Abstract Hand, foot and mouth disease (HFMD), a common contagious disease that
usually affects children, is normally mild but can have life-threatening
manifestations. It can be caused by enteroviruses, particularly Coxsackieviruses
and human enterovirus 71 (HEV71) with highly variable clinical manifestations.
In the spring of 2008, a large, unprecedented HFMD outbreak in Fuyang city of
Anhui prov... hiện toàn bộ
Keivan Zandi, Boon‐Teong Teoh, Sing‐Sin Sam, Pooi-Fong Wong, Mohd Rais Mustafa, Sazaly AbuBakar
Abstract Background Dengue is a major mosquito-borne disease currently with no
effective antiviral or vaccine available. Effort to find antivirals for it has
focused on bioflavonoids, a plant-derived polyphenolic compounds with many
potential health benefits. In the present study, antiviral activity of four
types of bioflavonoid against dengue virus type -2 (DENV-2) in Vero cell was
evaluated. Ant... hiện toàn bộ
Brian L. Ellis, Matthew Hirsch, Jenny C. Barker, Jon P. Connelly, Robert J. Steininger, Matthew H. Porteus
Abstract Background The ability to deliver a gene of interest into a specific
cell type is an essential aspect of biomedical research. Viruses can be a useful
tool for this delivery, particularly in difficult to transfect cell types.
Adeno-associated virus (AAV) is a useful gene transfer vector because of its
ability to mediate efficient gene transduction in numerous dividing and
quiescent cell ty... hiện toàn bộ
Kshama Kumari, Shelly Gulati, David F. Smith, Upma Gulati, Richard D. Cummings, Gillian M. Air
AbstractBackgroundHuman influenza viruses are known to bind to sialic acid
linked α2-6 to galactose, but the binding specificity beyond that linkage has
not been systematically examined. H3N2 human influenza isolates lost binding to
chicken red cells in the 1990s but viruses isolated since 2003 have re-acquired
the ability to agglutinate chicken erythrocytes. We have investigated
specificity of bi... hiện toàn bộ