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Ultrasound neuromodulation of cultured hippocampal neurons
Springer Science and Business Media LLC - Tập 14 - Trang 79-89 - 2023
Ultrasound is becoming an emerging and promising method for neuromodulation due
to its advantage of noninvasiveness and its high spatial resolution. However,
the underlying principles of ultrasound neuromodulation have not yet been
elucidated. We have herein developed a new in vitro setup to study the
ultrasonic neuromodulation, and examined various parameters of ultrasound to
verify the effective...
Prediction of complications in diabetes mellitus using machine learning models with transplanted topic model features
Springer Science and Business Media LLC - - 2024
AbstractPurpose: This study aims to predict the progression of Diabetes Mellitus
(DM) from the clinical notes through machine learning based on latent Dirichlet
allocation (LDA) topic modeling. Particularly, 174,427 clinical notes of DM
patients were collected from the electronic medical record (EMR) system of the
Seoul National University Hospital outpatient clinic. Method: We developed a
model t...
Assessment of shape memory alloy stent deployment in a stenosed artery
Springer Science and Business Media LLC - Tập 1 - Trang 226-231 - 2011
Shape memory alloy (SMA) stents have been used increasingly for the treatment of
complex arterial occlusions. There is an immediate need to quantify the
mechanical performance of SMA stents to open occluded arteries. The stent
crimping and expanding process was assessed through both numerical modeling and
in-vitro studies. The implantation of a SMA stent in curved arteries with
eccentric stenosis ...
Analysis of induced dynamic biceps EMG signal complexity using Markov transition networks
Springer Science and Business Media LLC - - 2024
Surface electromyography (sEMG) is a non-invasive technique to characterize
muscle electrical activity. The analysis of sEMG signals under muscle fatigue
play a crucial part in the branch of neurorehabilitation, sports medicine,
biomechanics, and monitoring neuromuscular pathologies. In this work, a method
to transform sEMG signals to complex networks under muscle fatigue conditions
using Markov t...
Recent functional near infrared spectroscopy based brain computer interface systems: Developments, applications and challenges
Springer Science and Business Media LLC - Tập 4 - Trang 223-230 - 2014
Functional Near Infrared Spectroscopy (fNIRS) based Brain Computer Interface
(BCI) systems have grown in popularity in the last years, and has shown itself
as a useful tool in developing portable and convenient BCI systems. The purpose
of this review paper is to highlight the recent developments, applications, and
challenges that research groups have achieved in the field of fNIRS-BCI. We will
sho...
Margetuximab conjugated-PEG-PAMAM G4 nano-complex: a smart nano-device for suppression of breast cancer
Springer Science and Business Media LLC - Tập 12 - Trang 317-329 - 2022
Breast cancer due to its high incidence and mortality is the second leading
cause of death among females. On the other hand, nanoparticle-based drug
delivery is one of the most promising approaches in cancer therapy, nowadays.
Hence, margetuximab- and polyethylene glycol-conjugated PAMAM G4 dendrimers were
efficiently synthesized for targeted delivery of quercetin (therapeutic agent)
to MDA-MB-231...
Strategies for minimizing glial response to chronically-implanted microelectrode arrays for neural interface
Springer Science and Business Media LLC - Tập 4 - Trang 120-128 - 2014
For several decades, the intracortical penetrating microelectrode arrays have
been widely employed for the purpose of neural recording and stimulation in
nervous system. However, the long-term application is limited due to the tissue
reaction to the implanted electrode array. The tissue response includes the
degeneration of nerve cells as well as the formation of dense glial sheath
adjacent the im...
Wearable sensing for liquid intake monitoring via apnea detection in breathing signals
Springer Science and Business Media LLC - - 2014
Developing a control framework for self-adjusting prosthetic sockets incorporating tissue injury risk estimation and generalized predictive control
Springer Science and Business Media LLC - Tập 12 - Trang 59-73 - 2021
To perform activities of daily living (ADL), people with lower limb amputation
depend on the prosthetic socket for stability and proprioceptive feedback.
Poorly fitting sockets can cause discomfort, pain, limb tissue injuries, limited
device usage, and potential rejection. Semi-passively controlled adjustable
socket technologies exist, but these depend upon the user’s perception to
determine safe ...
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