Translational Medicine Communications

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Precision medicine in relapsed or refractory pediatric solid tumors: a collaborative Spanish initiative
Translational Medicine Communications - Tập 4 - Trang 1-11 - 2019
Pablo Gargallo, Jaime Font de Mora, Pablo Berlanga, Inés Calabria, Margarita Llavador, Laia Pedrola, Joaquín Panadero, Sandra Dolz, Ángel Zúñiga, Juan Silvestre Oltra, Paloma Escobar, Yania Yáñez, María José Aparisi, Marina Martinez-Matilla, Vanessa Segura, Carlos Esquembre, María Del Cañizo, María José Moreno, Catalina Márquez, Adela Cañete, Victoria Castel
Understanding pediatric cancer biology is a huge challenge in continuous development that is currently being implemented into the clinical practice thanks to the new high throughput technologies integrated by personalized medicine. We present the results of the Precision Medicine program for children and adolescents with solid tumors in relapse/progression carried out in University La Fe Hospital ... hiện toàn bộ
Forming effective relationships between academia and the medical devices industry with a focus on launching a smart heart valve prosthesis for pediatric patients
Translational Medicine Communications - Tập 4 Số 1 - 2019
Albert Ryszard Liberski, Jonathan T. Butcher, Zbigniew Nawrat, Tal Golesworthy, Dena A. Al Thani
AbstractBackgroundThis article presents examples of how to utilize the research output, to initiate academia-industry interaction, with the ultimate task of launching a new product: a smart heart valve prosthesis for pediatric patients. The article summarizes our efforts in a way that may also be informative to researchers working in fields other than medical devices development. Our task is not t... hiện toàn bộ
PhiΦBreast & theory of spiral cancer new diagnostic techniques for breast cancer detection
Translational Medicine Communications -
Ersilio Trapanese, Giulio Tarro
Abstract Background Today, breast cancer is one of the most aggressive cancers in women and new cases continue to increase worldwide. The incidence of this tumor is kept under control especially with surgery. In order to reduce mortality we need to detect this life threatening disease at an earlier stage. For two years, we have conducted a study for the identification and characterization of suspi... hiện toàn bộ
Correction: Arsenic treatment of acute promyelocytic leukemia affects neutrophil function in a compensatory manner
Translational Medicine Communications - - 2024
Anna Thunstrom Salzer, Constantin F. Urban
Hospitalized COVID-19 patients treated with convalescent plasma in a mid-size city in the Midwest
Translational Medicine Communications - Tập 5 - Trang 1-6 - 2020
William R. Hartman, Aaron S. Hess, Joseph P. Connor
SARS-CoV-2 and its associated disease, COVID-19, has infected over seven million people world-wide, including two million people in the United States. While many people recover from the virus uneventfully, a subset of patients will require hospital admission, some with intensive care needs including intubation, and mechanical ventilation. To date there is no cure and no vaccine is available. Passi... hiện toàn bộ
CD8+ tumor infiltrating lymphocytes strongly correlate with molecular subtype and clinico-pathological characteristics in breast cancer patients from Sudan
Translational Medicine Communications - Tập 1 - Trang 1-6 - 2016
Mahmoud Mohamed, Hina Sarwath, Nada Salih, Devendra Bansal, Prem Chandra, Nazik E. Husain, Lotfi Chouchane, Ali A. Sultan, Shahinaz Bedri
Breast Cancer in the Middle East and North Africa region (MENA) occurs in a younger age group of patients and is more aggressive than in Europe and North America. Little is known about the presence of immune infiltration and clinico-pathologic correlates in patients from the MENA region. Immune infiltration of most solid tumors carries a prognostic role. Adaptive immune cells and cytotoxic T-cells... hiện toàn bộ
Statins in patients with COVID-19: a retrospective cohort study in Iranian COVID-19 patients
Translational Medicine Communications - Tập 6 - Trang 1-14 - 2021
Payam Peymani, Tania Dehesh, Farnaz Aligolighasemabadi, Mohammadamin Sadeghdoust, Katarzyna Kotfis, Mazaher Ahmadi, Parvaneh Mehrbod, Pooya Iranpour, Sanaz Dastghaib, Ahmad Nasimian, Amir Ravandi, Biniam Kidane, Naseer Ahmed, Pawan Sharma, Shahla Shojaei, Kamran Bagheri Lankarani, Andrzej Madej, Nima Rezaei, Tayyebeh Madrakian, Marek J. Los, Hagar Ibrahim Labouta, Pooneh Mokarram, Saeid Ghavami
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has profoundly affected the lives of millions of people. To date, there is no approved vaccine or specific drug to prevent or treat COVID-19, while the infection is globally spreading at an alarming rate. Because the development of effective vaccines or novel drugs coul... hiện toàn bộ
Comparative molecular cell-of-origin classification of diffuse large B-cell lymphoma based on liquid and tissue biopsies
Translational Medicine Communications - - 2020
Ewan Hunter, Ronald McCord, Aroul Ramadass, Jayne Green, Jurjen W. Westra, Kirsten Mundt, Alexandre Akoulitchev
Abstract Background Diffuse large B-cell lymphoma (DLBCL) is a heterogenous blood cancer, but can be broadly classified into two main subtypes, germinal center B-cell-like (GCB) and activated B-cell-like (ABC). GCB and ABC subtypes have very different clinical courses, with ABC having a much worse survival prognosis. It has been observed that patients with different subtypes also respond different... hiện toàn bộ
Oncolytic virus-based suicide gene therapy for cancer treatment: a perspective of the clinical trials conducted at Henry Ford Health
Translational Medicine Communications - Tập 8 - Trang 1-21 - 2023
Shivani Thoidingjam, Sushmitha Sriramulu, Svend Freytag, Stephen L. Brown, Jae Ho Kim, Indrin J. Chetty, Farzan Siddiqui, Benjamin Movsas, Shyam Nyati
Gene therapy manipulates or modifies a gene that provides a new cellular function to treat or correct a pathological condition, such as cancer. The approach of using gene manipulation to modify patient’s cells to improve cancer therapy and potentially find a cure is gaining popularity. Currently, there are 12 gene therapy products approved by US-FDA, EMA and CFDA for cancer management, these inclu... hiện toàn bộ
Lost in translation: barriers and progress in harnessing basic medical science into community practice in Indonesia
Translational Medicine Communications - Tập 5 - Trang 1-5 - 2020
Ajib Diptyanusa, Mubasysyir Hasanbasri
Translational research carries over fundamental laboratory research findings into clinical and community settings in order to ‘translate’ the findings into practice. In addition to its potential in accelerating the time of basic discoveries to be delivered into the population, translational studies also provide opportunities for interdisciplinary collaborations in identifying knowledge gaps. Howev... hiện toàn bộ
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