Virology Journal
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Chinese highly pathogenic porcine reproductive and respiratory syndrome virus exhibits more extensive tissue tropism for pigs
Virology Journal - Tập 9 - Trang 1-6 - 2012
The highly pathogenic porcine reproductive and respiratory syndrome virus (PRRSV) emerging in China exhibits high fatality to pigs. However, the mechanism related to the increased pathogenicity of the virus remains unclear. In the present study, the differences in tissue tropism between the highly pathogenic PRRSV strain (JXwn06) and the low pathogenic PRRSV strain (HB-1/3.9) were investigated usi......
Zika virus-induced hyper excitation precedes death of mouse primary neuron
Virology Journal - Tập 15 - Trang 1-13 - 2018
Zika virus infection in new born is linked to congenital syndromes, especially microcephaly. Studies have shown that these neuropathies are the result of significant death of neuronal progenitor cells in the central nervous system of the embryo, targeted by the virus. Although cell death via apoptosis is well acknowledged, little is known about possible pathogenic cellular mechanisms triggering ce......
Evolutionary genomics of APSE: a tailed phage that lysogenically converts the bacterium Hamiltonella defensa into a heritable protective symbiont of aphids
Virology Journal - - 2021
Most phages infect free-living bacteria but a few have been identified that infect heritable symbionts of insects or other eukaryotes. Heritable symbionts are usually specialized and isolated from other bacteria with little known about the origins of associated phages. Hamiltonella defensa is a heritable bacterial symbiont of aphids that is usually infected by a tailed, double-stranded DNA phage n......
Acalculous cholecystitis is a common extrahepatic manifestation of hepatitis E and suggests a more serious condition
Virology Journal - Tập 20 - Trang 1-9 - 2023
This study aimed to understand the incidence and clinical significance of acalculous cholecystitis in patients with acute hepatitis E (HE). A single center enrolled 114 patients with acute HE. All patients underwent imaging of the gallbladder, and patients with gallstones and cholecystectomy were excluded. Acalculous cholecystitis was found in 66 patients (57.89%) with acute HE. The incidence in m......
Rescue and evaluation of a recombinant PRRSV expressing porcine Interleukin-4
Virology Journal - - 2015
Survey of causative agents for acute respiratory infections among patients in Khartoum- State, Sudan, 2010–2011
Virology Journal - Tập 10 - Trang 1-10 - 2013
This study was carried out to determine causative agents of acute respiratory illness of patients in Khartoum State, Sudan. Four hundred patients experiencing respiratory infections within January-March 2010 and January-March 2011 were admitted at Khartoum Hospital and had their throat swab samples subjected to multiplex real-time RT-PCR to detect influenza viruses (including subtypes) and other v......
Heterogeneous virulence of pandemic 2009 influenza H1N1 virus in mice
Virology Journal - Tập 9 - Trang 1-12 - 2012
Understanding the pathogenesis of influenza infection is a key factor leading to the prevention and control of future outbreaks. Pandemic 2009 Influenza H1N1 infection, although frequently mild, led to a severe and fatal form of disease in certain cases that make its virulence nature debatable. Much effort has been made toward explaining the determinants of disease severity; however, no absolute r......
Genome-wide identification of endogenous viral sequences in alfalfa (Medicago sativa L.)
Virology Journal - Tập 18 - Trang 1-5 - 2021
Endogenous viral elements (EVEs) have been for the most part described in animals and to a less extent in plants. The endogenization was proposed to contribute toward evolution of living organisms via horizontal gene transfer of novel genetic material and resultant genetic diversity. During the last two decades, several full-length and fragmented EVEs of pararetroviral and non-retroviral nature ha......
Characterization and specificity of the linear epitope of the enterovirus 71 VP2 protein
Virology Journal - Tập 9 - Trang 1-11 - 2012
Enterovirus 71 (EV71) has emerged as a major causative agent of hand, foot and mouth disease in the Asia-Pacific region over the last decade. Hand, foot and mouth disease can be caused by different etiological agents from the enterovirus family, mainly EV71 and coxsackieviruses, which are genetically closely related. Nevertheless, infection with EV71 may occasionally lead to high fever, neurologic......
Seroprevalence of hepatitis B surface antigen and anti HCV antibody and its associated risk factors among pregnant women attending maternity ward of Felege Hiwot Referral Hospital, northwest Ethiopia: a cross-sectional study
Virology Journal - Tập 12 - Trang 1-9 - 2015
Viral hepatitis is a life-threatening liver disease that has become important public health issue in developing countries including Ethiopia. This study was undertaken to determine the seroprevalence of HBsAgs and anti-HCV antibodies and what socio-demographic factors are associated with sero-positivity of Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) infections among pregnant women attendin......
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