Michael T. Heneka, Douglas T. Golenbock, Eicke Latz, Dave Morgan, Robert H. Brown
AbstractIncreasing evidence suggests that infection with Sars-CoV-2 causes neurological deficits in a substantial proportion of affected patients. While these symptoms arise acutely during the course of infection, less is known about the possible long-term consequences for the brain. Severely affected COVID-19 cases experience high levels of proinflammatory cytokin...... hiện toàn bộ
Jeffrey L. Cummings, Paul M. Thompson, Bruno Dubois, Lutz Frölich, Clifford R. Jack, Roy Jones, John C. Morris, Joel Raskin, Sherie A. Dowsett, Philip Scheltens
AbstractThe global impact of Alzheimer’s disease (AD) continues to increase, and focused efforts are needed to address this immense public health challenge. National leaders have set a goal to prevent or effectively treat AD by 2025. In this paper, we discuss the path to 2025, and what is feasible in this time frame given the realities and challenges of AD drug dev...... hiện toàn bộ
Piotr Lewczuk, Natalia Ermann, Ulf Andréasson, Christian Schultheis, Jana Podhorná, Philipp Spitzer, Juan Manuel Maler, Johannes Kornhuber, Kaj Blennow, Henrik Zetterberg