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Omalizumab in Severe Refractory Vernal Keratoconjunctivitis in Children: Case Series and Review of the Literature
Springer Science and Business Media LLC - Tập 6 - Trang 195-206 - 2016
Vernal keratoconjunctivis (VKC) is a severe form of pediatric ocular allergy, characterized by acute and chronic corneoconjunctival inflammation that may lead to visual sequelae. Although topical immunosuppressive drugs such as cyclosporine are usually effective, some severe forms may be refractory and require prolonged steroid therapy. Very few papers report the use of omalizumab in VKC in the li...... hiện toàn bộ
Effect of Photochromic Contact Lens Wear on Indoor Visual Performance and Patient Satisfaction
Springer Science and Business Media LLC - Tập 11 - Trang 1847-1855 - 2022
To quantitatively assess visual performance and patient satisfaction during photochromic contact lens (CL) wear in an indoor environment. This observational study comprised 82 eyes of 41 healthy subjects (mean age ± standard deviation, 21.7 ± 0.7 years) who had no ophthalmic diseases except for refractive errors at Kitasato University in 2021. We prospectively compared visual acuity, kinetic visua...... hiện toàn bộ
2-Year Real-World Outcomes with Intravitreal Aflibercept in Neovascular Age-Related Macular Degeneration: Literature Review and Meta-analysis of Patient-Relevant Outcomes
Springer Science and Business Media LLC - Tập 10 - Trang 397-411 - 2021
The 96 weeks’ assessment from the VIEW studies provided insights into the long-term efficacy of intravitreal aflibercept (IVT-AFL) in neovascular age-related macular degeneration (nAMD) and demonstrated that it was possible to maintain long-term outcomes while moving from a fixed bimonthly regimen in Year 1 to a variable dosing regimen in Year 2. The aim of this analysis was to perform a literatur...... hiện toàn bộ
Identification of Treatment Protocols for Effective Cross-Linking of the Peripheral Cornea: An Experimental Study
Springer Science and Business Media LLC - Tập 11 - Trang 2057-2066 - 2022
This study aimed to test and evaluate modified corneal cross-linking (CXL) protocols regarding improved treatment effects on the peripheral cornea in terms of tissue stability and cellular response. Peripheral CXL (pCXL) was performed within a ring of 9–11 mm of 36 human donor corneas with variations in applied energy (5.4, 7.2, and 10 J/cm2) at 9 mW/cm2 irradiance. Each energy level was additiona...... hiện toàn bộ
Medical Therapy and Scleral Windows for Uveal Effusion Syndrome: A Case Series and Literature Review
Springer Science and Business Media LLC - Tập 12 - Trang 35-53 - 2022
Uveal effusion syndrome (UES) is a rare ocular disease causing idiopathic uveal effusion, often with associated ciliochoroidal and retinal detachment. UES diagnosis is challenging because of overlapping features with other ocular inflammatory, neoplastic, iatrogenic, and drug-induced causes of uveal effusion. While several successful surgical treatments have been described, such as full-thickness ...... hiện toàn bộ
Missed Hospital Appointments of Patients Receiving Ranibizumab Therapy for Neovascular Age-Related Macular Degeneration
Springer Science and Business Media LLC - Tập 4 - Trang 43-49 - 2015
The aim of this study was to investigate the frequency and duration of missed hospital appointments (MHAs) in a consecutive cohort of patients treated with ranibizumab for neovascular age-related macular degeneration (nAMD) and to assess their impact on outcomes of therapy in a real-world clinical setting. Retrospective, cross-sectional study of consecutive patients attending medical retina clinic...... hiện toàn bộ
Evaluation of Retinal Vascularity Index in Patients with COVID-19: A Case–Control Study
Springer Science and Business Media LLC - Tập 12 - Trang 879-894 - 2022
The purpose of this study was to evaluate the impact of COVID-19 infection on retinal microvasculature by topographically mapping the retinal arteriole-to-venule ratio (AVR).
In a comparative cross-sectional case–control study, fundus photos were obtained in COVID-19-infected patients and healthy controls. AVT was measured over 16 points across the retina using retinal vascularity index (RVI)—a n...... hiện toàn bộ
OCT Angiography of the Choriocapillaris in Central Serous Chorioretinopathy: A Quantitative Subgroup Analysis
Springer Science and Business Media LLC - Tập 8 - Trang 75-86 - 2019
To quantify optical coherence tomography angiography (OCTA) signal changes at the level of the choriocapillaris (CC) in patients with different stages of central serous chorioretinopathy (CSC) and to explore any correlation between subretinal fluid (SRF) and retinal pigment epithelium (RPE) alterations and the OCTA CC signal. One hundred one CSC eyes and 42 healthy control eyes were included in th...... hiện toàn bộ
Real-World Persistence and Treatment Interval in Patients with Diabetic Macular Edema Treated with Anti-Vascular Endothelial Growth Factors in the USA
Springer Science and Business Media LLC - Tập 12 Số 5 - Trang 2465-2477 - 2023
Foveal Eversion: A Possible Biomarker of Persistent Diabetic Macular Edema
Springer Science and Business Media LLC - Tập 10 - Trang 115-126 - 2021
We aimed to evaluate the impact of foveal eversion on treatment response and persistent diabetic macular edema (DME). The study was designed as interventional and prospective. DME eyes were treated with ranibizumab and/or dexamethasone (DEX) implants, or with fluocinolone acetonide (FAc) implants. FAc-treated eyes were eventually retreated by additional ranibizumab injections. Main outcome measure...... hiện toàn bộ
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