui, Yihang Pan, Zhe‐Sheng Chen
AbstractBackgroundOverexpression of ATP‐binding cassette (ABC) transporter is a major contributor to multidrug resistance (MDR), in which cancer cells acquire resistance to a wide spectrum of chemotherapeutic drugs. In this work, we evaluated the sensitizing effect of sitravatinib, a broad‐spectrum tyrosine kinase inhibitor (TKI),...... hiện toàn bộ